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Gonorrhea

Gonorrhea

Overview of Gonorrhea

Gonorrhea is a sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoeae. This infection is passed between individuals through sexual contact, including oral, vaginal, and anal intercourse. Pregnant women can also pass the infection to their babies during childbirth. Both men and women can be affected by gonorrhea.


The infection primarily targets the reproductive organs in both genders, as well as the urethra, eyes, and throat. Although anyone can contract gonorrhea, it is most prevalent among individuals aged 15 to 24. The disease often does not exhibit symptoms, and even when symptoms are present, they are typically mild and nonspecific. In women, the symptoms can sometimes be mistaken for a bladder or vaginal infection. Diagnostic tests involve swabs from genital areas, with the presence of bacteria confirmed through nucleic acid amplification tests or culture methods.


Gonorrhea is treatable with antibiotics. If left untreated, it can result in long-term health issues like pelvic inflammatory disease (in women) and epididymitis (in men). Safe sexual practices, such as using condoms and dental dams and limiting sexual partners, can help prevent the spread of gonorrhea.

Important Facts of Gonorrhea

Usually seen in

Usually seen in

  • All age groups, with higher incidence in those aged 15-24.
Gender affected

Gender affected

  • Affects both men and women, with women more commonly affected.
Body part(s) involved

Body part(s) involved

  • Urethra,
  • Vagina,
  • Uterus,
  • Penis,
  • Cervix,
  • Throat.
Prevalence

Prevalence

  • 30.6 million cases worldwide (2016).
Mimicking Conditions

Mimicking Conditions

  • Chlamydia,
  • Trichomoniasis,
  • Syphilis,
  • Mycoplasma genitalium,
  • Herpes simplex virus,
  • Conjunctivitis,
  • Urethritis,
  • Cervicitis,
  • Proctitis,
  • Pharyngitis,
  • Arthritis.
Necessary health tests/imaging

Necessary health tests/imaging

  • Physical examination,
  • Nucleic acid amplification test (NAAT),
  • Culture test,
  • Smear test.
Treatment

Treatment

  • Ceftriaxone,
  • Doxycycline,
  • Gentamicin,
  • Azithromycin,
  • Gemifloxacin,
  • Amoxicillin,
  • Erythromycin.
Specialists to consult

Specialists to consult

  • General physician,
  • Infectious disease specialist,
  • Gynecologist.


Symptoms Of Gonorrhea

The time between exposure to the bacteria and the appearance of symptoms varies: typically 10 days in women and 1-3 days in men. Symptoms include:


A. Symptoms in Men (Uncomplicated Gonorrhea)

  • Urethral discharge
  • Painful urination (dysuria)
  • Frequent urination
  • Urinary itchiness
  • Painful erections


B. Symptoms in Women (Uncomplicated Gonorrhea)

  • Painful urination (dysuria)
  • Blood in urine (hematuria)
  • Inflammation around the anus
  • Increased vaginal discharge


C. Complicated Gonorrhea Symptoms in Men


Epididymitis (inflammation of the epididymis): Symptoms include:

  • Swelling and pain in the epididymis, groin, and lower abdomen
  • Discharge from the urethra


Seminal Vesiculitis (inflammation of the seminal vesicles): Symptoms include:

  • Painful urination and frequent urination
  • Blood in urine and semen
  • Abdominal pain


Prostatitis (inflammation of the prostate gland): Symptoms include:

  • Chills and fever
  • Frequent urination and pubic pain


D. Complicated Gonorrhea Symptoms in Women


Pelvic Inflammatory Disease (PID) (infection of the female genital tract): Symptoms include:

  • Chills, fever, and nausea
  • Abdominal pain and irregular vaginal bleeding


Perihepatitis (inflammation of the liver capsule): Symptoms include:

  • Severe upper abdominal pain
  • Nausea, vomiting, and fever


E. Symptoms of Gonorrhea in Other Areas


Oral Gonorrhea (Pharyngeal Gonorrhea): Symptoms include:

  • Sore throat, difficulty swallowing
  • Redness and white spots in the throat
  • Swollen lymph nodes and fever


Gonococcal Conjunctivitis (GC): Infection of the eyes, often contracted during childbirth. Symptoms include:

  • Red eyes and thick pus in the eyes
  • Swollen eyelids and cloudy cornea


Proctitis (inflammation of the rectum lining) caused by anal-genital intercourse: Symptoms include:

