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Glura M 100mg/1000mg Tablet XR

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Prescription Required

Marketer

Eris Lifesciences Ltd

Salt Composition

Sitagliptin (100mg) + Metformin (1000mg)

Overview Glura M 100mg/1000mg Tablet XR

Metformin/Glimepiride extended-release tablets (100mg/1000mg) manage elevated blood glucose in type 2 diabetes patients. This dual-action medication mitigates severe diabetic complications like renal impairment and vision loss, potentially lowering cardiovascular event risk. It can be used independently or in conjunction with other antidiabetic therapies. Optimal results require adherence to a balanced diet and consistent exercise. Dosage is individualized based on your health status, glucose levels, and concurrent medications. Consuming it with food minimizes gastrointestinal distress. Consistent daily dosing, at the same time, maximizes efficacy; discontinuation should only occur under physician guidance. Continued dietary and exercise adherence, as directed, is crucial for diabetes control. Common side effects include nausea, vomiting, diarrhea, stomach upset, headache, and pharyngitis. Hypoglycemia is a potential adverse effect, particularly when combined with insulin or sulfonylureas; appropriate management strategies should be understood. This medication is not universally suitable. Prior to commencing treatment, inform your doctor of any existing kidney, liver, heart, or pancreatic conditions, as well as significant alcohol consumption. Pregnant or lactating individuals should consult their physician. Interaction with other medications is possible; disclose all medications to ensure safety. Alcohol should be limited due to its hypoglycemic effects. Your physician will monitor renal function and glucose levels throughout treatment.

Primary Ingredients of Glura M 100mg/1000mg Tablet XR

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Uses of Glura M 100mg/1000mg Tablet XR

Managing type 2 diabetes

Major Benefits of Glura M 100mg/1000mg Tablet XR:

Follow your doctor's instructions precisely regarding dosage and treatment length for Glura M 100mg/1000mg Extended-Release Tablets. Ingest the tablet whole; avoid crushing, chewing, or breaking it. Administer this medication with food.

Common Side effects of Glura M 100mg/1000mg Tablet XR:

  • Decreased appetite
  • Vomiting
  • Upper respiratory tract infection
  • Hypoglycemia (low blood glucose level)
  • Abdominal bloating
  • Nausea
  • Diarrhea

How to use Glura M 100mg/1000mg Tablet XR:

Follow your doctor's instructions precisely regarding dosage and treatment length for Glura M 100mg/1000mg Extended-Release Tablets. Ingest the tablet whole; do not break, crush, or chew. Administer this medication with a meal.

How Glura M 100mg/1000mg Tablet XR works:

Glura M XR, a 100mg/1000mg tablet, combines sitagliptin and metformin to improve blood glucose management. Sitagliptin boosts insulin production by the pancreas, enhances insulin utilization, and diminishes hepatic glucose output. Metformin, a biguanide, reduces liver glucose production, slows intestinal glucose absorption, and increases insulin sensitivity. This dual action leads to superior glycemic control.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Concurrent use of alcohol and Glura M 100mg/1000mg XR tablets is inadvisable.

PregnancyPregnancyCONSULT YOUR DOCTOR

Extended-release Glura M 100mg/1000mg tablets may pose pregnancy risks. While human data is scarce, animal research indicates potential harm to a fetus. A physician will assess the advantages against possible dangers prior to prescribing. Seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Extended-release Glura M 100mg/1000mg tablets are likely unsafe for breastfeeding mothers. Available human data indicates potential transfer to breast milk, posing a risk to the infant.

DrivingDrivingCAUTION

Driving may be impaired by excessively low or high blood glucose levels. Refrain from driving if you experience these conditions.

KidneyKidneyCAUTION

Patients with impaired kidney function should use Glura M 100mg/1000mg XR tablets cautiously, potentially requiring dosage modification. Physician consultation is recommended. Glura M 100mg/1000mg XR tablets are contraindicated in individuals with severe kidney disease. Routine monitoring of renal function is advised during treatment.

LiverLiverUNSAFE

Extended-release Glura M 100mg/1000mg tablets are likely contraindicated for individuals with hepatic impairment and should be omitted. Medical advice is recommended.

