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Duopil 2/500 Tablet PR

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Prescription Required

Marketer

Aristo Pharmaceuticals Pvt Ltd

Salt Composition

Glimepiride (2mg) + Metformin (500mg)

Overview Duopil 2/500 Tablet PR

Combipil, a dual-action antidiabetic medication, combines two active agents to manage type 2 diabetes in adults. This formulation effectively regulates blood glucose levels. Always take Combipil with food, at the same time daily for optimal results. Dosage is determined by your physician and may be adjusted based on your blood sugar response. Continued use is crucial, even with controlled blood sugar, as abrupt cessation can lead to dangerously elevated glucose levels, potentially causing kidney complications, vision impairment, neuropathy, and limb loss. Combipil is only one component of a comprehensive diabetes management plan; a balanced diet, regular exercise, and weight management, as advised by your doctor, are equally vital. The most frequent adverse event is hypoglycemia (low blood sugar). Learn to identify its symptoms—sweating, dizziness, headache, and tremors—and how to treat them promptly. Maintain regular mealtimes and carry a readily available glucose source, such as sweets or juice. Alcohol consumption increases hypoglycemia risk and should be limited. Other potential side effects include altered taste, nausea, diarrhea, abdominal discomfort, headache, and upper respiratory infections. Weight gain may also occur. Combipil is contraindicated for type 1 diabetes, diabetic ketoacidosis, and severe hepatic or renal impairment. Prior heart disease should be disclosed to your physician before starting treatment. Consult your doctor before use during pregnancy or breastfeeding. Regular blood glucose monitoring is essential, and your doctor may order blood tests to assess blood cell counts and liver function.

Primary Ingredients of Duopil 2/500 Tablet PR

No information provided. Please provide the text you wish to be rewritten.

Uses of Duopil 2/500 Tablet PR

Managing type 2 diabetes

Major Benefits of Duopil 2/500 Tablet PR:

Follow your doctor's instructions or consult the product label for usage guidelines. Administer Duopil 2/500 Tablet PR with a meal.

Common Side effects of Duopil 2/500 Tablet PR:

  • Headache
  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Diarrhea

How to use Duopil 2/500 Tablet PR:

Follow your doctor's instructions or consult the product label for guidance. Take Duopil 2/500 Tablet PR with food.

How Duopil 2/500 Tablet PR works:

Duopil 2/500 PR tablets combine glimepiride and metformin, two distinct antidiabetic agents. Glimepiride, a sulfonylurea, stimulates pancreatic insulin secretion, thus reducing blood sugar. Metformin, a biguanide, acts by decreasing hepatic glucose production, retarding intestinal glucose uptake, and enhancing insulin responsiveness.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Combining Duopil 2/500 Tablet PR and alcohol is not advisable.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Duopil 2/500 Tablet PR during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to the unborn child. A physician will assess the advantages against possible risks prior to prescribing. Seek medical advice before taking this medication.

Breast feedingBreast feedingUNSAFE

The drug combination Duopil 2/500 Tablet PR is contraindicated for breastfeeding mothers due to potential infant toxicity.

DrivingDrivingCAUTION

Driving ability can be impaired by both hypoglycemia and hyperglycemia. Refrain from driving if you experience these conditions.

KidneyKidneyCAUTION

Patients with kidney impairment should use Duopil 2/500 Tablet PR cautiously, potentially requiring dosage modification. Severe kidney disease contraindicates its use. Physician consultation is recommended. Kidney function should be regularly monitored during treatment.

LiverLiverCAUTION

Patients with liver impairment should use Duopil 2/500 Tablet PR cautiously, potentially requiring dosage modification. A physician's consultation is advised. For those with mild to moderate liver disease, initiation is typically at a low dosage; however, it's contraindicated in patients with severe hepatic dysfunction.

What if you forget to take Duopil 2/500 Tablet PR :

Should you forget a Duopil 2/500 Tablet PR dose, administer it immediately. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Duopil 2/500 Tablet PR

LabelValue
Developing Habits No.
Type of Therapy Diabetes Management

FAQs on Duopil 2/500 Tablet PR

Store this medication in its original, tightly closed container, following the storage instructions on the label. Dispose of any unused medication properly and keep it out of reach of children, pets, and others.
Duopil 2/500 Tablet PR can cause lactic acidosis, a serious medical emergency characterized by excessive blood lactic acid (also known as MALA, or Metformin-associated lactic acidosis). This rare but potentially harmful side effect is more likely in patients with kidney disease, older adults, or those who consume large amounts of alcohol. Symptoms include muscle pain or weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and slow heart rate. If you experience these, discontinue Duopil 2/500 Tablet PR and seek immediate medical attention.
Duopil 2/500 Tablet PR combines glimepiride and metformin to manage type 2 diabetes mellitus (DM) in adults. This medication enhances blood glucose control when used with diet and exercise. Glimepiride stimulates insulin release from the pancreas, while metformin reduces liver glucose production and improves insulin sensitivity. It's not suitable for type 1 DM.
Duopil 2/500 Tablet PR may cause common side effects such as low blood sugar (hypoglycemia), altered taste, nausea, stomach pain, diarrhea, and headache. Rare but serious side effects include lactic acidosis. Prolonged use can result in vitamin B12 deficiency.
Prolonged use of Duopil 2/500 Tablet PR can lead to vitamin B12 deficiency by hindering its absorption in the stomach. This deficiency, if left untreated, may result in anemia, neurological issues such as tingling, numbness in extremities, weakness, urinary problems, cognitive changes, and ataxia. To mitigate this risk, supplemental vitamin B12 is recommended at least annually by some researchers.
Duopil 2/500 Tablet PR can indeed cause low blood sugar (hypoglycemia), manifesting as nausea, headache, irritability, hunger, sweating, dizziness, rapid heart rate, anxiety, or shakiness. This risk increases with missed meals, alcohol consumption, excessive exercise, or concomitant use of other antidiabetic medications. Therefore, regular blood sugar monitoring is crucial. Carry a fast-acting sugar source, such as glucose tablets, honey, or fruit juice, at all times.
Combining Duopil 2/500 Tablet PR with alcohol is unsafe. This combination can cause dangerously low blood sugar (hypoglycemia) and raise the risk of lactic acidosis.
Duopil 2/500 Tablet PR
86
MRP 100
13% off