  • Itching, burning, or discharge from the anus
  • Rectal bleeding, pain, and frequent urge to pass stool


Triggering Factors Of Gonorrhea

Gonorrhea is caused by the bacterium Neisseria gonorrhoeae, an obligate pathogen that requires a host to survive and propagate. This bacterium is primarily found in the discharge from the penis or vagina. Gonorrhea can be transmitted via:


  • Unprotected vaginal, oral, or anal sex
  • Sharing sex toys or vibrators
  • Transmission from mother to baby during childbirth


The bacterium does not survive outside the human body, so it is not spread by casual contact like kissing, hugging, or sharing swimming pools, toilet seats, towels, or eating utensils.

Types Of Gonorrhea

Gonorrhea can be classified as either uncomplicated or complicated:


  • Uncomplicated Gonorrhea: More common and typically results in urogenital, anogenital, or pharyngeal infections.
  • Complicated Gonorrhea: Involves the spread of the bacteria to joints and other tissues, leading to more severe health complications.


Potential Risks for Gonorrhea

Your likelihood of contracting gonorrhea increases if you:


  • Engage in unprotected oral, anal, or vaginal sex with an infected person
  • Have a weakened immune system
  • Have previously been diagnosed with gonorrhea
  • Have multiple sexual partners
  • Are involved with a partner who has multiple sexual partners
  • Are sexually active
  • Work as a sex worker
  • Have a sexual partner from an area with high prevalence of gonorrhea or have a history of gonorrhea or other STIs, including HIV


A lack of sexual education and low socioeconomic status can also contribute to a higher risk of gonorrhea. Additionally, if a condom breaks during sex with an infected partner, the risk of gonorrhea increases. Men who engage in sexual activity with other men (MSM) have a higher likelihood of contracting gonorrhea.

Diagnosis Of Gonorrhea

To confirm gonorrhea, laboratory tests detect the bacteria from samples taken from the urethra, rectum, throat, or eyes. In some cases, urine samples may also be used. If you experience any symptoms of gonorrhea, refrain from sexual activity until test results are confirmed as negative. The diagnostic tests include:


Physical Examination:

This involves a healthcare provider looking for visible signs of gonorrhea, such as discharge from the throat, skin rashes, eye symptoms, or abdominal pain.


Nucleic Acid Amplification Test (NAAT):

This method detects the genetic material of Neisseria gonorrhoeae from urine or swab samples. Swabs from the urethra are taken in men, while samples are taken from the vagina or cervix in women. Rectal or pharyngeal samples may also be taken.


Culture Test:

Widely used due to its high specificity, this test can identify gonorrhea from samples taken from the throat, urethra, vagina, or rectum (but not urine).


Smear Test:

Used primarily in men to diagnose uncomplicated gonorrhea by examining urethral smears under a microscope.


Preventive Measures Of Gonorrhea

Since gonorrhea is spread through sexual fluids, it can be prevented by practicing safer sex, such as:


  • Using condoms, dental dams, or latex/nitrile gloves during oral, anal, or vaginal sex
  • Getting regular STD tests if you are sexually active
  • Avoiding sexual activity with your partner until they have completed treatment for any STDs
  • Washing your hands after touching your partner’s genitals
  • Regularly cleaning sex toys with soap and water
  • Using condoms with sex toys
  • Limiting the number of sexual partners


Note: Washing the genitals, urinating, or douching after sex does not prevent gonorrhea.


Specialist to Consult

Gonorrhea can affect anyone who is sexually active. Seek medical attention immediately if you experience symptoms like genital discharge, painful urination, rashes, or other unusual skin conditions. It’s also important to consult a healthcare provider if your partner has recently been diagnosed with an STD.

Annual gonorrhea screening is recommended for:

  • Young sexually active individuals
  • Older individuals with risk factors, such as multiple sexual partners


Pregnant women should also undergo STD testing, including for gonorrhea, as part of routine care to reduce potential complications for the baby.

