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Glyfine M 80mg/500mg Tablet

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Prescription Required

Marketer

Lifecom Pharmaceuticals Pvt Ltd

Salt Composition

Gliclazide (80mg) + Metformin (500mg)

Overview Glyfine M 80mg/500mg Tablet

Metformin/Glibenclamide 80mg/500mg tablets are classified as antidiabetic medications, combining two drugs to manage type 2 diabetes in adults. This formulation aids in regulating blood glucose. Administer this medication with food, consistently at the same time daily for optimal effectiveness. Dosage is determined by your physician and may be adjusted based on blood sugar monitoring. Continuous use is crucial, even with well-controlled blood sugar, as abrupt cessation can elevate glucose levels, potentially leading to complications including renal impairment, vision loss, neuropathy, and limb amputation. This medication forms part of a comprehensive diabetes management plan encompassing diet, physical activity, and weight management as directed by your doctor. Lifestyle choices significantly impact diabetes control. Common adverse effects include hypoglycemia (low blood sugar), characterized by sweating, dizziness, headache, and tremors; constipation; and vomiting. Regular meals and readily available glucose sources (e.g., sugary snacks, fruit juice) are essential to mitigate hypoglycemia. Alcohol consumption should be limited due to its potential to exacerbate low blood sugar. Additional potential side effects include altered taste perception, nausea, diarrhea, abdominal discomfort, and upper respiratory infections. Weight gain may occur. This medication is contraindicated in patients with type 1 diabetes, diabetic ketoacidosis, or severe hepatic or renal dysfunction. Individuals with a history of cardiovascular disease should inform their physician before commencing treatment. Consult your doctor before use during pregnancy or breastfeeding. Regular blood glucose monitoring, along with potential blood tests to assess blood cell counts and liver function, will be necessary.

Uses of Glyfine M 80mg/500mg Tablet

Diabetes mellitus type 2

Major Benefits of Glyfine M 80mg/500mg Tablet:

Follow your doctor's instructions precisely regarding dosage and treatment length for Glyfine M 80mg/500mg Tablets. Ingest the tablets whole; do not crush, chew, or break them before swallowing. Administer this medication with food.

Common Side effects of Glyfine M 80mg/500mg Tablet:

  • Hypoglycemia (low blood glucose level)
  • Headache
  • Dizziness
  • Diarrhea
  • Upper respiratory tract infection
  • Nausea
  • Flatulence
  • Constipation

How to use Glyfine M 80mg/500mg Tablet:

Consume this medication precisely as prescribed by your physician, adhering to both the dosage and treatment period. Ingest the entire tablet without chewing, crushing, or fracturing it. The Glyfine M 80mg/500mg Tablet should be administered with a meal.

How Glyfine M 80mg/500mg Tablet works:

Each Glyfine M 80mg/500mg tablet combines the antidiabetic agents gliclazide and metformin.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Combining Glyfine M 80mg/500mg Tablet and alcohol is inadvisable.

PregnancyPregnancyCONSULT YOUR DOCTOR

Use of Glyfine M 80mg/500mg tablets is contraindicated during pregnancy due to demonstrable risk to the fetus. In exceptional, life-threatening circumstances, a physician may prescribe it when the potential benefits outweigh the inherent dangers. Always seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

The use of Glyfine M 80mg/500mg tablets while breastfeeding is likely inadvisable. Available human data indicates potential transfer of the medication into breast milk, posing a risk to the infant.

DrivingDrivingCAUTION

Driving ability can be impaired by both hypoglycemia and hyperglycemia. Refrain from driving if you experience these conditions.

KidneyKidneyCAUTION

Patients with kidney impairment should exercise caution when using Glyfine M 80mg/500mg tablets, potentially requiring dosage modification. Consultation with a physician is essential. Glyfine M 80mg/500mg tablets are contraindicated in patients with severe kidney disease. Regular monitoring of renal function is recommended during treatment.

LiverLiverCAUTION

Patients with liver impairment should use Glyfine M 80mg/500mg tablets cautiously, potentially requiring dosage modification. Consult a physician. For those with mild to moderate liver disease, Glyfine M 80mg/500mg tablets should typically begin at a low dose; however, its use is contraindicated in patients with severe hepatic dysfunction.

What if you forget to take Glyfine M 80mg/500mg Tablet :

Should you forget a Glyfine M 80mg/500mg Tablet dose, administer it immediately. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing pattern. Avoid taking a double dose.

