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Entinib 400mg Tablet

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Enrico Pharmaceuticals

Salt Composition

Imatinib mesylate (400mg)

Overview Entinib 400mg Tablet

Imatinib 400mg tablets are indicated for various cancers. Primarily, they treat hematologic malignancies such as chronic myeloid leukemia and acute lymphoblastic leukemia, along with gastrointestinal stromal tumors. Its mechanism involves targeting proteins crucial for cancer cell proliferation and metastasis. This medication also addresses dermatofibrosarcoma protuberans and aggressive systemic mastocytosis. Administer with food, consistently at the same time daily for optimal efficacy. Continue treatment as directed by your physician; duration is individualized based on response and clinical need. Incorrect or excessive dosage may lead to severe adverse events. Therapeutic benefits may take weeks or months to manifest; discontinue only under medical supervision. Frequent side effects include swelling, nausea, vomiting, muscle spasms, musculoskeletal discomfort, diarrhea, skin rashes, tiredness, and stomach pain. Report sudden, significant weight increase immediately. Regular blood counts and liver function tests are often recommended. Avoid activities requiring alertness if dizziness or blurred vision occur. Inform your healthcare provider of all concurrent medications, as interactions are possible. This medicine is contraindicated during pregnancy and lactation; reliable contraception is essential for both partners throughout treatment.

Uses of Entinib 400mg Tablet

Oncological Management

Major Benefits of Entinib 400mg Tablet:

Consume this medication precisely as prescribed by your physician, adhering to both the dosage and treatment length. Ingest the entire tablet; avoid chewing, crushing, or fracturing it. The Entinib 400mg Tablet should be administered with a meal.

Common Side effects of Entinib 400mg Tablet:

  • Edema (swelling)
  • Nausea
  • Vomiting
  • Muscle cramp
  • Musculoskeletal (bone, muscle or joint) pain
  • Diarrhea
  • Rash
  • Fatigue
  • Abdominal pain
  • Bleeding
  • Breathing problems
  • Cough
  • Weight gain
  • Dry eye
  • Dizziness
  • Hemorrhage

How to use Entinib 400mg Tablet:

Consume this medication precisely as prescribed by your physician, adhering to both the dosage and treatment schedule. Ingest the entire tablet; avoid chewing, crushing, or fracturing it. The Entinib 400mg Tablet should be administered with a meal.

How Entinib 400mg Tablet works:

Entinib 400mg tablets are an anti-cancer drug targeting the bcr-abl tyrosine kinase enzyme. This enzyme drives uncontrolled growth in certain cancer cells. By inhibiting this enzyme, Entinib prevents cancerous cell multiplication and triggers programmed cell death in bcr-abl-positive cancers, thus hindering or halting disease progression.

SAFETY ADVICE

AlcoholAlcoholCONSULT YOUR DOCTOR

Alcohol consumption alongside Entinib 400mg Tablet may pose unknown risks. Seek medical advice before combining them.

PregnancyPregnancyCONSULT YOUR DOCTOR

Use of Entinib 400mg tablets is contraindicated during pregnancy due to established risks to fetal development. In exceptional, life-threatening circumstances, a physician might prescribe it if the potential benefits outweigh the known hazards. Always seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

The use of 400mg Entinib tablets while breastfeeding is likely unsafe. Available human data indicates potential transfer of the medication into breast milk, posing a risk to the infant. Breastfeeding should be discontinued during Entinib treatment and for a further 15 days post-treatment.

DrivingDrivingUNSAFE

Taking a 400mg Entinib tablet may impair driving ability due to potential adverse effects.

KidneyKidneyCAUTION

Patients with kidney impairment should use the 400mg Entinib tablet cautiously. Dosage modification may be necessary; physician consultation is advised.

LiverLiverCAUTION

Patients with severe hepatic impairment should use 400mg Entinib tablets cautiously. Dosage modification may be necessary; physician consultation is advised.

What if you forget to take Entinib 400mg Tablet :

Omit any missed Entinib 400mg Tablet dose and resume your usual medication regimen. Avoid taking a double dose.

Facts to Know About Entinib 400mg Tablet

LabelValue
Chemical Type Benzanilide Derivative
Developing Habits No.
Treatment Category Cancer Medications
Action Class Kinase inhibitors targeting tyrosine

FAQs on Entinib 400mg Tablet

For optimal absorption and to minimize stomach upset, take with food and a glass of water. If swallowing the tablet is difficult, dissolve it in 50ml of water or apple juice (for 100mg tablets) or 200ml (for 400mg tablets). Stir thoroughly and consume immediately.
Entinib 400mg tablets may cause dizziness, lightheadedness, or drowsiness. Drive or operate machinery only after you understand how this medication affects you.
Strictly adhere to your doctor's instructions and attend all scheduled appointments while taking Entinib 400mg Tablets. Regular monitoring, including blood, urine, and weight checks, is crucial to detect any side effects promptly. Use contraception throughout treatment and immediately inform your doctor if pregnancy occurs. Always inform your doctor about Entinib 400mg Tablet use before starting any new medication.
This medication can significantly increase your skin's sun sensitivity, potentially leading to rash, itching, redness, or severe sunburn. Always wear protective clothing and a sunscreen with SPF 15 or higher when outdoors. Report any burning sensation to your doctor immediately.
Entinib 400mg Tablet interacts with many medications, such as paracetamol, cyclosporin, dexamethasone, warfarin, antivirals (including those for AIDS), and drugs for bacterial infections, high cholesterol, high blood pressure, heart conditions, mental health disorders, and depression. Avoid self-medicating while taking Entinib 400mg Tablet. Always consult your doctor before starting any new medication and inform them you're using Entinib 400mg Tablet.
Entinib 400mg tablets have shown effectiveness in treating many Chronic Myelogenous Leukemia (CML) cases, often improving survival rates. Your doctor, considering your condition, blood work, treatment response, and other health factors, can best determine if this medication is right for you.
Entinib 400mg Tablet
1,836
MRP 2,130
13% off