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Glybest M 80mg/500mg Tablet

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Boon & Bastion Formulations

Salt Composition

Gliclazide (80mg) + Metformin (500mg)

Overview Glybest M 80mg/500mg Tablet

Metformin/Glibenclamide 80mg/500mg tablets are classified as antidiabetic medications. This dual-drug formulation manages type 2 diabetes in adults by regulating blood glucose. Administer this medication with food, consistently at the same time daily for optimal efficacy. Dosage is determined by your physician and may be adjusted based on blood sugar monitoring. Continuous use is crucial; discontinuation without medical guidance can elevate blood sugar, potentially leading to kidney complications, vision impairment, neuropathy, and limb loss. This medication complements a comprehensive diabetes management plan including diet, exercise, and weight management as directed by your doctor. Lifestyle choices are integral to diabetes control. Common side effects include hypoglycemia (low blood sugar), characterized by sweating, dizziness, headache, and tremors; constipation, and vomiting. Learn to recognize and treat hypoglycemia; maintain regular meals and carry a rapid-acting glucose source (e.g., sugary snacks or juice). Alcohol consumption increases hypoglycemia risk and should be limited. Additional potential side effects encompass altered taste, nausea, diarrhea, abdominal discomfort, headache, and upper respiratory infections. Weight gain may occur. This medication is contraindicated for type 1 diabetes, diabetic ketoacidosis, and severe hepatic or renal impairment. Individuals with a history of heart disease should inform their physician before commencing treatment. Its suitability for pregnant or breastfeeding women requires prior medical consultation. Regular blood glucose monitoring is necessary, along with potential blood tests to assess blood cell counts and liver function.

Uses of Glybest M 80mg/500mg Tablet

Adult-onset diabetes

Major Benefits of Glybest M 80mg/500mg Tablet:

Consume this medication precisely as your physician directs, adhering to both the prescribed dosage and treatment length. Ingest the Glybest M 80mg/500mg Tablet whole; avoid chewing, crushing, or fracturing it. Administer this medication with a meal.

Common Side effects of Glybest M 80mg/500mg Tablet:

  • Hypoglycemia (low blood glucose level)
  • Headache
  • Dizziness
  • Diarrhea
  • Upper respiratory tract infection
  • Nausea
  • Flatulence
  • Constipation

How to use Glybest M 80mg/500mg Tablet:

Follow your doctor's instructions precisely regarding dosage and treatment length for this medication. Ingest the Glybest M 80mg/500mg tablet whole; do not break, crush, or chew it. Administer this medication with a meal.

How Glybest M 80mg/500mg Tablet works:

Each Glybest M 80mg/500mg tablet combines the antidiabetic agents gliclazide and metformin.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Combining Glybest M 80mg/500mg Tablet and alcohol is not advisable due to safety concerns.

PregnancyPregnancyCONSULT YOUR DOCTOR

Using Glybest M 80mg/500mg tablets during pregnancy is contraindicated due to established risks to the fetus. A physician might exceptionally prescribe it in critical circumstances where the potential benefits outweigh the known hazards. Always seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Use of Glybest M 80mg/500mg tablets while breastfeeding is likely inadvisable. Insufficient human data indicates potential drug transfer to breast milk, posing a possible risk to the infant.

DrivingDrivingCAUTION

Driving ability can be impaired by both hypoglycemia and hyperglycemia. Refrain from driving if you experience these conditions.

KidneyKidneyCAUTION

Patients with kidney impairment should use Glybest M 80mg/500mg tablets cautiously, potentially requiring dosage modification. Severe kidney disease contraindicates Glybest M 80mg/500mg tablet use. Physician consultation is essential. Routine kidney function monitoring is recommended during treatment.

LiverLiverCAUTION

Individuals with liver impairment should use Glybest M 80mg/500mg tablets cautiously. Dosage modifications may be necessary for these patients. Physician consultation is advised. In those with mild to moderate liver disease, Glybest M 80mg/500mg tablets are typically initiated at a low dosage; however, their use is contraindicated in patients with severe hepatic dysfunction.

What if you forget to take Glybest M 80mg/500mg Tablet :

Should you forget a Glybest M 80mg/500mg Tablet dose, administer it promptly. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Glybest M 80mg/500mg Tablet

LabelValue
Potential for Dependence None.
Type of Medication Medication for diabetes

