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Glura M XR 500 Tablet

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Prescription Required

Marketer

Eris Lifesciences Ltd

Salt Composition

Sitagliptin (50mg) + Metformin (500mg)

Overview Glura M XR 500 Tablet

Metformin/Glimepiride extended-release 500mg tablets manage elevated blood glucose in type 2 diabetes patients by combining two active ingredients. This dual action helps prevent serious diabetic complications like vision loss and kidney disease, potentially lessening heart attack and stroke risk. This medication may be prescribed independently or alongside other antidiabetic therapies, and its efficacy is enhanced by a balanced diet and consistent exercise. Dosage is individualized based on your health status, blood glucose readings, and other concurrent medications. Consuming it with meals minimizes gastrointestinal discomfort. Consistent daily dosing at the same time maximizes therapeutic benefit; discontinuation should only occur under physician guidance. Adherence to the prescribed diet and exercise plan is crucial for optimal diabetes control, as lifestyle significantly impacts blood sugar management. Common side effects include nausea, vomiting, diarrhea, stomach upset, headache, and pharyngitis. Hypoglycemia, a potential side effect when used with insulin or sulfonylureas, requires understanding of its symptoms and management. This medication is not universally suitable. Prior to commencing treatment, inform your physician of any pre-existing kidney, liver, or heart conditions, pancreatic issues, or significant alcohol consumption. Pregnant or lactating individuals should seek medical counsel before use. Interactions with other medications are possible; disclose all current medications to your doctor to ensure safety. Alcohol consumption should be limited due to its hypoglycemic effect. Your doctor will monitor kidney function and blood glucose levels throughout treatment.

Uses of Glura M XR 500 Tablet

Managing type 2 diabetes

Major Benefits of Glura M XR 500 Tablet:

Follow your doctor's instructions or refer to the product labeling for administration guidelines. Ingest Glura M XR 500 Tablet with a meal.

Common Side effects of Glura M XR 500 Tablet:

  • Decreased appetite
  • Vomiting
  • Upper respiratory tract infection
  • Hypoglycemia (low blood glucose level)
  • Abdominal bloating
  • Nausea
  • Diarrhea

How to use Glura M XR 500 Tablet:

Follow your physician's instructions or consult the product label for proper administration. Glura M XR 500 Tablets should be ingested with a meal.

How Glura M XR 500 Tablet works:

Glura M XR 500 Tablet merges sitagliptin and metformin to enhance blood sugar management. Sitagliptin boosts insulin production by the pancreas, improves insulin utilization, and diminishes hepatic glucose output. Metformin, a biguanide, reduces liver glucose production, slows intestinal glucose absorption, and increases insulin sensitivity. This combined action leads to superior glycemic control.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Combining Glura M XR 500 Tablets with alcohol is strongly discouraged due to safety concerns.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Glura M XR 500 Tablet during pregnancy may pose risks. While human research is scarce, animal studies indicate potential harm to a developing fetus. A physician will assess the potential advantages against the risks prior to prescribing. Physician consultation is advised.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Extended-release Glura M 500 mg tablets are likely unsuitable for breastfeeding mothers. Available human data indicate potential transfer of the medication into breast milk, posing a risk to the infant.

DrivingDrivingCAUTION

Driving ability can be impaired by both hypoglycemia and hyperglycemia. Refrain from driving if you experience these conditions.

KidneyKidneyCAUTION

Patients with impaired kidney function should use Glura M XR 500mg tablets cautiously, potentially requiring dosage modification. Severe kidney disease contraindicates the use of Glura M XR 500mg tablets. Regular kidney function monitoring is recommended during treatment. Physician consultation is advised.

LiverLiverUNSAFE

Patients with liver impairment should not take Glura M XR 500 Tablets; use is strongly discouraged. Medical advice is recommended.

