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Avazide MF 40mg/500mg Tablet SR

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Prescription Required

Marketer

Alvio Pharma

Salt Composition

Gliclazide (40mg) + Metformin (500mg)

Overview Avazide MF 40mg/500mg Tablet SR

Diabexe Duo 40mg/500mg Extended-Release Tablets are classified as antidiabetic medications. This dual-action formulation treats type 2 diabetes in adults by managing blood glucose levels. Diabexe Duo should be ingested with food, consistently at the same time daily for optimal effectiveness. Dosage is determined and adjusted by your physician based on your glycemic control. Continuous use is vital; discontinuation without medical consultation risks elevated blood sugar, potentially leading to kidney complications, vision impairment, neuropathy, and limb loss. This medication forms part of a comprehensive diabetes management plan encompassing a balanced diet, regular physical activity, and weight management as directed by your doctor. Lifestyle modifications are crucial for diabetes control. Common side effects include hypoglycemia (low blood sugar), characterized by sweating, dizziness, headache, and tremors; constipation; and vomiting. Carrying a rapid-acting glucose source (e.g., sugary snacks, fruit juice) is recommended to counter hypoglycemia, which is exacerbated by alcohol consumption. Other possible side effects include altered taste, nausea, diarrhea, abdominal discomfort, headache, and upper respiratory infections. Weight gain may occur. Diabexe Duo is contraindicated in type 1 diabetes, diabetic ketoacidosis, and severe hepatic or renal impairment. Individuals with a history of heart disease should inform their physician before commencing treatment. Consult your doctor before using this medication if pregnant or breastfeeding. Regular blood glucose monitoring and periodic blood tests to assess blood cell counts and liver function are necessary.

Uses of Avazide MF 40mg/500mg Tablet SR

Adult-onset diabetes

Major Benefits of Avazide MF 40mg/500mg Tablet SR:

Follow your doctor's instructions precisely regarding the dosage and treatment length for this medication. Ingest the Avazide MF 40mg/500mg Tablet SR whole; do not crush, chew, or divide it. Administer this medication with food.

Common Side effects of Avazide MF 40mg/500mg Tablet SR:

  • Hypoglycemia (low blood glucose level)
  • Headache
  • Dizziness
  • Diarrhea
  • Upper respiratory tract infection
  • Nausea
  • Flatulence
  • Constipation

How to use Avazide MF 40mg/500mg Tablet SR:

Consume this medication precisely as prescribed by your physician, adhering to both the dosage and treatment length. Ingest the entire tablet without chewing, crushing, or dividing it. Avazide MF 40mg/500mg Extended-Release Tablets should be taken with meals.

How Avazide MF 40mg/500mg Tablet SR works:

The extended-release tablet Avazide MF, containing 40mg of Gliclazide and 500mg of Metformin, offers a dual-action approach to diabetes management.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Combining Avazide MF 40mg/500mg SR tablets with alcohol is unsafe.

PregnancyPregnancyCONSULT YOUR DOCTOR

Use of Avazide MF 40mg/500mg SR tablets during pregnancy poses a confirmed risk to fetal development and is therefore inadvisable. Exceptions may exist in life-threatening circumstances where a physician deems the potential benefits outweigh the known hazards. Physician consultation is essential.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Extended-release Avazide MF 40mg/500mg tablets are likely unsafe for breastfeeding mothers. Available human data indicates potential drug transfer to breast milk, posing a risk to the infant.

DrivingDrivingCAUTION

Driving ability can be impaired by both hypoglycemia and hyperglycemia. Refrain from driving if you experience these conditions.

KidneyKidneyCAUTION

Patients with kidney impairment should use Avazide MF 40mg/500mg SR tablets cautiously, potentially requiring dosage modification. Severe kidney disease contraindicates the use of Avazide MF 40mg/500mg SR tablets. Medical supervision, including regular kidney function assessments, is recommended during treatment.

LiverLiverCAUTION

Patients with liver impairment should use Avazide MF 40mg/500mg SR tablets cautiously, potentially requiring dosage modification. A physician's consultation is advised. Individuals with mild to moderate liver disease should typically begin with a low dose; however, Avazide MF 40mg/500mg SR tablets are contraindicated in those with severe hepatic dysfunction.

What if you forget to take Avazide MF 40mg/500mg Tablet SR :

Should you forget to take a scheduled dose of your Avazide MF 40mg/500mg SR tablet, administer it immediately. Nevertheless, if your next dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Avazide MF 40mg/500mg Tablet SR

LabelValue
Potential for Dependence None.
Type of Treatment Medication for diabetes

