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Admine 400 Tablet

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Prescription Required

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Adley Formulations

Salt Composition

Imatinib mesylate (400mg)

Overview Admine 400 Tablet

Admine 400 tablets combat various cancers, primarily blood cancers like chronic myeloid leukemia and acute lymphocytic leukemia, as well as gastrointestinal stromal tumors. Its mechanism involves targeting specific proteins crucial for cancer cell proliferation and metastasis. This medication also treats dermatofibrosarcoma protuberans (a skin tumor) and aggressive systemic mastocytosis (a bone marrow disorder). Administer with food, consistently at the same time daily for optimal efficacy. Treatment duration is individualized, determined by response and need. Incorrect dosage or overuse may lead to severe adverse reactions. Therapeutic benefits might not be apparent for weeks or months; discontinue only under physician guidance. Frequent side effects include swelling, nausea, vomiting, muscle spasms, musculoskeletal pain, diarrhea, skin rashes, tiredness, and stomach pain. Report unexpected, rapid weight gain immediately. Regular blood count and liver function monitoring is often recommended. Avoid driving or tasks demanding concentration if dizziness or blurred vision occur. Inform your healthcare provider of all concurrent medications, as interactions are possible. This medication is contraindicated during pregnancy and breastfeeding; reliable contraception for both partners is crucial throughout treatment.

Uses of Admine 400 Tablet

Oncological Management

Major Benefits of Admine 400 Tablet:

Consume this medication precisely as your physician directs, adhering to both the prescribed dosage and treatment period. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Administer the 400mg tablet with a meal.

Common Side effects of Admine 400 Tablet:

  • Edema (swelling)
  • Nausea
  • Vomiting
  • Muscle cramp
  • Musculoskeletal (bone, muscle or joint) pain
  • Diarrhea
  • Rash
  • Fatigue
  • Abdominal pain
  • Bleeding
  • Breathing problems
  • Cough
  • Weight gain
  • Dry eye
  • Dizziness
  • Hemorrhage

How to use Admine 400 Tablet:

Follow your doctor's instructions precisely regarding dosage and treatment length for this medication. Ingest the tablet whole; avoid chewing, crushing, or breaking it. Consume Admine 400 Tablet with a meal.

How Admine 400 Tablet works:

Admine 400 Tablet combats cancer by targeting the bcr-abl tyrosine kinase enzyme, a protein crucial for the uncontrolled growth of cancerous cells. Its mechanism involves blocking this enzyme's activity, thus curbing the proliferation of bcr-abl positive cells and triggering their programmed self-destruction (apoptosis). This action helps control or retard cancer progression.

SAFETY ADVICE

AlcoholAlcoholCONSULT YOUR DOCTOR

Alcohol consumption alongside Admine 400 Tablet lacks established safety data. Seek medical advice before combining them.

PregnancyPregnancyCONSULT YOUR DOCTOR

Taking Admine 400 Tablet during pregnancy is considered unsafe due to confirmed risks to the fetus. In exceptional, life-threatening circumstances, a physician might prescribe it if the potential benefits outweigh the known hazards. Always seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Use of Admine 400 Tablet during breastfeeding is likely unsafe. Preliminary human data indicates potential transfer to breast milk, posing a risk to the infant. Nursing mothers must discontinue breastfeeding throughout treatment and for a fortnight following cessation of Admine 400 Tablet.

DrivingDrivingUNSAFE

Taking Admine 400 Tablet might impair your driving ability due to potential adverse reactions.

KidneyKidneyCAUTION

For individuals with impaired kidney function, Admine 400 Tablet requires careful administration. Dosage modification may be necessary. Physician consultation is advised.

LiverLiverCAUTION

Patients with significant hepatic impairment should use Admine 400 Tablets cautiously, potentially requiring dosage modification. Physician consultation is advised.

What if you forget to take Admine 400 Tablet :

Omit any missed Admine 400 Tablet dose and resume your regular medication regimen. Avoid taking a double dose.

Facts to Know About Admine 400 Tablet

LabelValue
Type of Compound Aniline-benzoic acid derivative
Addiction potential None.
Medication Category Cancer treatments
Mechanism of Action Kinase inhibitors targeting tyrosine

FAQs on Admine 400 Tablet

Optimal administration involves ingestion with water and a meal to minimize esophageal and gastric irritation. Should swallowing present difficulty, dissolve the tablets in water or apple juice (roughly 50 ml for a 100 mg tablet, 200 ml for a 400 mg tablet). Stir thoroughly to ensure complete dissolution before immediate consumption.
Taking Admine 400 Tablets might lead to feelings of dizziness, lightheadedness, or sleepiness in certain individuals. It's important to understand your personal reaction to the medication before driving or using equipment.
Adhere strictly to your physician's instructions and attend all scheduled appointments when using Admine 400 Tablet. Consistent monitoring is crucial for treatment efficacy. This may involve routine blood work, weight monitoring, and urinalysis to detect potential adverse reactions early. Reliable contraception is necessary during treatment. Report any pregnancy immediately to your doctor. Inform your doctor about Admine 400 Tablet use before beginning any new medication.
This medication can significantly increase your skin's sensitivity to sunlight. Sun exposure could result in a skin rash, itching, redness, or severe sunburn. While outside, wear protective clothing and apply sunscreen with an SPF of 15 or greater. Report any skin burning to your physician immediately.
Several medications interact negatively with Admine 400 Tablet, such as paracetamol. Avoid self-treating while using Admine 400 Tablet. Other interacting drugs include cyclosporin, dexamethasone (a corticosteroid), warfarin, antivirals for AIDS, and some treatments for bacterial infections, elevated cholesterol, hypertension, cardiovascular disease, and mental health conditions including depression. Always consult your physician before starting any new medication, and disclose your Admine 400 Tablet regimen.
Numerous CML patients have experienced positive outcomes with Admine 400 Tablet, exhibiting improved survival rates. However, your physician, considering your condition, blood work, treatment response, and overall health, is best positioned to advise on its suitability for you.
Admine 400 Tablet
689
MRP 800
13% off