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Calcium Folinate Injection

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Fresenius Kabi India Pvt Ltd

Salt Composition

Calcium Leucovorin (15mg)

Overview Calcium Folinate Injection

Leucovorin injection counteracts the adverse effects of methotrexate, a cancer treatment drug, and manages methotrexate overdose. Administered intravenously at a slow rate under medical guidance, the dosage and frequency are determined by your physician based on your condition and may vary. Precise adherence to your doctor's instructions is vital, as improper use or excessive doses can lead to severe complications. Injection site inflammation, soreness, or redness are common, but should be reported if bothersome or severe; mitigation strategies exist. Blood tests monitoring blood cell counts and methotrexate levels are routine. Prior to treatment, disclose any history of seizures, liver or kidney disease, or use of infection-fighting medications. Interactions with other drugs, particularly anticonvulsants like phenytoin, are possible; inform your healthcare provider of all medications you are taking. Pregnant or breastfeeding patients should inform their physician before commencing treatment to ensure safety.

Uses of Calcium Folinate Injection

Mitigating Methotrexate-Induced Adverse Reactions

Major Benefits of Calcium Folinate Injection:

This medication will be administered by your healthcare provider; self-medication is strictly prohibited.

Common Side effects of Calcium Folinate Injection:

  • Injection site reactions (pain, swelling, redness)

How to use Calcium Folinate Injection:

The medication will be administered by your healthcare provider. Self-medication is strongly discouraged.

How Calcium Folinate Injection works:

Leucovorin injection, a vitamin B derivative, safeguards normal cells from methotrexate's (a cancer medication) harmful effects, enabling selective destruction of cancerous cells.

SAFETY ADVICE

AlcoholAlcoholCONSULT YOUR DOCTOR

Alcohol consumption alongside Calcium Folinate Injection may pose unknown risks. Seek medical advice before combining them.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Calcium Folinate Injection during pregnancy may pose risks. While human research is scant, animal studies indicate potential harm to the unborn child. A physician will assess the potential advantages against possible risks prior to prescription. Seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Data on Calcium Folinate Injection use while breastfeeding is lacking. Seek your physician's advice.

DrivingDrivingSAFE

Driving ability is typically unaffected by Calcium Folinate Injection.

KidneyKidneyCONSULT YOUR DOCTOR

Data regarding Calcium Folinate Injection's use in patients exhibiting renal impairment is scarce. Physician consultation is advised.

LiverLiverCONSULT YOUR DOCTOR

Data on Calcium Folinate Injection use in individuals with hepatic impairment is scarce. Physician consultation is advised.

What if you forget to take Calcium Folinate Injection :

Should you forget a Calcium Folinate Injection, administer it at your earliest convenience. If, however, your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Never take a double dose.

Facts to Know About Calcium Folinate Injection

LabelValue
Chemical Type Glutamate Derivatives
Developing Habits No.
Treatment Category KINSHIP
Actions Methotrexate as a cytoprotective agent

FAQs on Calcium Folinate Injection

Calcium Folinate Injection counteracts methotrexate's harmful side effects during cancer treatment. It also treats methotrexate overdose and similar medication overdoses. Furthermore, it addresses megaloblastic anemia resulting from folic acid deficiency when oral administration is impractical.
Anemia is a condition where the oxygen-carrying red blood cells are deficient, leading to insufficient oxygen delivery to tissues and organs. Megaloblastic anemia, a type of anemia, features abnormally large red blood cells and a reduced red blood cell count, typically resulting from vitamin B12 or folate deficiency. How quickly does Calcium Folinate Injection take effect?
Calcium folinate injection typically begins working within five minutes, although the onset may differ based on factors such as dosage and individual patient response.
To optimize your Calcium Folinate Injection treatment, your doctor will order blood tests. These include serum methotrexate level checks (for methotrexate chemotherapy or overdose) to determine the correct dose and duration, a complete blood count to monitor for megaloblastic anemia, and calcium level monitoring to prevent hypercalcemia, a risk due to the injection's calcium content.
Ensure urine output exceeds 2500 mL daily in adults, achieved by increasing oral or intravenous fluids 12 hours pre- and 36 hours post-methotrexate infusion. Monitor urine alkalinization (pH > 7.0) prior to methotrexate administration to optimize excretion. Avoid acidic foods, drinks, and medications throughout treatment. Post-infusion, measure serum methotrexate levels at 24, 48, and 72 hours.
Calcium Folinate Injectio...
115
MRP 133
13% off