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Glura M XR 100/500 Tablet

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Prescription Required

Marketer

Eris Lifesciences Ltd

Salt Composition

Sitagliptin (100mg) + Metformin (500mg)

Overview Glura M XR 100/500 Tablet

Metformin/glimepiride extended-release tablets (100/500 mg) manage elevated blood glucose in type 2 diabetes patients. This dual-action medication mitigates severe diabetic complications like renal impairment and vision loss, potentially lowering cardiovascular event risk. It can be used independently or in conjunction with other antidiabetic therapies. Optimal results require adherence to a balanced diet and regular physical activity. Dosage is individualized based on your health status, glucose readings, and existing medications. Consuming it with food minimizes gastrointestinal discomfort. Consistent daily dosing at the same time maximizes effectiveness; discontinuation should only occur under medical supervision. Maintaining the prescribed diet and exercise plan is crucial for diabetes control, as lifestyle significantly impacts management. Common adverse effects include diarrhea, nausea, vomiting, dyspepsia, headache, and pharyngitis. Hypoglycemia, a potential side effect when combined with insulin or sulfonylureas, necessitates awareness of its symptoms and management. This medication isn't universally suitable. Prior to commencement, inform your physician of any history of renal, hepatic, or cardiac disease, pancreatic issues, or significant alcohol consumption. Pregnant or lactating individuals require medical consultation. Drug interactions are possible; disclose all medications to ensure safety. Alcohol consumption should be minimized due to its hypoglycemic effect. Your doctor will monitor renal function and glucose levels throughout treatment.

Primary Ingredients of Glura M XR 100/500 Tablet

No text provided to rephrase.

Uses of Glura M XR 100/500 Tablet

Managing Type 2 diabetes

Major Benefits of Glura M XR 100/500 Tablet:

Follow your doctor's instructions or consult the product label for guidance. Take Glura M XR 100/500 Tablets with food.

Common Side effects of Glura M XR 100/500 Tablet:

  • Decreased appetite
  • Vomiting
  • Upper respiratory tract infection
  • Hypoglycemia (low blood glucose level)
  • Abdominal bloating
  • Nausea
  • Diarrhea

How to use Glura M XR 100/500 Tablet:

Follow your physician's instructions or consult the product label for guidance. Always take Glura M XR 100/500 Tablets with a meal.

How Glura M XR 100/500 Tablet works:

Glura M XR 100/500 tablets combine sitagliptin and metformin to manage blood sugar. Sitagliptin enhances insulin production by the pancreas, improves the body's insulin utilization, and decreases hepatic glucose output. Metformin, a biguanide, reduces liver glucose production, slows intestinal glucose absorption, and increases insulin sensitivity. This dual action leads to improved glycemic control.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Combining Glura M XR 100/500 Tablet with alcohol is inadvisable due to safety concerns.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Glura M XR 100/500 Tablet during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to the fetus. A physician will assess the advantages against possible risks prior to prescription. Physician consultation is advised.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

The use of Glura M XR 100/500 Tablet while breastfeeding is likely inadvisable. Available human data indicates a potential for the medication to transfer to breast milk, posing a risk to the infant.

DrivingDrivingCAUTION

Driving ability can be impaired by both hypoglycemia and hyperglycemia. Refrain from driving if you experience these conditions.

KidneyKidneyCAUTION

Patients with kidney impairment should use Glura M XR 100/500 Tablets cautiously, potentially requiring dosage modification. Physician consultation is recommended. The medication is contraindicated in individuals with severe kidney disease. Routine monitoring of renal function is advised during treatment.

LiverLiverUNSAFE

Patients with liver conditions should likely refrain from using Glura M XR 100/500 Tablets due to potential safety concerns. A physician's consultation is recommended.

What if you forget to take Glura M XR 100/500 Tablet :

Should you forget a Glura M XR 100/500 Tablet dose, administer it promptly. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual medication regimen. Avoid taking a double dose.

