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Duotrol 2.5mg/500mg Tablet SR

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Prescription Required

Marketer

USV Ltd

Salt Composition

Glibenclamide (2.5mg) + Metformin (500mg)

Overview Duotrol 2.5mg/500mg Tablet SR

Glycemia-Control 2.5mg/500mg Extended-Release Tablets are classified as antidiabetic medications. This dual-action formulation treats type 2 diabetes in adults by managing blood glucose levels. Administer these tablets with food, consistently at the same time daily for optimal efficacy. Dosage is determined by your physician and may be adjusted based on your glycemic response. Continuous use is crucial, even with well-controlled blood sugar, as abrupt cessation can lead to elevated glucose, potentially causing kidney complications, vision impairment, neuropathy, and limb loss. This medication is one component of a comprehensive diabetes management plan, encompassing a healthy diet, regular exercise, and weight management as directed by your doctor. Lifestyle modifications significantly impact diabetes control. Hypoglycemia (low blood sugar) is a common adverse effect, characterized by sweating, dizziness, headache, and tremors. Learn to recognize and treat these symptoms; maintain regular meals and carry readily-available glucose sources, like sugary snacks or juice. Alcohol consumption elevates hypoglycemia risk and should be limited. Additional potential side effects include nausea, diarrhea, abdominal discomfort, headache, and upper respiratory infections. Weight gain is also possible. This medication is contraindicated for type 1 diabetes, diabetic ketoacidosis, and severe hepatic or renal impairment. Disclose any history of heart disease to your physician prior to use, as it may be unsuitable. Pregnant or breastfeeding individuals should consult their doctor before initiating treatment. Regular blood glucose monitoring and periodic blood tests to assess blood cell counts and liver function are recommended.

Primary Ingredients of Duotrol 2.5mg/500mg Tablet SR

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Uses of Duotrol 2.5mg/500mg Tablet SR

Non-insulin-dependent diabetes

Major Benefits of Duotrol 2.5mg/500mg Tablet SR:

Follow your doctor's instructions precisely regarding dosage and treatment length for this medication. Ingest the Duotrol 2.5mg/500mg SR tablet whole; avoid crushing, chewing, or breaking it. Administer this medication with a meal.

Common Side effects of Duotrol 2.5mg/500mg Tablet SR:

  • Dizziness
  • Diarrhea
  • Nausea
  • Flatulence
  • Headache
  • Upper respiratory tract infection

How to use Duotrol 2.5mg/500mg Tablet SR:

Consume this medication precisely as prescribed by your physician, adhering to the specified dosage and treatment period. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. The Duotrol 2.5mg/500mg extended-release tablet should be administered with a meal.

How Duotrol 2.5mg/500mg Tablet SR works:

Glibenclamide, a sulfonylurea drug, stimulates pancreatic insulin secretion to reduce blood sugar levels. Metformin, a biguanide, acts by decreasing hepatic glucose production, slowing intestinal glucose uptake, and enhancing insulin sensitivity.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Consuming alcohol alongside Duotrol 2.5mg/500mg SR tablets is inadvisable.

PregnancyPregnancySAFE IF PRESCRIBED

Extended-release Duotrol tablets (2.5mg/500mg) are typically deemed safe for use during gestation. Preclinical trials in animals revealed minimal or no negative impacts on fetal development; nevertheless, clinical data from human trials are scarce.

Breast feedingBreast feedingCAUTION

Extended-release Duotrol tablets (2.5mg/500mg) require careful consideration during lactation. Breastfeeding is advised against until maternal treatment concludes and the medication is fully cleared from the mother's system.

DrivingDrivingCONSULT YOUR DOCTOR

The effect of Duotrol 2.5mg/500mg Tablet SR on driving ability is undetermined. Refrain from driving if you experience symptoms impairing concentration or reaction time.

KidneyKidneyUNSAFE

Patients with kidney disease should likely avoid Duotrol 2.5mg/500mg SR tablets, as their use may be unsafe. A physician's consultation is recommended.

LiverLiverCAUTION

Patients with hepatic impairment should use Duotrol 2.5mg/500mg sustained-release tablets cautiously; dosage modification may be necessary. Physician consultation is advised.