What if you forget to take Glura M XR 500 Tablet :

Should you forget a Glura M XR 500 Tablet dose, administer it promptly. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Glura M XR 500 Tablet

LabelValue
Developing Habits No.
Type of Therapy Diabetes Management

FAQs on Glura M XR 500 Tablet

Glura M XR 500 Tablet combines sitagliptin and metformin to manage type 2 diabetes in adults. It enhances blood glucose control when used with diet and exercise. Metformin reduces liver glucose production and improves insulin sensitivity, while sitagliptin boosts insulin release by inhibiting DPP-4. This medication is not suitable for individuals under 18.
Prolonged Glura M XR 500 Tablet use can lead to vitamin B12 deficiency by hindering its absorption. This deficiency may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, urinary issues, cognitive changes, and balance problems), if left unaddressed. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Glura M XR 500 Tablet may cause common side effects such as low blood sugar (hypoglycemia), altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use can also result in vitamin B12 deficiency.
Patients allergic to Glura M XR 500 Tablet components or excipients should not use it. It should also be avoided by those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Glura M XR 500 tablets with alcohol is unsafe and may heighten the risk of lactic acidosis.
Store this medication in its original, tightly closed container, as directed on the label. Discard any unused medication and ensure it's inaccessible to children, pets, and others.
Glura M XR 500 Tablet (containing metformin) can cause lactic acidosis, a serious medical emergency resulting from excess blood lactic acid (also known as MALA). This rare side effect necessitates avoidance in patients with kidney disease, the elderly, or those consuming significant alcohol. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea/vomiting, abdominal pain, and bradycardia. If experienced, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Glura M XR 500 Tablet combines sitagliptin and metformin to manage type 2 diabetes in adults. This combination improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin boosts insulin release by inhibiting DPP-4. It's not suitable for individuals under 18.
Glura M XR 500 Tablet may cause common side effects such as hypoglycemia (low blood sugar), altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use may also result in vitamin B12 deficiency.
Glura M XR 500 Tablet is contraindicated in patients with allergies to its components or excipients, and in those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Glura M XR 500 Tablets with alcohol is unsafe and may heighten the risk of lactic acidosis.
Glura M XR 500 Tablet (containing metformin) can cause lactic acidosis, a serious medical emergency characterized by excessive blood lactic acid (also known as MALA – Metformin-Associated Lactic Acidosis). This rare side effect necessitates caution in patients with kidney disease, older adults, and heavy alcohol users. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If experienced, discontinue Sitagliptin + Metformin immediately and seek medical attention.
Prolonged use of Glura M XR 500 Tablets can lead to vitamin B12 deficiency by hindering its absorption in the stomach. This deficiency, if left untreated, may result in anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, and balance problems), urinary issues, and cognitive changes. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication and keep it out of reach of children, pets, and others.
Glura M XR 500 Tablet combines sitagliptin and metformin to treat type 2 diabetes mellitus in adults. This combination improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin boosts insulin release by inhibiting DPP-4. It's not suitable for individuals under 18.
Glura M XR 500 Tablet may cause common side effects such as hypoglycemia, taste changes, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects, including lactic acidosis, are also possible. Prolonged use may result in vitamin B12 deficiency.
Glura M XR 500 Tablets are contraindicated in patients with allergies to any ingredient or excipient. Avoid use in patients with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Glura M XR 500 tablets with alcohol is unsafe and may heighten the risk of lactic acidosis.
Glura M XR 500 Tablet (containing metformin) can cause lactic acidosis, a serious medical emergency characterized by high blood lactic acid levels (also known as MALA – Metformin-associated lactic acidosis). This rare side effect necessitates avoiding metformin in patients with kidney disease, the elderly, or those who consume excessive alcohol. Symptoms include muscle pain or weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If you experience these, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Prolonged Glura M XR 500 Tablet use can lead to vitamin B12 deficiency by impairing its absorption. This deficiency, if left untreated, may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, and balance problems), urinary issues, and cognitive changes. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication and ensure it remains inaccessible to children, pets, and others.
Glura M XR 500 Tablet
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