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Glura M 50mg/500mg Tablet XR

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Prescription Required

Marketer

Comed Chemicals Ltd

Salt Composition

Sitagliptin (50mg) + Metformin (500mg)

Overview Glura M 50mg/500mg Tablet XR

Diabex Duo 50mg/500mg Extended-Release Tablets combine two medications to manage elevated blood glucose in patients with type 2 diabetes. This dual action helps prevent serious diabetic complications like renal impairment and vision loss, and may lessen the risk of cardiovascular events. Diabex Duo may be used as monotherapy or in conjunction with other antidiabetic agents. Optimal results are achieved with a balanced diet and regular physical activity. Dosage is individualized based on your health status, glucose levels, and other medications. Taking it with food minimizes gastrointestinal distress. Consistent daily dosing at the same time maximizes efficacy; discontinuation should only occur under your physician's guidance. Adherence to your prescribed diet and exercise regimen is crucial for diabetes control. Common side effects include diarrhea, nausea, vomiting, stomach upset, headache, and pharyngitis. Hypoglycemia is a potential side effect, especially when combined with insulin or sulfonylureas; learn to recognize and manage this complication. This medication isn't appropriate for all individuals. Inform your doctor of any pre-existing kidney, liver, or heart conditions, pancreatic issues, or excessive alcohol consumption before starting. Pregnant or lactating women should seek medical advice prior to use. Drug interactions are possible; disclose all medications to ensure treatment safety. Alcohol consumption should be limited due to its hypoglycemic effects. Your doctor will monitor your renal function and blood sugar levels throughout treatment.

Primary Ingredients of Glura M 50mg/500mg Tablet XR

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Uses of Glura M 50mg/500mg Tablet XR

Managing type 2 diabetes

Major Benefits of Glura M 50mg/500mg Tablet XR:

Follow your doctor's instructions precisely regarding dosage and treatment length for Glura M 50mg/500mg Extended-Release Tablets. Ingest the tablet whole; do not crush, chew, or divide it. Administer this medication with a meal.

Common Side effects of Glura M 50mg/500mg Tablet XR:

  • Decreased appetite
  • Vomiting
  • Upper respiratory tract infection
  • Hypoglycemia (low blood glucose level)
  • Abdominal bloating
  • Nausea
  • Diarrhea

How to use Glura M 50mg/500mg Tablet XR:

Follow your doctor's instructions precisely regarding the dosage and treatment length for this medication. Ingest the Glura M 50mg/500mg Extended-Release tablet whole; do not chew, crush, or divide it. Administer this medication with a meal.

How Glura M 50mg/500mg Tablet XR works:

Glura M 50mg/500mg Extended-Release tablets combine sitagliptin and metformin to manage blood glucose. Sitagliptin enhances insulin production by the pancreas, improves insulin utilization, and decreases hepatic glucose output. Metformin, a biguanide, reduces liver glucose production, slows intestinal glucose absorption, and increases insulin sensitivity. This dual action leads to improved glycemic control.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Combining Glura M 50mg/500mg extended-release tablets with alcohol is dangerous.

PregnancyPregnancyCONSULT YOUR DOCTOR

Extended-release Glura M 50mg/500mg tablets might pose pregnancy risks. While human data is scarce, animal research indicates potential harm to a fetus. A physician will assess the advantages against possible dangers prior to prescribing. Seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Extended-release Glura M 50mg/500mg tablets are likely not safe for use while breastfeeding. Available human data indicates potential transfer to breast milk, posing a risk to the infant.

DrivingDrivingCAUTION

Driving ability can be impaired by both hypoglycemia and hyperglycemia. Refrain from driving if you experience these conditions.

KidneyKidneyCAUTION

Patients with kidney impairment should exercise caution when using Glura M 50mg/500mg XR tablets; dosage modification may be necessary. Consult your physician for guidance. Glura M 50mg/500mg XR tablets are contraindicated in individuals with severe kidney disease. Routine monitoring of renal function is recommended during treatment.

LiverLiverUNSAFE

Extended-release Glura M 50mg/500mg tablets are contraindicated for individuals with hepatic impairment and should be avoided. Medical advice is recommended.