FAQs on Avazide MF 40mg/500mg Tablet SR

The sustained-release tablet Avazide MF 40mg/500mg combines gliclazide and metformin to manage type 2 diabetes mellitus in adults. This medication helps regulate blood sugar when coupled with a healthy diet and regular physical activity. Gliclazide functions by stimulating insulin secretion from the pancreas, while metformin reduces hepatic glucose production and enhances insulin responsiveness. This dual-drug therapy is unsuitable for type 1 diabetes.
Avazide MF 40mg/500mg SR tablets are linked to several common adverse reactions. These include low blood sugar (hypoglycemia), changes in taste perception, nausea, abdominal pain, diarrhea, headache, and upper respiratory infections. Less frequent, though potentially serious, side effects such as lactic acidosis may occur. Prolonged use may also result in vitamin B12 deficiency.
Indeed, taking Avazide MF 40mg/500mg SR tablets may lead to hypoglycemia, characterized by low blood glucose. Manifestations of low blood sugar include nausea, headache, irritability, increased appetite, sweating, lightheadedness, tachycardia, and feelings of nervousness or tremor. This risk increases with skipped or delayed meals, alcohol consumption, excessive physical activity, or concomitant use of other antidiabetic medications. Consequently, consistent blood glucose monitoring is crucial. Carrying readily available glucose sources, such as glucose tablets, honey, or fruit juice, is recommended.
Indeed, taking Avazide MF 40mg/500mg Tablet SR carries a risk of lactic acidosis, a serious medical condition characterized by excessive lactic acid in the bloodstream. Also termed Metformin-associated lactic acidosis (MALA), this is an infrequent adverse reaction linked to metformin. Its occurrence is minimized by avoiding use in individuals with pre-existing kidney impairment, the elderly, or those consuming significant alcohol. Symptoms can manifest as muscle aches or weakness, vertigo, fatigue, cold extremities, respiratory distress, queasiness, emesis, abdominal discomfort, or bradycardia. Should any of these signs appear, discontinue Avazide MF 40mg/500mg Tablet SR and seek prompt medical attention.
Prolonged Avazide MF 40mg/500mg SR tablet use can indeed lead to vitamin B12 deficiency. This is because the medication impedes the stomach's absorption of vitamin B12. Left unaddressed, this deficiency may result in anemia, neurological complications such as tingling and numbness in the extremities, muscle weakness, urinary dysfunction, cognitive impairment, and gait instability. Preventive measures proposed by some studies involve supplemental vitamin B12 intake at least annually.
Patients with a history of hypersensitivity to Avazide MF 40mg/500mg Tablet SR components or inactive ingredients should not use this medication. Its use is also contraindicated in individuals with moderate to severe renal impairment or pre-existing metabolic acidosis, such as diabetic ketoacidosis.
Consuming alcohol concurrently with Avazide MF 40mg/500mg SR tablets is inadvisable. This combination may cause dangerously low blood sugar and heighten the risk of lactic acidosis.
The extended-release Avazide MF 40mg/500mg tablet combines gliclazide and metformin to manage type 2 diabetes mellitus in adults. This medication helps regulate blood sugar when used with a suitable diet and exercise regimen. Gliclazide enhances insulin secretion from the pancreas, reducing blood glucose. Metformin acts by decreasing hepatic glucose production and boosting insulin responsiveness. This formulation is unsuitable for treating type 1 diabetes.
Avazide MF 40mg/500mg SR tablets are linked to predictable adverse reactions. These include low blood glucose, taste disturbances, queasiness, abdominal discomfort, loose stools, cephalalgia, and upper respiratory infections. While infrequent, severe reactions such as lactic acidosis are possible. Prolonged treatment may also result in vitamin B12 insufficiency.
Avazide MF 40mg/500mg SR tablets may induce hypoglycemia (low blood glucose). Manifestations of low blood sugar can encompass nausea, headache, irritability, hunger, diaphoresis, vertigo, tachycardia, and feelings of anxiety or tremor. The risk increases with skipped or delayed meals, alcohol consumption, excessive physical activity, or concomitant use of other antidiabetic medications. Therefore, consistent blood glucose monitoring is crucial. Always carry readily available glucose sources, such as glucose tablets, honey, or fruit juice.
Indeed, Avazide MF 40mg/500mg Tablet SR carries a risk of lactic acidosis, a serious medical condition characterized by excessive blood lactic acid. This complication, also termed MALA (Metformin-associated lactic acidosis), is an infrequent adverse reaction to metformin. Its occurrence is minimized by avoiding use in individuals with pre-existing kidney impairment, the elderly, or those consuming substantial alcohol. Manifestations of lactic acidosis can encompass muscle aches or weakness, vertigo, fatigue, cold extremities, dyspnea, emesis, abdominal discomfort, and bradycardia. Should these symptoms arise, discontinue Avazide MF 40mg/500mg Tablet SR and seek immediate medical attention.
Prolonged use of Avazide MF 40mg/500mg Tablet SR can indeed lead to vitamin B12 deficiency. This is because the medication hinders the stomach's absorption of vitamin B12. Untreated deficiency may manifest as anemia, neurological issues including tingling, numbness in the extremities, weakness, urinary dysfunction, cognitive changes, and impaired balance. To mitigate these risks, supplemental vitamin B12 intake, at minimum annually, is recommended by some studies.
Patients with hypersensitivity to Avazide MF 40mg/500mg Tablet SR components or inactive ingredients should not use this medication. Its use is contraindicated in individuals with moderate to severe renal impairment or pre-existing metabolic acidosis, such as diabetic ketoacidosis.
Consuming alcohol while taking Avazide MF 40mg/500mg SR tablets is unsafe. This combination risks lowering blood glucose to dangerous levels (hypoglycemia) and elevates the likelihood of lactic acidosis.
Avazide MF 40mg/500mg Tab...
43
MRP 52
17% off