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Glybir Plus G2 Tablet SR

Prescription Icon
Prescription Required

Marketer

Brilliant Lifesciences Pvt Ltd

Salt Composition

Glimepiride (2mg) + Metformin (500mg)

Overview Glybir Plus G2 Tablet SR

Combiflor G2 extended-release tablets are antidiabetic medications combining two agents for adult type 2 diabetes management. They help regulate blood glucose. Take these tablets with meals, consistently at the same time daily for optimal effect. Dosage is determined and adjusted by your physician based on your blood glucose response. Continuous use is crucial; abrupt cessation, without medical consultation, risks elevated blood sugar, potentially leading to kidney complications, vision impairment, neuropathy, and limb loss. This medication is one component of a comprehensive diabetes management plan, incorporating a healthy diet, regular physical activity, and weight management as directed by your doctor. Lifestyle significantly impacts diabetes control. Hypoglycemia (low blood sugar) is a frequent side effect; learn its symptoms (sweating, dizziness, headache, tremors) and appropriate management. Maintain regular mealtimes and carry a rapid-acting glucose source (sugary foods or juice). Alcohol consumption elevates hypoglycemia risk and should be avoided. Other potential side effects include altered taste, nausea, diarrhea, abdominal discomfort, headache, and upper respiratory infections. Weight gain may occur. This medication is contraindicated in type 1 diabetes, diabetic ketoacidosis, or severe liver/kidney disease. Disclose any history of heart disease to your doctor before starting treatment. Its suitability for pregnant or breastfeeding individuals requires medical consultation. Regular blood glucose monitoring is essential, along with potential blood tests to track blood cell counts and liver function.

Primary Ingredients of Glybir Plus G2 Tablet SR

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Uses of Glybir Plus G2 Tablet SR

Managing Type 2 diabetes

Major Benefits of Glybir Plus G2 Tablet SR:

Consume this medication precisely as your physician directs, adhering to both the prescribed dosage and timeframe. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Glybir Plus G2 Tablet SR should be administered with a meal.

Common Side effects of Glybir Plus G2 Tablet SR:

  • Headache
  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Diarrhea

How to use Glybir Plus G2 Tablet SR:

Follow your doctor's instructions precisely regarding dosage and treatment length for Glybir Plus G2 Tablet SR. Ingest the tablet whole; avoid chewing, crushing, or breaking it. Administer this medication with food.

How Glybir Plus G2 Tablet SR works:

Glybir Plus G2 Tablet SR combines glimepiride and metformin, two antidiabetic agents. Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin, thus reducing blood sugar. Metformin, a biguanide, acts by decreasing liver glucose production, slowing intestinal glucose absorption, and enhancing insulin sensitivity.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Combining Glybir Plus G2 Tablet SR and alcohol is not recommended due to safety concerns.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Glybir Plus G2 Tablet SR during pregnancy may pose risks. While human research is scarce, animal studies indicate potential harm to the fetus. A physician will assess the potential benefits against any risks prior to prescribing. Physician consultation is advised.

Breast feedingBreast feedingUNSAFE

Glybir Plus G2 sustained-release tablets are contraindicated for breastfeeding mothers. Evidence indicates potential infant harm from this medication.

DrivingDrivingCAUTION

Driving may be impaired by excessively low or high blood glucose levels. Refrain from driving if such symptoms arise.

KidneyKidneyCAUTION

Patients with kidney impairment should exercise caution when using Glybir Plus G2 Tablet SR; dosage modification may be necessary. Severe kidney disease contraindicates its use. Consult your physician. Kidney function should be regularly monitored during treatment.

LiverLiverCAUTION

Patients with liver impairment should use Glybir Plus G2 Tablet SR cautiously, potentially requiring dosage modification. Consult a physician. For individuals with mild to moderate liver disease, initiation at a low dose is typical; however, it's contraindicated in those with severe hepatic dysfunction.

What if you forget to take Glybir Plus G2 Tablet SR :

Should you forget a Glybir Plus G2 Tablet SR dose, take it immediately. If, however, your next dose is nearly due, omit the missed dose and resume your usual medication schedule. Never take a double dose.

Facts to Know About Glybir Plus G2 Tablet SR

LabelValue
Potential for Dependence None.
Medication Classification Medication for diabetes

FAQs on Glybir Plus G2 Tablet SR

Store this medication in its original, tightly sealed container or packaging. Follow the storage instructions provided on the label or packaging. Discard any remaining medication. Prevent access by children, pets, and others.
Glybir Plus G2 Tablet SR use carries a risk of lactic acidosis, a serious medical condition resulting from excessive blood lactic acid. Also termed MALA (Metformin-associated lactic acidosis), this rare but potentially harmful side effect is more likely in individuals with kidney impairment, the elderly, or those consuming significant alcohol. Symptoms can include muscle aches or weakness, vertigo, fatigue, cold extremities, dyspnea, nausea, emesis, abdominal discomfort, and bradycardia. If such symptoms appear, discontinue Glybir Plus G2 Tablet SR and seek immediate medical attention.
Glybir Plus G2 SR tablets contain glimepiride and metformin, two medications used together to manage type 2 diabetes mellitus in adults. This treatment improves blood sugar control when combined with a healthy diet and regular physical activity. Glimepiride stimulates insulin release from the pancreas to reduce blood glucose, while metformin reduces liver glucose production and enhances insulin effectiveness. This formulation is unsuitable for treating type 1 diabetes.
Glybir Plus G2 Tablet SR may cause common adverse reactions including low blood sugar (hypoglycemia), taste disturbances, nausea, abdominal pain, diarrhea, and headache. Rare but potentially serious side effects such as lactic acidosis are also possible. Prolonged administration may result in vitamin B12 deficiency.
Indeed, prolonged Glybir Plus G2 Tablet SR use can lead to Vitamin B12 insufficiency. This medication hinders the stomach's absorption of Vitamin B12. Left unaddressed, this deficiency might result in anemia, neurological complications, such as numbness and tingling in the extremities, muscle weakness, urinary dysfunction, cognitive impairment, and gait instability. Preventive measures proposed by some studies include annual supplemental Vitamin B12 intake.
Glybir Plus G2 Tablet SR can indeed induce hypoglycemia, characterized by low blood glucose. Manifestations of this condition may encompass nausea, headache, irritability, increased hunger, sweating, vertigo, tachycardia, and feelings of anxiety or tremor. The likelihood of hypoglycemia increases with missed or delayed meals, alcohol consumption, excessive physical activity, or concomitant use of other antidiabetic medications. Consequently, consistent blood glucose monitoring is crucial. It is advisable to always carry a rapidly absorbed sugar source, such as glucose tablets, honey, or fruit juice.
Consuming alcohol concurrently with Glybir Plus G2 Tablet SR is inadvisable due to the risk of significantly reduced blood glucose, potentially resulting in hypoglycemia. Furthermore, this combination elevates the likelihood of lactic acidosis.
Glybir Plus G2 Tablet SR
64
MRP 78
17% off