What if you forget to take Glura M 50mg/500mg Tablet XR :

Should you forget to take a Glura M 50mg/500mg extended-release tablet, administer it immediately upon remembrance. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Glura M 50mg/500mg Tablet XR

LabelValue
Developing Habits No.
Treatment Category Diabetes Management

FAQs on Glura M 50mg/500mg Tablet XR

Glura M 50mg/500mg XR tablets combine sitagliptin and metformin to manage type 2 diabetes in adults. This combination improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin boosts insulin release by inhibiting DPP-4. This medication is not suitable for individuals under 18.
Prolonged use of Glura M 50mg/500mg Tablet XR can lead to vitamin B12 deficiency by hindering its absorption. This deficiency, if left untreated, may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, and balance problems), urinary issues, and cognitive changes. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Glura M 50mg/500mg XR tablets may cause common side effects such as low blood sugar (hypoglycemia), altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use may also result in vitamin B12 deficiency.
Glura M 50mg/500mg Tablet XR is contraindicated in patients with allergies to its components or excipients, and those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Glura M 50mg/500mg Tablet XR with alcohol is unsafe and may heighten the risk of lactic acidosis.
Store this medication in its original, tightly closed container, as directed on the label or packaging. Dispose of any unused medication properly and ensure it's inaccessible to children, pets, and others.
Glura M 50mg/500mg XR (containing metformin) can cause lactic acidosis (MALA), a serious medical emergency involving high blood lactic acid levels. This rare side effect necessitates avoiding metformin in patients with kidney disease, the elderly, or those who consume excessive alcohol. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If experienced, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Glura M 50mg/500mg XR tablets combine sitagliptin and metformin to manage type 2 diabetes in adults. This combination improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin boosts insulin release by inhibiting DPP-4. This medication is not suitable for individuals under 18.
Glura M 50mg/500mg Tablet XR may cause common side effects such as low blood sugar (hypoglycemia), altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use may also result in vitamin B12 deficiency.
Glura M 50mg/500mg Tablet XR is contraindicated in patients with known allergies to its components or excipients, and in those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Glura M 50mg/500mg Tablet XR with alcohol is unsafe and may heighten the risk of lactic acidosis.
Glura M 50mg/500mg XR can cause lactic acidosis (MALA, Metformin-associated lactic acidosis), a serious medical emergency resulting from excessive blood lactic acid. This rare side effect necessitates caution in patients with kidney disease, the elderly, or those consuming significant alcohol. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If these occur, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Prolonged use of Glura M 50mg/500mg Tablet XR can lead to vitamin B12 deficiency by hindering its absorption. This deficiency may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, and balance issues), urinary problems, and cognitive changes. To mitigate these risks, annual supplemental vitamin B12 is recommended by some researchers.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication; keep it out of reach of children, pets, and others.
Glura M 50mg/500mg XR tablets combine sitagliptin and metformin to manage type 2 diabetes in adults. This combination improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin boosts insulin release by inhibiting DPP-4. This medication is not suitable for individuals under 18.
Glura M 50mg/500mg Tablet XR may cause common side effects such as low blood sugar (hypoglycemia), altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use can also result in vitamin B12 deficiency.
Glura M 50mg/500mg Tablet XR is contraindicated in patients with known allergies to its components or excipients, and those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Glura M 50mg/500mg Tablet XR with alcohol is unsafe and may heighten the risk of lactic acidosis.
Glura M 50mg/500mg XR (containing metformin) can cause lactic acidosis (MALA), a serious medical emergency resulting from excessive blood lactic acid. This rare side effect necessitates caution in patients with kidney disease, the elderly, or those who consume significant alcohol. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea/vomiting, abdominal pain, and bradycardia. If these occur, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Prolonged use of Glura M 50mg/500mg Tablet XR can lead to vitamin B12 deficiency by hindering its absorption in the stomach. This deficiency may cause anemia, nerve damage (manifested as tingling, numbness in extremities, weakness, and balance problems), and urinary issues, potentially impacting mental status. To mitigate these risks, supplemental vitamin B12 is recommended annually by some researchers.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication and keep it out of reach of children, pets, and others.
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