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Coxter 450mg/300mg Tablet

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Prescription Required

Marketer

Alkem Laboratories Ltd

Salt Composition

Rifampicin (450mg) + Isoniazid (300mg)

Overview Coxter 450mg/300mg Tablet

Tuberculosis treatment utilizes the combined medication, Coxter 450 mg/300 mg tablets. This prescription drug inhibits the growth of tuberculosis-causing bacteria. Always follow your physician's instructions; take on an empty stomach at the same time each day for optimal results. Exceeding the prescribed dosage can be harmful. Missed doses should be taken immediately upon recall. Complete the full course of treatment, even with symptom improvement; premature cessation may reduce effectiveness. Therapeutic effects may take time to manifest. Report any worsening symptoms or lack of improvement to your doctor. Common side effects include nausea, vomiting, fever, dark urine, sweating, hypersalivation, etc. Hydration is crucial to manage these effects; consult your doctor if they worsen. Serious side effects are uncommon. Seek immediate medical attention for allergic reactions (rash, itching, swelling, breathing difficulties). Inform your doctor of all other medications. Patients with liver or kidney disease require careful monitoring. Pregnant or breastfeeding individuals should consult their doctor before use. Alcohol consumption should be avoided due to potential drowsiness. While generally safe for driving, avoid driving if experiencing drowsiness or dizziness. Adequate rest and a healthy diet promote faster recovery. Your doctor may order lab tests to monitor the medication's effects.

Uses of Coxter 450mg/300mg Tablet

Managing Tuberculosis (TB) Infection

Major Benefits of Coxter 450mg/300mg Tablet:

Administer this medication precisely as directed by your physician, adhering to the prescribed dosage and treatment schedule. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Coxter 450 mg/300 mg tablets should be taken on an empty stomach. Refrain from consuming Coxter 450 mg/300 mg tablets with foods high in tyramine, including but not limited to cheese, cured meats, smoked fish, and certain beers.

Common Side effects of Coxter 450mg/300mg Tablet:

  • Dark colored urine
  • Rash
  • Vomiting
  • Jaundice
  • Fever
  • Increased liver enzymes
  • Nausea
  • Peripheral neuropathy (tingling and numbness of feet and hand)

How to use Coxter 450mg/300mg Tablet:

Administer this medication precisely as your physician directs, adhering to the prescribed dosage and treatment length. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Coxter 450 mg/300 mg tablets should be taken on an empty stomach. Refrain from consuming Coxter 450 mg/300 mg tablets concurrently with foods high in tyramine, including certain cheeses, smoked seafood, meats, and some beers.

How Coxter 450mg/300mg Tablet works:

Each Coxter 450 mg/300 mg tablet combines rifampicin and isoniazid, two antibiotics effective against tuberculosis. Rifampicin disables a crucial bacterial enzyme (RNA polymerase), halting the TB bacteria's protein synthesis and reproduction. Concurrently, isoniazid interferes with the bacteria's protective cell wall formation. This synergistic action eliminates the infection by destroying the tuberculosis bacteria.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Ingesting alcohol alongside Coxter 450 mg/300 mg Tablet can lead to side effects including facial redness, rapid pulse, queasiness, dehydration, pectoral discomfort, and hypotension (a Disulfiram-like reaction).

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Coxter 450 mg/300 mg tablets during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to the fetus. A physician will assess the potential advantages against any possible dangers prior to prescribing. Seek medical advice.

Breast feedingBreast feedingSAFE IF PRESCRIBED

Lactation compatibility studies indicate Coxter 450 mg/300 mg tablets pose minimal risk during breastfeeding. Research in humans shows negligible drug transfer into breast milk, presenting no apparent harm to the infant.

DrivingDrivingUNSAFE

Driving ability may be impaired by Coxter 450 mg/300 mg Tablets, which can induce seizures, psychiatric disorders, and optic neuritis (optic nerve inflammation potentially leading to vision loss).

KidneyKidneyCAUTION

Patients with kidney impairment should exercise caution when using Coxter 450 mg/300 mg tablets. Dosage modification may be necessary. Physician consultation is advised.

LiverLiverCAUTION

Patients with liver impairment should use Coxter 450 mg/300 mg tablets cautiously, potentially requiring a modified dosage. Physician consultation is advised. Coxter 450 mg/300 mg tablets are contraindicated in patients exhibiting severe hepatic dysfunction.

What if you forget to take Coxter 450mg/300mg Tablet :

Should you forget a Coxter 450 mg/300 mg Tablet dose, administer it promptly. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Coxter 450mg/300mg Tablet

LabelValue
Addictive None.
Treatment Category Drugs to combat infection

FAQs on Coxter 450mg/300mg Tablet

The combined medication Coxter 450 mg/300 mg, containing Rifampicin and Isoniazid, combats tuberculosis. Rifampicin's mechanism involves disabling a crucial bacterial enzyme (RNA polymerase), essential for tuberculosis bacteria to synthesize proteins and replicate. Isoniazid acts by hindering the formation of the protective layer surrounding tuberculosis bacteria. This dual action leads to bacterial eradication and disease resolution.
Complete the entire prescribed medication regimen. Do not discontinue prematurely, even if symptoms improve. Refrain from alcohol consumption during treatment, as it elevates the risk of liver injury. Report any visual disturbances, appetite loss, fatigue, abdominal pain, nausea, vomiting, jaundice, or dark urine to your physician immediately.
Administer Coxter 450 mg/300 mg tablets precisely as prescribed by your physician. Optimal absorption is achieved by ingestion on an empty stomach, at least one hour prior to or two hours following a meal.
Coxter 450 mg/300 mg tablets may cause a harmless discoloration of bodily fluids, including urine, skin, sweat, saliva, tears, and feces, resulting in a brownish-red or orange hue.
Coxter 450 mg/300 mg tablets can reduce the effectiveness of oral contraceptives. Therefore, consult your physician regarding alternative birth control options that don't rely on hormone regulation, like condoms, diaphragms, or spermicides.
Maintain this medication within its original, sealed container or packaging. Store as directed on the container or label. Discard any remaining medicine. Prevent access by children, pets, and others.
Coxter 450mg/300mg Tablet
43
MRP 52
17% off