The ideal place to visit is a sexual health clinic, also known as a genitourinary medicine (GUM) clinic. Specialists who can help treat gonorrhea include:

  • General physicians
  • Infectious disease specialists
  • Gynecologists


Treatment Of Gonorrhea

Gonorrhea is treatable with antibiotics. Treatment options vary depending on the symptoms or type of infection:


Urogenital Infections

For managing urogenital gonorrhea, the following antibiotics are typically prescribed:

  • Ceftriaxone
  • Doxycycline


If a person is allergic to ceftriaxone, alternative antibiotics may be used, such as:


  • Azithromycin
  • Gemifloxacin
  • Gentamicin


Gonococcal Conjunctivitis

Newborns who develop gonococcal conjunctivitis are treated with ceftriaxone based on their body weight. Their eyes should be rinsed every hour with normal saline. The mother of an infected newborn should also be tested for gonorrhea and treated if necessary.


Gonorrhea During Pregnancy

For pregnant women, Erythromycin or Amoxicillin is recommended for treating gonorrhea.


Follow-Up Care

Follow-up testing is typically unnecessary for rectal and genital infections, unless symptoms persist after treatment. For throat infections, a re-evaluation is recommended 7-14 days after treatment. Additionally, a re-test is suggested after 3 months to check for possible re-infection.


Sexual Partner Management

Anyone diagnosed with gonorrhea should ensure that their sexual partner(s) are tested, especially if they had sexual activity within two months before the symptoms appeared. Sexual activity should be avoided until both the infected individual and their partner have completed treatment. For neonates diagnosed with gonococcal conjunctivitis, the mother and her sexual partner should also be tested for gonorrhea.

Health Complications Of Gonorrhea

If untreated, gonorrhea can spread throughout the body, leading to serious complications:


Pelvic Inflammatory Disease (PID)

Gonorrhea can spread from the vagina to other parts of the female reproductive system, such as the fallopian tubes and uterus. Symptoms include fever and abdominal pain and can cause long-term complications like:

  • Chronic pelvic pain
  • Infertility
  • Abscesses
  • Endometritis
  • Ectopic pregnancy


Pregnancy Complications

In pregnant women, gonorrhea increases the risk of miscarriage, premature labor, and early abortion. It can also be transmitted to the fetus, potentially causing conditions such as conjunctivitis, joint pain, blindness, and blood infections. Early treatment can reduce the likelihood of these complications.


Male Infertility

Gonorrhea can cause infections in the testicles, prostate gland, and epididymis, potentially leading to infertility in men.


Disseminated Gonococcal Infection (DGI)

If left untreated, gonorrhea can spread into the bloodstream, causing DGI, which may result in:

  • Septic arthritis (joint inflammation)
  • Tenosynovitis (inflammation of tendons)
  • Endocarditis (heart inflammation)
  • Dermatitis (skin inflammation)


Fitz-Hugh-Curtis Syndrome

This condition, also known as perihepatitis, is a result of PID and involves inflammation of the liver capsule, causing persistent pain due to adhesions in the liver.


Alternative Therapies For Gonorrhea

Homemade Remedies for Gonorrhea

While antibiotics are the main treatment for gonorrhea, some home remedies may support recovery:


  1. Garlic: Known for its antibacterial properties, garlic may help in treating bacterial infections like gonorrhea.
  2. Apple Cider Vinegar: It has natural antibacterial qualities. However, it should be consumed using a metal straw to avoid tooth damage.
  3. Aloe Vera Gel: With antibacterial and anti-inflammatory properties, aloe vera helps soothe and heal skin.
  4. Goldenseal: This plant has antimicrobial properties and is available in capsules or creams. Always consult a doctor for the correct dosage.
  5. Echinacea: This plant, used to reduce inflammation, can be applied topically in creams or gels.


Lifestyle Modifications Gonorrhea

Although gonorrhea can be managed with antibiotics, the following precautions should be taken:


  • Avoid Sexual Activity: Do not engage in sexual activity for at least one week after completing treatment. Wait until symptoms have fully resolved.


  • Retesting: If symptoms persist after treatment or you are concerned about possible antibiotic resistance, retesting is advised.


  • Testing for Other STIs: People with gonorrhea are more susceptible to other STIs, including HIV. Therefore, it’s important to get tested for other infections.


Frequently Asked Questions

Yes, it is possible to contract gonorrhea again if exposed to an untreated partner or a new sexual partner.
Consult your healthcare provider immediately. Gonorrhea can be safely treated with antibiotics during pregnancy. Avoid sexual activity until both you and your partner have fully recovered.
Yes, gonorrhea is highly contagious and spreads through sexual fluids. However, it does not transmit through casual contact like kissing or hugging.
Wait at least seven days after completing treatment before resuming sexual activity, even if symptoms are gone. This helps prevent reinfection.

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