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Glimibose-M1 Tablet PR

Prescription Icon
Prescription Required

Marketer

B.J.Healthcare

Salt Composition

Glimepiride (1mg) + Metformin (500mg)

Overview Glimibose-M1 Tablet PR

Combiprep-DM, a dual-action antidiabetic medication, manages type 2 diabetes in adults. This formulation combines two agents to regulate blood glucose. Always take Combiprep-DM with meals, consistently at the same time daily for optimal effectiveness. Dosage is determined by your physician and may be adjusted based on your blood glucose response. Continuous use is crucial; discontinuation without medical supervision can elevate blood sugar, increasing the risk of complications like nephropathy, retinopathy, neuropathy, and limb loss. Combiprep-DM is part of a comprehensive diabetes management plan encompassing a balanced diet, regular physical activity, and weight management as directed by your doctor. Lifestyle modifications are vital for diabetes control. Hypoglycemia (low blood sugar) is a common side effect, characterized by sweating, dizziness, headache, and tremors. Regular meals and readily available glucose sources (e.g., sugary snacks, juice) are essential to mitigate this risk. Alcohol consumption should be limited due to its potential to exacerbate hypoglycemia. Additional possible side effects include altered taste, nausea, diarrhea, abdominal discomfort, headache, and upper respiratory infections. Weight gain may also occur. Combiprep-DM is contraindicated in type 1 diabetes, diabetic ketoacidosis, and severe hepatic or renal impairment. Individuals with a history of heart disease should inform their doctor before starting this medication. Pregnant or lactating women require medical consultation prior to use. Regular blood glucose monitoring and periodic blood tests (to check blood cell counts and liver function) are recommended.

Uses of Glimibose-M1 Tablet PR

Managing type 2 diabetes

Major Benefits of Glimibose-M1 Tablet PR:

Follow your physician's instructions or consult the product information leaflet for dosage guidance. Administer Glimibose-M1 Tablet PR with meals.

Common Side effects of Glimibose-M1 Tablet PR:

  • Headache
  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Diarrhea

How to use Glimibose-M1 Tablet PR:

Follow your physician's instructions or consult the product label for proper administration. Take Glimibose-M1 Tablet PR with meals.

How Glimibose-M1 Tablet PR works:

Glimibose-M1 PR tablets contain glimepiride and metformin, two antidiabetic agents. Glimepiride, a sulfonylurea, stimulates pancreatic insulin secretion to reduce blood sugar. Metformin, a biguanide, acts by decreasing hepatic glucose production, inhibiting intestinal glucose absorption, and enhancing insulin sensitivity.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Combining Glimibose-M1 Tablet PR and alcohol poses a significant safety risk.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Glimibose-M1 Tablet PR during pregnancy may pose risks. While human research is scarce, animal studies indicate potential harm to the unborn child. A physician will assess the potential advantages against any possible risks prior to prescribing. Seek medical advice.

Breast feedingBreast feedingUNSAFE

Lactation and Glimibose-M1 Tablet PR are incompatible; evidence indicates potential infant harm from this medication.

DrivingDrivingCAUTION

Driving ability can be impaired by both hypoglycemia and hyperglycemia. Refrain from driving if you experience these conditions.

KidneyKidneyCAUTION

Patients with kidney impairment should use Glimibose-M1 Tablet PR cautiously, potentially requiring dose modification. Severe kidney disease contraindicates its use. Consult your physician. Regular kidney function monitoring is recommended during treatment.

LiverLiverCAUTION

Individuals with liver impairment should use Glimibose-M1 Tablet PR cautiously, potentially requiring dosage modification. Consultation with a physician is advised. For those with mild to moderate liver disease, Glimibose-M1 Tablet PR is typically initiated at a low dose; however, it's contraindicated in patients with severe liver dysfunction.

What if you forget to take Glimibose-M1 Tablet PR :

Should you forget a Glimibose-M1 Tablet PR dose, administer it at your earliest convenience. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Glimibose-M1 Tablet PR

LabelValue
Potential for Dependence None.
Type of Medication Medication for diabetes

FAQs on Glimibose-M1 Tablet PR

Store the medication in its original, tightly sealed container or packaging, following the storage instructions provided. Discard any remaining medication. Prevent access by children, pets, and other individuals.
Glimibose-M1 Tablet PR use can result in lactic acidosis, a serious medical condition characterized by excessive blood lactic acid. Also termed Metformin-associated lactic acidosis (MALA), this rare but potentially harmful side effect is particularly risky for individuals with kidney impairment, the elderly, or those who consume significant alcohol. Symptoms might involve muscle aches or weakness, vertigo, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, or bradycardia. Should these symptoms appear, discontinue Glimibose-M1 Tablet PR and seek immediate medical attention.
Glimibose-M1 Tablet PR, a dual-action formulation containing glimepiride and metformin, manages type 2 diabetes mellitus (DM) in adults. Its efficacy relies on the synergistic effects of these components, coupled with dietary adjustments and physical activity, to regulate blood glucose. Glimepiride stimulates pancreatic insulin secretion, reducing blood sugar. Concurrently, metformin reduces hepatic glucose output and enhances insulin responsiveness. This medication is unsuitable for type 1 DM.
Glimibose-M1 Tablet PR may cause common side effects including low blood sugar (hypoglycemia), taste disturbances, nausea, abdominal pain, diarrhea, and headaches. Rare but serious adverse reactions such as lactic acidosis are also possible. Prolonged use can result in vitamin B12 deficiency.
Prolonged Glimibose-M1 Tablet PR use can indeed lead to Vitamin B12 deficiency by hindering its intestinal absorption. This deficiency, if left unaddressed, may result in anemia, neurological complications such as paresthesia in the extremities, generalized weakness, urinary dysfunction, cognitive changes, and gait instability. Preventive measures, proposed by some studies, include annual supplemental Vitamin B12 administration.
Indeed, Glimibose-M1 Tablet PR can induce hypoglycemia. Manifestations of low blood sugar include nausea, headache, irritability, hunger pangs, sweating, vertigo, tachycardia, and feelings of anxiety or tremor. The likelihood increases with skipped or delayed meals, alcohol consumption, excessive physical activity, or concomitant use of other antidiabetic agents. Consequently, consistent blood glucose monitoring is crucial. It's advisable to carry a readily available fast-acting carbohydrate source such as glucose tablets, honey, or fruit juice.
Combining Glimibose-M1 Tablet PR and alcohol is unsafe due to the risk of significantly reduced blood glucose, potentially causing hypoglycemia. Furthermore, this combination elevates the likelihood of lactic acidosis.
Glimibose-M1 Tablet PR
49
MRP 60
18% off