What if you forget to take Glura M 100mg/1000mg Tablet XR :

Should you forget a Glura M 100mg/1000mg extended-release tablet, administer it immediately upon remembrance. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Glura M 100mg/1000mg Tablet XR

LabelValue
Developing Habits No.
Treatment Category Diabetes Management

FAQs on Glura M 100mg/1000mg Tablet XR

Glura M 100mg/1000mg XR tablets combine sitagliptin and metformin to treat type 2 diabetes in adults. This combination improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin increases insulin release by inhibiting DPP-4. This medication is not suitable for individuals under 18.
Prolonged use of Glura M 100mg/1000mg Tablet XR can lead to vitamin B12 deficiency by hindering its absorption in the stomach. This deficiency, if left untreated, may result in anemia, neurological issues such as tingling, numbness in extremities, weakness, urinary problems, cognitive changes, and ataxia. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Glura M 100mg/1000mg Tablet XR commonly causes hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory tract infections. Rare but serious side effects include lactic acidosis. Prolonged use may also result in vitamin B12 deficiency.
Glura M 100mg/1000mg Tablet XR is contraindicated in patients with allergies to its components or excipients, and those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Glura M 100mg/1000mg Tablet XR with alcohol is unsafe and may heighten the risk of lactic acidosis.
Store this medication in its original, tightly closed container, as directed on the label or packaging. Discard any unused medication and keep it out of reach of children, pets, and others.
Glura M 100mg/1000mg XR tablets can cause lactic acidosis (MALA, Metformin-associated lactic acidosis), a serious medical emergency resulting from excess blood lactic acid. This rare side effect necessitates caution in patients with kidney disease, the elderly, or those who consume excessive alcohol. Symptoms include muscle pain or weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If these occur, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Glura M 100mg/1000mg XR tablets combine sitagliptin and metformin to treat type 2 diabetes in adults. This combination improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin boosts insulin release by inhibiting DPP-4. This medication is not suitable for individuals under 18.
Glura M 100mg/1000mg Tablet XR commonly causes hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use may also result in vitamin B12 deficiency.
Glura M 100mg/1000mg Tablet XR is contraindicated in patients with allergies to its components or excipients, and those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Glura M 100mg/1000mg Tablet XR and alcohol is unsafe and may heighten the risk of lactic acidosis.
Glura M 100mg/1000mg XR tablets can cause lactic acidosis (MALA, or Metformin-associated lactic acidosis), a serious medical emergency resulting from excessive blood lactic acid. This rare side effect necessitates avoiding the drug in patients with kidney disease, the elderly, or heavy alcohol users. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If these occur, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Prolonged use of Glura M 100mg/1000mg Tablet XR can lead to vitamin B12 deficiency by hindering its absorption in the stomach. This deficiency may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, urinary issues, cognitive changes, and ataxia), if left unaddressed. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Store this medication in its original, tightly closed container, as directed on the label. Discard any unused medication and keep it out of reach of children, pets, and others.
Glura M 100mg/1000mg XR tablets combine sitagliptin and metformin to manage type 2 diabetes in adults. This combination improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin increases insulin release by inhibiting DPP-4. This medication is not suitable for individuals under 18.
Glura M 100mg/1000mg Tablet XR may cause common side effects such as hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infection. Rare but serious side effects include lactic acidosis. Prolonged use can also result in vitamin B12 deficiency.
Patients with known allergies to Glura M 100mg/1000mg Tablet XR components or excipients, or with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis, should not use this medication.
Combining Glura M 100mg/1000mg Tablet XR with alcohol is unsafe and may heighten the risk of lactic acidosis.
Glura M 100mg/1000mg XR (containing metformin) can cause lactic acidosis, a serious medical emergency involving high blood lactic acid levels (also known as MALA). This rare side effect necessitates avoiding metformin in patients with kidney disease, the elderly, or those who consume excessive alcohol. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If these occur, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Prolonged use of Glura M 100mg/1000mg Tablet XR can lead to vitamin B12 deficiency by hindering its absorption. This deficiency, if left untreated, may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, and balance problems), urinary issues, and cognitive changes. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Store this medication in its original, tightly closed container, following the storage instructions on the packaging. Discard any unused medication and keep it out of reach of children, pets, and others.
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