Facts to Know About Glyfine M 80mg/500mg Tablet

LabelValue
Developing Habits No.
Treatment Category Diabetes Management

FAQs on Glyfine M 80mg/500mg Tablet

Glyfine M 80mg/500mg tablets combine gliclazide and metformin to manage type 2 diabetes mellitus in adults. This combination improves blood sugar control when used with diet and exercise. Gliclazide stimulates insulin release from the pancreas, while metformin reduces liver glucose production and enhances insulin sensitivity. Glyfine M is not suitable for type 1 diabetes.
Glyfine M 80mg/500mg tablets may cause common side effects such as hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory tract infections. Rare but serious side effects, including lactic acidosis, are also possible. Prolonged use may result in vitamin B12 deficiency.
Glyfine M 80mg/500mg Tablets can cause low blood sugar (hypoglycemia), manifesting as nausea, headache, irritability, hunger, sweating, dizziness, rapid heart rate, anxiety, or shakiness. This risk increases with missed meals, alcohol consumption, excessive exercise, or concurrent use of other diabetes medications. Regular blood sugar monitoring is crucial. Carry glucose tablets, honey, or fruit juice for emergencies.
Glyfine M 80mg/500mg Tablets can cause lactic acidosis (MALA – Metformin-associated lactic acidosis), a serious medical emergency involving high blood lactic acid levels. This rare side effect is more likely in patients with kidney disease, older adults, or those who consume excessive alcohol. Symptoms include muscle pain or weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If you experience these, discontinue Glyfine M and seek immediate medical attention.
Prolonged Glyfine M 80mg/500mg Tablet use can lead to vitamin B12 deficiency by hindering its absorption in the stomach. This deficiency, if left untreated, may result in anemia, neurological issues such as tingling, numbness in extremities, weakness, urinary problems, cognitive changes, and balance difficulties (ataxia). To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Glyfine M 80mg/500mg Tablets are contraindicated in patients with allergies to any ingredient or excipient, and in those with moderate to severe kidney disease or metabolic acidosis (including diabetic ketoacidosis).
Combining Glyfine M 80mg/500mg tablets and alcohol is unsafe. Alcohol can worsen low blood sugar and raise the risk of lactic acidosis.
Glyfine M 80mg/500mg tablets combine gliclazide and metformin to manage type 2 diabetes mellitus in adults. This medication improves blood sugar control when used with diet and exercise. Gliclazide stimulates insulin release from the pancreas, while metformin reduces liver glucose production and enhances insulin sensitivity. It's not suitable for type 1 diabetes.
Glyfine M 80mg/500mg tablets may cause common side effects such as hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory tract infections. Rare but serious side effects, including lactic acidosis, are also possible. Prolonged use may result in vitamin B12 deficiency.
Glyfine M 80mg/500mg Tablets can cause low blood sugar (hypoglycemia), manifesting as nausea, headache, irritability, hunger, sweating, dizziness, rapid heart rate, anxiety, or shakiness. This risk increases with missed meals, alcohol consumption, excessive exercise, or concurrent use of other diabetes medications. Regular blood sugar monitoring is crucial. Carry glucose tablets, honey, or fruit juice to treat low blood sugar.
Glyfine M 80mg/500mg Tablets can cause lactic acidosis, a serious medical emergency characterized by excessive blood lactic acid (also known as Metformin-associated lactic acidosis or MALA). This rare side effect is less likely to occur if you avoid using the medication with pre-existing kidney disease, advanced age, or heavy alcohol consumption. Symptoms such as muscle pain or weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, or a slow heart rate require immediate medical attention. Stop taking Glyfine M and contact your doctor immediately if you experience any of these.
Prolonged Glyfine M 80mg/500mg Tablet use can lead to vitamin B12 deficiency by impairing its stomach absorption. This deficiency, if left untreated, may result in anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, and balance problems – ataxia), urinary issues, and cognitive changes. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Glyfine M 80mg/500mg Tablets are contraindicated in patients with allergies to any ingredient or excipient, and in those with moderate to severe kidney disease or metabolic acidosis (including diabetic ketoacidosis).
Consuming alcohol while taking Glyfine M 80mg/500mg tablets is unsafe. It can worsen low blood sugar and raise the risk of lactic acidosis.
Glyfine M 80mg/500mg Tabl...
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MRP 50
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