Facts to Know About Glura M XR 100/500 Tablet

LabelValue
Developing Habits No.
Treatment Category Diabetes Management

FAQs on Glura M XR 100/500 Tablet

Glura M XR 100/500 Tablet combines sitagliptin and metformin to manage type 2 diabetes in adults. This medication improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin boosts insulin release by inhibiting DPP-4. It's not suitable for individuals under 18.
Prolonged Glura M XR 100/500 Tablet use can lead to vitamin B12 deficiency by hindering its absorption. This deficiency may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, urinary issues, cognitive changes, and ataxia), if left unaddressed. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Glura M XR 100/500 Tablet may cause common side effects such as hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infection. Rare but serious side effects include lactic acidosis. Prolonged use may also result in vitamin B12 deficiency.
Patients with known allergies to Glura M XR 100/500 Tablet components or excipients, or those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis should not use this medication.
Combining Glura M XR 100/500 tablets with alcohol is unsafe and may raise the risk of lactic acidosis.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication and keep it out of reach of children, pets, and others.
Glura M XR 100/500 Tablet can cause lactic acidosis (MALA, or Metformin-associated lactic acidosis), a serious medical emergency resulting from excessive blood lactic acid. This rare side effect necessitates avoiding the medication in patients with kidney disease, the elderly, or those who consume significant alcohol. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If you experience these, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Glura M XR 100/500 tablets combine sitagliptin and metformin to manage type 2 diabetes in adults. This combination improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin boosts insulin release by inhibiting DPP-4. This medication is not suitable for individuals under 18.
Glura M XR 100/500 Tablet may cause common side effects such as hypoglycemia, taste changes, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use can also result in vitamin B12 deficiency.
Patients with known allergies to Glura M XR 100/500 Tablet components or excipients, or those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis, should not use this medication.
Combining Glura M XR 100/500 Tablet with alcohol is unsafe and may heighten the risk of lactic acidosis.
Glura M XR 100/500 Tablets can cause lactic acidosis (MALA), a serious medical emergency characterized by excessive blood lactic acid. This rare side effect, more likely in patients with kidney disease, older adults, or those who consume excessive alcohol, necessitates avoidance in such individuals. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. Should these symptoms occur, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Prolonged Glura M XR 100/500 Tablet use can lead to vitamin B12 deficiency by hindering its absorption. This deficiency, if left unaddressed, may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, urinary issues, cognitive changes, and ataxia), and requires supplemental vitamin B12, possibly annually, to mitigate these risks.
Store this medication in its original, tightly closed container, following the storage instructions on the packaging. Discard any unused medication and ensure it's inaccessible to children, pets, and others.
Glura M XR 100/500 Tablet combines sitagliptin and metformin to manage type 2 diabetes in adults. This combination improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin boosts insulin release by inhibiting DPP-4. It's not suitable for individuals under 18.
Glura M XR 100/500 Tablet may cause common side effects such as hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infection. Rare but serious side effects include lactic acidosis. Prolonged use may result in vitamin B12 deficiency.
Glura M XR 100/500 Tablets are contraindicated in patients with allergies to any ingredient or excipient. Avoid use in patients with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Glura M XR 100/500 tablets with alcohol is unsafe and may heighten the risk of lactic acidosis.
Glura M XR 100/500 Tablets can cause lactic acidosis, a serious medical emergency characterized by excessive blood lactic acid (also known as MALA—Metformin-associated lactic acidosis). This rare side effect is more likely in patients with kidney disease, the elderly, or those who consume significant alcohol. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If you experience these, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Prolonged Glura M XR 100/500 Tablet use can lead to vitamin B12 deficiency by hindering its absorption. This deficiency may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, and urinary issues), and cognitive changes (including balance problems). To mitigate these risks, supplemental vitamin B12 is recommended annually by some researchers.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication and ensure it's kept out of reach of children, pets, and others.
Glura M XR 100/500 Tablet
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