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Duotrol-SR Tablet

Prescription Icon
Prescription Required

Marketer

USV Ltd

Salt Composition

Glibenclamide (5mg) + Metformin (500mg)

Overview Duotrol-SR Tablet

Glycemia-Duo XR tablets are classified as antidiabetic medications. This dual-action formulation treats type 2 diabetes in adults by managing blood glucose levels. Always take Glycemia-Duo XR with food, consistently at the same time daily for optimal effectiveness. Dosage is determined and adjusted by your physician based on your blood sugar response. Continuous use is crucial; discontinuation without medical consultation risks elevated blood sugar, potentially leading to kidney complications, vision impairment, neuropathy, and limb loss. Remember, this medication complements a comprehensive diabetes management plan encompassing diet, exercise, and weight management as directed by your doctor. Lifestyle choices significantly influence diabetes control. Hypoglycemia (low blood sugar) is a common side effect, characterized by symptoms like sweating, dizziness, headache, and tremors. Learn to recognize and treat these symptoms; maintain regular mealtimes and carry a fast-acting glucose source. Alcohol consumption elevates hypoglycemia risk and should be avoided. Additional potential side effects include nausea, diarrhea, abdominal pain, headache, and upper respiratory infections. Weight gain is also possible. This medication is contraindicated for type 1 diabetes, diabetic ketoacidosis, and severe hepatic or renal impairment. Inform your physician of any history of heart disease before commencing treatment; it may be unsuitable. Pregnant or lactating individuals should seek medical advice prior to use. Regular blood glucose monitoring is essential, and your doctor may order blood tests to track blood cell counts and liver function.

Primary Ingredients of Duotrol-SR Tablet

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Uses of Duotrol-SR Tablet

Adult-onset diabetes

Major Benefits of Duotrol-SR Tablet:

Consume this medication precisely as your physician directs, adhering to both the prescribed dosage and duration. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. For optimal absorption, administer Duotrol-SR with a meal.

Common Side effects of Duotrol-SR Tablet:

  • Dizziness
  • Diarrhea
  • Nausea
  • Flatulence
  • Headache
  • Upper respiratory tract infection

How to use Duotrol-SR Tablet:

Consume this medication precisely as your physician directs, adhering to the prescribed dosage and timeframe. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. It's recommended to take Duotrol-SR with a meal.

How Duotrol-SR Tablet works:

Glibenclamide, a sulfonylurea agent, stimulates pancreatic insulin secretion to reduce circulating blood glucose levels. Metformin, a biguanide, acts by decreasing hepatic glucose output, retarding intestinal glucose uptake, and enhancing insulin responsiveness in peripheral tissues.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Avoid alcohol while taking Duotrol-SR tablets.

PregnancyPregnancySAFE IF PRESCRIBED

Extended-release Duotrol tablets are typically deemed safe for use during gestation. Preclinical trials in animals revealed minimal or no negative consequences for fetal development; nonetheless, clinical data from human trials are scarce.

Breast feedingBreast feedingCAUTION

Extended-release Duotrol tablets require careful consideration when breastfeeding. Mothers should discontinue breastfeeding throughout their treatment course and until the medication is fully cleared from their system.

DrivingDrivingCONSULT YOUR DOCTOR

The effect of Duotrol-SR Tablet on driving ability is undetermined. Refrain from driving if experiencing symptoms impairing concentration or reaction time.

KidneyKidneyUNSAFE

Patients with kidney disease should likely avoid Duotrol-SR Tablets due to potential safety concerns. A physician's consultation is recommended.

LiverLiverCAUTION

Patients with hepatic impairment should exercise caution when using Duotrol-SR Tablets. Dosage modification may be necessary. Physician consultation is advised.

