Ecofol Tablet

Overview Ecofol Tablet

Ecofol, containing calcium folinate pentahydrate, acts as a crucial adjunct in methotrexate-based chemotherapy regimens. Calcium folinate pentahydrate is the salt form of folinic acid, a 5-formyl tetrahydrofolic acid derivative. Biologically active as a reduced folic acid, it functions similarly to folic acid, facilitating purine and pyrimidine synthesis despite dihydrofolate reductase inhibition. This allows for continued, albeit limited, DNA replication and RNA transcription. Its role in chemotherapy is twofold: enhancing therapeutic efficacy and mitigating toxicity. Ecofol also finds application in treating megaloblastic anemia. Always use under professional medical guidance.