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Duopil 1/500 Tablet PR

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Prescription Required

Marketer

Aristo Pharmaceuticals Pvt Ltd

Salt Composition

Glimepiride (1mg) + Metformin (500mg)

Overview Duopil 1/500 Tablet PR

Combipil, a dual-action antidiabetic medication, combines two agents to manage type 2 diabetes in adults. It effectively regulates blood glucose. Administer Combipil with meals, consistently at the same time daily for optimal results. Dosage is determined by your physician and may be adjusted based on your blood sugar response. Continuous use is crucial; discontinuation without medical consultation risks elevated blood sugar, potentially leading to kidney complications, vision impairment, neuropathy, and limb loss. This medication complements a comprehensive diabetes management plan, including a balanced diet, regular physical activity, and weight management as recommended by your doctor. Lifestyle choices significantly impact diabetes control. Hypoglycemia (low blood sugar) is a common side effect. Learn to identify symptoms—sweating, dizziness, headache, trembling—and how to treat them promptly. Maintain regular meals and carry a fast-acting glucose source (e.g., sugary foods, juice). Alcohol consumption increases hypoglycemia risk and should be minimized. Other potential side effects include altered taste, nausea, diarrhea, abdominal discomfort, headache, and upper respiratory infections. Weight gain may occur. Combipil is contraindicated in type 1 diabetes, diabetic ketoacidosis, and severe liver or kidney disease. Individuals with a history of heart disease should inform their physician before commencing treatment. Pregnant or lactating women should consult their doctor. Regular blood glucose monitoring, along with blood tests to assess blood cell counts and liver function, are essential.

Primary Ingredients of Duopil 1/500 Tablet PR

No text provided to rephrase.

Uses of Duopil 1/500 Tablet PR

Managing type 2 diabetes

Major Benefits of Duopil 1/500 Tablet PR:

Follow your doctor's instructions or consult the product label for guidance before administering. Consume Duopil 1/500 Tablet PR with a meal.

Common Side effects of Duopil 1/500 Tablet PR:

  • Headache
  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Diarrhea

How to use Duopil 1/500 Tablet PR:

Follow your physician's instructions or consult the product label for usage guidelines. Administer Duopil 1/500 Tablet PR with a meal.

How Duopil 1/500 Tablet PR works:

Duopil 1/500 PR tablets contain glimepiride and metformin, two medications used to manage diabetes. Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin, thus reducing blood sugar. Metformin, a biguanide, acts by decreasing liver glucose production, slowing intestinal glucose absorption, and enhancing insulin responsiveness.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Combining Duopil 1/500 Tablet PR with alcohol is inadvisable.

PregnancyPregnancyCONSULT YOUR DOCTOR

Using Duopil 1/500 Tablet PR during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to the fetus. A physician will assess the advantages against possible dangers prior to prescription. Seek medical advice.

Breast feedingBreast feedingUNSAFE

Using Duopil 1/500 Tablet PR while breastfeeding is contraindicated due to potential infant toxicity. Evidence indicates risk of harm to the nursing infant.

DrivingDrivingCAUTION

Impaired driving is possible with excessively low or high blood sugar levels. Refrain from driving if such symptoms arise.

KidneyKidneyCAUTION

Exercise caution when administering Duopil 1/500 Tablet PR to individuals with impaired renal function; dosage modification may be necessary. Consult a physician for guidance. Avoid using Duopil 1/500 Tablet PR in patients with severely compromised kidney function. Routine monitoring of kidney function is recommended during treatment.

LiverLiverCAUTION

Patients with liver impairment should use Duopil 1/500 Tablet PR cautiously, potentially requiring dosage modification. Consultation with a physician is advised. For those with mild to moderate liver disease, initiation should be at a low dose; it's contraindicated in cases of severe hepatic dysfunction.

What if you forget to take Duopil 1/500 Tablet PR :

Should you forget a Duopil 1/500 Tablet PR dose, administer it at your earliest convenience. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Duopil 1/500 Tablet PR

LabelValue
Developing Habits No.
Treatment Category Diabetes Management

FAQs on Duopil 1/500 Tablet PR

Store this medication in its original, tightly closed container as directed on the label. Discard any unused medication and keep it out of reach of children, pets, and others.
Duopil 1/500 Tablet PR can cause lactic acidosis, a serious medical emergency characterized by excessive blood lactic acid (also known as MALA or Metformin-associated lactic acidosis). This rare but potentially harmful side effect is more likely in patients with kidney disease, older adults, or those who consume large amounts of alcohol. Symptoms include muscle pain or weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If you experience these symptoms, discontinue Duopil 1/500 Tablet PR and seek immediate medical attention.
Duopil 1/500 Tablet PR combines glimepiride and metformin to manage type 2 diabetes mellitus (DM) in adults. This medication improves blood sugar control when used with diet and exercise. Glimepiride stimulates insulin release from the pancreas, while metformin reduces liver glucose production and enhances insulin sensitivity. It's not suitable for type 1 DM.
Duopil 1/500 Tablet PR may cause common side effects such as low blood sugar (hypoglycemia), altered taste, nausea, stomach pain, diarrhea, and headache. Rare but serious side effects include lactic acidosis. Prolonged use can result in vitamin B12 deficiency.
Prolonged use of Duopil 1/500 Tablet PR can lead to vitamin B12 deficiency by impairing its absorption in the stomach. This deficiency, if left untreated, may result in anemia, neurological issues such as tingling, numbness in the extremities, weakness, urinary problems, cognitive changes, and balance difficulties (ataxia). To mitigate this risk, annual supplementation with external vitamin B12 sources is recommended by some researchers.
Duopil 1/500 Tablet PR can cause low blood sugar (hypoglycemia), manifesting as nausea, headache, irritability, hunger, sweating, dizziness, rapid heart rate, anxiety, or shakiness. This risk increases with missed meals, alcohol consumption, excessive exercise, or concurrent use of other antidiabetic medications. Regular blood sugar monitoring is crucial. Always carry a fast-acting sugar source, such as glucose tablets, honey, or fruit juice.
Combining Duopil 1/500 Tablet PR with alcohol is unsafe. This combination can dangerously lower blood sugar (causing hypoglycemia) and raise the risk of lactic acidosis.
Duopil 1/500 Tablet PR
63
MRP 73
13% off