FAQs on Glybest M 80mg/500mg Tablet

Glybest M 80mg/500mg tablets contain gliclazide and metformin, working synergistically to manage type 2 diabetes mellitus in adults. This medication enhances glycemic control when combined with a suitable diet and exercise regimen. Gliclazide stimulates pancreatic insulin secretion, while metformin reduces hepatic glucose production and increases insulin responsiveness. This dual-agent therapy is unsuitable for type 1 diabetes management.
Glybest M 80mg/500mg tablets may cause common adverse reactions such as low blood sugar (hypoglycemia), taste disturbances, nausea, abdominal pain, diarrhea, headache, and upper respiratory infections. Rare but potentially severe side effects, including lactic acidosis, are also possible. Prolonged use may result in vitamin B12 deficiency.
Glybest M 80mg/500mg Tablets can induce hypoglycemia, characterized by low blood sugar. Manifestations of low blood sugar include nausea, headache, irritability, hunger pangs, sweating, dizziness, tachycardia, and feelings of anxiety or tremors. The risk increases with skipped or delayed meals, alcohol consumption, excessive physical activity, or concomitant use of other antidiabetic medications. Consequently, consistent blood glucose monitoring is crucial. Carrying readily available glucose sources, such as glucose tablets, honey, or fruit juice, is recommended.
Glybest M 80mg/500mg Tablets can cause lactic acidosis, a serious medical condition characterized by excessive blood lactic acid. Also termed Metformin-associated lactic acidosis (MALA), this is an infrequent complication of metformin use. To prevent it, the medication should be avoided in individuals with kidney impairment, the elderly, and heavy alcohol consumers. Lactic acidosis symptoms might present as muscle aches or weakness, vertigo, fatigue, cold extremities, respiratory distress, nausea, vomiting, abdominal pain, or bradycardia. Should these symptoms appear, discontinue Glybest M 80mg/500mg Tablets and seek immediate medical attention.
Indeed, prolonged Glybest M 80mg/500mg Tablet ingestion can lead to vitamin B12 insufficiency. This is because the medication impedes the stomach's absorption of vitamin B12. Left unaddressed, this deficiency might result in anemia, neurological complications, such as paresthesia in the extremities, generalized weakness, urinary dysfunction, cognitive impairment, and gait instability. To mitigate these risks, supplemental vitamin B12 is recommended annually by some experts.
Glybest M 80mg/500mg Tablets are contraindicated in individuals with hypersensitivity to any constituent or inactive ingredient. Their use should also be avoided in patients exhibiting moderate to severe renal impairment or those with pre-existing metabolic acidosis, such as diabetic ketoacidosis.
Combining Glybest M 80mg/500mg tablets and alcohol is unsafe. This combination can reduce blood sugar to dangerously low levels (hypoglycemia) and heighten the risk of lactic acidosis.
Glybest M 80mg/500mg tablets contain gliclazide and metformin, working synergistically to manage type 2 diabetes mellitus in adults. This dual-action therapy enhances glycemic control when coupled with a healthy diet and exercise regimen. Gliclazide stimulates pancreatic insulin secretion, while metformin reduces hepatic glucose output and increases insulin sensitivity. This medication is unsuitable for managing type 1 diabetes.
Glybest M 80mg/500mg tablets may cause frequent side effects such as low blood sugar (hypoglycemia), taste disturbances, nausea, abdominal pain, loose stools, headache, and upper respiratory infections. Rare but potentially severe adverse reactions, including lactic acidosis, are also possible. Prolonged treatment may result in vitamin B12 deficiency.
Glybest M 80mg/500mg Tablets can induce hypoglycemia (low blood sugar). Low blood sugar may manifest as nausea, headache, irritability, hunger, sweating, dizziness, tachycardia, and anxiety or tremors. The risk increases with missed or delayed meals, alcohol consumption, excessive physical activity, or concomitant use of other antidiabetic medications. Therefore, consistent blood glucose monitoring is crucial. Always carry readily available glucose sources, such as glucose tablets, honey, or fruit juice.
Glybest M 80mg/500mg Tablets may cause lactic acidosis, a serious medical condition characterized by excessive blood lactic acid. Also termed Metformin-associated lactic acidosis (MALA), this is an uncommon adverse reaction to metformin. Risk factors include pre-existing kidney disease, advanced age, and significant alcohol consumption. Symptoms can manifest as muscle aches or weakness, lightheadedness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, or bradycardia. Should these symptoms appear, discontinue Glybest M 80mg/500mg Tablet use and seek immediate medical attention.
Indeed, prolonged consumption of Glybest M 80mg/500mg Tablets can lead to a vitamin B12 deficit. This deficiency arises from the medication's interference with vitamin B12 absorption in the gastrointestinal tract. Left unaddressed, this can result in anemia, neurological complications, including paresthesia in the extremities, generalized weakness, urinary dysfunction, cognitive impairment, and gait instability. To mitigate these risks, supplemental vitamin B12 intake, at least annually, has been proposed by some investigators.
Patients with a history of hypersensitivity to Glybest M 80mg/500mg Tablet components or inactive ingredients should not use this medication. Its administration is also contraindicated in individuals with moderate to severe renal impairment or pre-existing metabolic acidosis, such as diabetic ketoacidosis.
Consuming alcohol while taking Glybest M 80mg/500mg tablets is unsafe. This combination may cause dangerously low blood sugar and heighten the risk of lactic acidosis.
Glybest M 80mg/500mg Tabl...
37
MRP 45
17% off