What if you forget to take Duotrol-SR Tablet :

Should you forget a Duotrol-SR Tablet dose, administer it promptly. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Duotrol-SR Tablet

LabelValue
Developing Habits No.
Treatment Category Diabetes Treatment

FAQs on Duotrol-SR Tablet

Duotrol-SR tablets combine glibenclamide and metformin to manage type 2 diabetes mellitus in adults. This combination improves blood glucose control when used with diet and exercise. Glibenclamide stimulates insulin release from the pancreas, while metformin reduces liver glucose production and enhances insulin sensitivity. It's not suitable for type 1 diabetes.
Type 2 diabetes, the most prevalent form of diabetes, arises from the body's inability to produce sufficient insulin or utilize the insulin it does produce effectively. This leads to elevated blood glucose, causing symptoms like frequent urination, excessive thirst, and increased hunger. Untreated, type 2 diabetes can result in serious long-term complications including nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), foot problems, and an increased risk of heart disease.
Duotrol-SR Tablets may cause common side effects such as hypoglycemia, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use may result in vitamin B12 deficiency.
Duotrol-SR Tablets can cause low blood sugar (hypoglycemia), manifesting as nausea, headache, irritability, hunger, sweating, dizziness, rapid heartbeat, anxiety, or shakiness. This risk increases with missed meals, alcohol consumption, excessive exercise, or concurrent use of other antidiabetic medications. Regular blood sugar monitoring is crucial. Carry a fast-acting sugar source, such as glucose tablets, honey, or fruit juice, at all times.
Prolonged use of Duotrol-SR Tablets can interfere with vitamin B12 absorption, potentially leading to deficiency. This deficiency, if left untreated, may cause anemia, nerve damage (manifested as tingling, numbness in extremities, weakness, and ataxia), urinary issues, and cognitive changes. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Patients with known allergies to Duotrol-SR Tablet components or excipients, moderate-to-severe kidney disease, or underlying metabolic acidosis (including diabetic ketoacidosis) should not use this medication.
Combining Duotrol-SR Tablets and alcohol is unsafe. This combination can worsen low blood sugar and raise the risk of lactic acidosis.
Store this medication in its original, tightly closed container, as directed on the label or packaging. Discard any unused medication and keep it out of reach of children, pets, and others.
Duotrol-SR tablets combine glibenclamide and metformin to manage type 2 diabetes mellitus in adults. This combination improves blood glucose control when used with diet and exercise. Glibenclamide stimulates insulin release from the pancreas, while metformin reduces liver glucose production and enhances insulin sensitivity. Duotrol-SR is not suitable for type 1 diabetes.
Type 2 diabetes, the most prevalent form of diabetes, arises from the body's inability to produce sufficient insulin or utilize existing insulin effectively. This leads to elevated blood glucose, causing serious health consequences. High blood sugar manifests as increased urination, thirst, and hunger. Untreated, type 2 diabetes can result in long-term complications such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), foot problems, and an increased risk of heart disease.
Duotrol-SR Tablet may cause common side effects such as hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use may result in vitamin B12 deficiency.
Duotrol-SR Tablets can cause hypoglycemia (low blood sugar). Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, rapid heartbeat, and shakiness or anxiety. Hypoglycemia risk increases with missed meals, alcohol consumption, excessive exercise, or concurrent use of other antidiabetic medications. Regular blood sugar monitoring is crucial. Carry a fast-acting sugar source, such as glucose tablets, honey, or fruit juice, at all times.
Prolonged Duotrol-SR Tablet use can interfere with vitamin B12 absorption, potentially causing a deficiency. This deficiency, if left untreated, may lead to anemia, nerve damage (including tingling, numbness in extremities, weakness), urinary issues, cognitive changes, and ataxia. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Duotrol-SR Tablets are contraindicated in patients with allergies to any ingredient or excipient. They should not be used by individuals with moderate to severe kidney disease or those with metabolic acidosis, including diabetic ketoacidosis.
Combining Duotrol-SR Tablets and alcohol is unsafe due to the risk of dangerously low blood sugar (hypoglycemia) and increased lactic acidosis.
Store this medication in its original, tightly closed container, as directed on the label. Discard any unused medication and ensure it's inaccessible to children, pets, and others.
Duotrol-SR Tablet
56
MRP 65
13% off