What if you forget to take Duotrol 2.5mg/500mg Tablet SR :

Should you forget a Duotrol 2.5mg/500mg extended-release tablet, administer it promptly. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Duotrol 2.5mg/500mg Tablet SR

LabelValue
Developing Habits No.
Treatment Category Diabetes Management

FAQs on Duotrol 2.5mg/500mg Tablet SR

Duotrol SR 2.5mg/500mg tablets combine glibenclamide and metformin to manage type 2 diabetes mellitus in adults. This combination improves blood glucose control when used with diet and exercise. Glibenclamide stimulates insulin release from the pancreas, while metformin reduces liver glucose production and enhances insulin sensitivity. It's not suitable for type 1 diabetes.
Type 2 diabetes, the most prevalent form of diabetes, arises from the body's inability to produce sufficient insulin or utilize the insulin it does produce effectively. This leads to elevated blood glucose, causing serious health issues. High blood sugar symptoms include excessive urination, thirst, and hunger. Untreated, type 2 diabetes can result in long-term complications such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), foot problems, and an increased risk of heart disease.
Duotrol 2.5mg/500mg SR Tablets may cause common side effects such as hypoglycemia, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects, including lactic acidosis, are also possible. Prolonged use may result in vitamin B12 deficiency.
Duotrol 2.5mg/500mg SR tablets can cause low blood sugar (hypoglycemia), manifesting as nausea, headache, irritability, hunger, sweating, dizziness, rapid heartbeat, anxiety, or shakiness. This risk increases with skipped meals, alcohol consumption, excessive exercise, or concurrent use of other antidiabetic medications. Regular blood sugar monitoring is crucial. Always carry a fast-acting sugar source, such as glucose tablets, honey, or fruit juice.
Prolonged use of Duotrol 2.5mg/500mg SR tablets can interfere with vitamin B12 absorption, potentially leading to deficiency. This deficiency, if left untreated, may manifest as anemia, neurological issues such as numbness and tingling in the extremities, weakness, urinary problems, cognitive changes, and balance difficulties (ataxia). To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Patients with allergies to Duotrol 2.5mg/500mg Tablet SR components or excipients, moderate-to-severe kidney disease, or underlying metabolic acidosis (including diabetic ketoacidosis) should not use this medication.
Combining Duotrol 2.5mg/500mg SR tablets with alcohol is unsafe. This combination can cause dangerously low blood sugar (hypoglycemia) and raise the risk of lactic acidosis.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication and keep it out of reach of children, pets, and others.
Duotrol 2.5mg/500mg SR tablets combine glibenclamide and metformin to manage type 2 diabetes mellitus (DM) in adults. This medication improves blood glucose control when used with diet and exercise. Glibenclamide stimulates insulin release from the pancreas, while metformin reduces liver glucose production and enhances insulin sensitivity. It is not suitable for type 1 DM.
Type 2 diabetes, the most prevalent form of diabetes, arises from the body's inability to produce sufficient insulin or utilize it effectively. This insulin resistance leads to elevated blood glucose, causing serious health consequences. Symptoms include excessive urination, thirst, and hunger. Untreated, type 2 diabetes can result in long-term complications such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), foot problems, and increased risk of heart disease.
Duotrol 2.5mg/500mg SR tablets may cause common side effects such as low blood sugar, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use may also result in vitamin B12 deficiency.
Duotrol 2.5mg/500mg SR tablets can cause low blood sugar (hypoglycemia), manifesting as nausea, headache, irritability, hunger, sweating, dizziness, rapid heartbeat, anxiety, or shakiness. This risk increases with missed meals, alcohol consumption, excessive exercise, or concurrent use of other antidiabetic medications. Regular blood sugar monitoring is crucial. Always carry a fast-acting sugar source, such as glucose tablets, honey, or fruit juice.
Prolonged use of Duotrol 2.5mg/500mg SR tablets can interfere with vitamin B12 absorption, potentially leading to deficiency. This deficiency, if left untreated, may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, and ataxia), urinary issues, and cognitive changes. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Patients with known allergies to Duotrol 2.5mg/500mg Tablet SR components or excipients, moderate-to-severe kidney disease, or underlying metabolic acidosis (including diabetic ketoacidosis) should not use this medication.
Combining Duotrol 2.5mg/500mg SR tablets with alcohol is unsafe. Alcohol can worsen hypoglycemia and raise the risk of lactic acidosis.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication and keep it out of reach of children, pets, and others.
Duotrol 2.5mg/500mg Table...
38
MRP 45
14% off