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Calcium Folinate Injection

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Prescription Required

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Fresenius Kabi India Pvt Ltd

Salt Composition

Calcium Leucovorin (50mg)

Overview Calcium Folinate Injection

Leucovorin injection counteracts the adverse effects of methotrexate, a cancer treatment drug, and serves as an antidote for methotrexate overdose. Administered intravenously by a healthcare professional at a controlled rate, the dosage and frequency are determined by your physician based on your specific condition and may vary. Strict adherence to the prescribed regimen is crucial; incorrect usage or overdosage can lead to severe complications. Injection site inflammation (pain, swelling, redness) is a common side effect; report any concerning symptoms to your doctor for potential management strategies. Blood tests monitoring blood cell counts and methotrexate levels are essential. Prior to treatment, disclose any existing conditions such as seizures, liver or kidney impairment, or concurrent medication use, particularly anti-infectives. Inform your healthcare provider of all medications, including anticonvulsants like phenytoin, due to potential drug interactions. Pregnancy or breastfeeding should also be reported to ensure treatment safety.

Primary Ingredients of Calcium Folinate Injection

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Uses of Calcium Folinate Injection

Mitigating Methotrexate-Related Adverse Events

Major Benefits of Calcium Folinate Injection:

This medication will be administered by your physician or registered nurse; self-medication is strictly prohibited.

Common Side effects of Calcium Folinate Injection:

  • Injection site reactions (pain, swelling, redness)

How to use Calcium Folinate Injection:

This medication will be administered by your healthcare provider. Self-medication is strictly prohibited.

How Calcium Folinate Injection works:

Leucovorin injection, a vitamin B derivative, safeguards healthy cells from methotrexate's (a cancer treatment) harmful effects, while enabling the drug to selectively target and destroy cancerous tissue.

SAFETY ADVICE

AlcoholAlcoholCONSULT YOUR DOCTOR

Alcohol consumption alongside Calcium Folinate Injection may pose unknown safety risks. Seek medical advice before combining them.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Calcium Folinate Injection during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to a developing fetus. A physician will assess the advantages against potential dangers prior to prescription. Seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Data on Calcium Folinate Injection use while breastfeeding is lacking. Seek medical advice from your physician.

DrivingDrivingSAFE

Driving ability is typically unaffected by Calcium Folinate Injection.

KidneyKidneyCONSULT YOUR DOCTOR

Data regarding Calcium Folinate Injection use in individuals with renal impairment is scarce. Seek medical advice from your physician.

LiverLiverCONSULT YOUR DOCTOR

Data regarding Calcium Folinate Injection's use in individuals with hepatic impairment is scarce. Physician consultation is recommended.

What if you forget to take Calcium Folinate Injection :

Should you forget a Calcium Folinate Injection dose, administer it promptly. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Calcium Folinate Injection

LabelValue
Chemical Classification Glutamate Derivatives
Developing Habits No.
Treatment Category KINSHIP
Action Class Methotrexate as a cytoprotective agent

FAQs on Calcium Folinate Injection

Calcium Folinate Injection counteracts methotrexate's harmful side effects during cancer treatment. It also treats methotrexate overdose and similar medication overdoses. Additionally, it addresses megaloblastic anemia resulting from folic acid deficiency when oral medication is impractical.
Anemia is a condition where there's a lower-than-normal number of oxygen-carrying red blood cells (RBCs), depriving tissues and organs of sufficient oxygen. Megaloblastic anemia, a type of anemia, features abnormally large RBCs and a reduced RBC count, typically resulting from vitamin B12 or folic acid deficiency. How long does Calcium Folinate Injection take to work?
Calcium folinate injection typically takes effect within five minutes, although the onset may vary depending on factors such as dosage and individual patient response.
To optimize your Calcium Folinate Injection treatment, your doctor will order blood tests. These include serum methotrexate level checks (if you're receiving methotrexate chemotherapy or have overdosed) to determine the correct dosage and treatment length, a complete blood count to monitor red blood cell levels (especially if megaloblastic anemia is a concern), and calcium level monitoring to prevent hypercalcemia, given the calcium content of the injection.
Maintain urine output above 2500 mL/day in adults by increasing oral or intravenous fluids for 48 hours, starting 12 hours before methotrexate infusion. Ensure urinary pH remains above 7.0 prior to and during methotrexate infusion by avoiding acidic foods, drinks, and medications. Monitor methotrexate blood levels at 24, 48, and 72 hours post-infusion.
Calcium Folinate Injectio...
286
MRP 331
13% off