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Golbi SR 450 Tablet

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Prescription Required

Marketer

Intas Pharmaceuticals Ltd

Salt Composition

Ursodeoxycholic Acid (450mg)

Overview Golbi SR 450 Tablet

Ursodiol 450mg extended-release tablets are indicated for dissolving gallstones and preventing their recurrence. They are also prescribed for primary biliary cholangitis, aiding in the breakdown of cholesterol-based gallstones. The tablets should be ingested whole with food and a beverage, such as milk or water. Dosage is individualized based on the condition being treated and patient weight. Consistent daily use, as directed (often for months or longer), is crucial for optimal results; continuation is advised even after symptom resolution. Common side effects, though not experienced by all patients, include abdominal discomfort, diarrhea, alopecia, pruritus, nausea, and skin rashes. Consult your physician if side effects are concerning or persistent. Prior to commencing treatment, inform your doctor of any gallbladder or bile duct inflammation, recurrent upper abdominal cramping, hemoptysis, or recent significant weight gain. Concurrent medication use may be affected; therefore, disclose all other medications to your doctor. Women should cease hormonal contraception, as it may exacerbate gallstone formation. Regular liver function tests and ultrasound examinations may be necessary during treatment.

Primary Ingredients of Golbi SR 450 Tablet

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Uses of Golbi SR 450 Tablet

Managing primary biliary cholangitis | Addressing cholelithiasis

Major Benefits of Golbi SR 450 Tablet:

Consume this medication precisely as directed by your physician, adhering to the prescribed dosage and treatment schedule. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Golbi SR 450 Tablets should be administered with a meal.

Common Side effects of Golbi SR 450 Tablet:

  • Abdominal pain
  • Diarrhea
  • Hair loss
  • Itching
  • Nausea
  • Rash

How to use Golbi SR 450 Tablet:

Consume this medication precisely as your physician directs, adhering to both the prescribed dosage and treatment length. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Golbi SR 450 Tablets should be administered with a meal.

How Golbi SR 450 Tablet works:

HepatoGuard 450mg tablets offer hepatoprotective benefits. This medication lowers blood cholesterol levels, aiding in the dissolution of cholesterol-based gallstones. Furthermore, it enhances liver enzyme function, safeguards liver cells against bile acid toxicity, and promotes overall liver health.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Concurrent use of Golbi SR 450 Tablet and alcohol can lead to increased sleepiness.

PregnancyPregnancySAFE IF PRESCRIBED

The use of Golbi SR 450 Tablet during pregnancy is generally deemed safe. Preclinical trials in animals have revealed minimal or no negative impact on fetal development; nevertheless, data from human studies are scarce.

Breast feedingBreast feedingSAFE IF PRESCRIBED

Extended-release Golbi 450 mg tablets appear to pose minimal breastfeeding risk. Available human data indicates negligible infant hazard from this medication.

DrivingDrivingSAFE

Driving ability is typically unaffected by Golbi SR 450 Tablet.

KidneyKidneyCONSULT YOUR DOCTOR

Data on Golbi SR 450 Tablet use in patients with impaired renal function is scarce. Physician consultation is advised.

LiverLiverCONSULT YOUR DOCTOR

Insufficient data exists regarding Golbi SR 450 Tablet use in individuals with hepatic impairment. Physician consultation is advised.

What if you forget to take Golbi SR 450 Tablet :

Omit any missed Golbi SR 450 Tablet dose and resume your usual medication regimen. Avoid taking a double dose.

Facts to Know About Golbi SR 450 Tablet

LabelValue
Chemical Category Biliary Acids and Salts
Developing Habits No.
Treatment Category Gastrointestinal system
Behavior Class Liver protectants

FAQs on Golbi SR 450 Tablet

Dosage and timing for Golbi SR 450 Tablet vary depending on your condition. Your doctor may prescribe 2-3 doses daily, possibly with the last dose at bedtime. Take it with water or milk, with or without food. For gallstones, a single nightly dose is typical. If taking multiple doses, maintain a 6-hour interval (e.g., 8 am, 2 pm, 8 pm).
Golbi SR 450 Tablets are generally safe and effective. While diarrhea is a possible side effect, your doctor can adjust the dosage or discontinue treatment if necessary. Long-term use may impact liver enzyme levels, requiring regular monitoring. Nevertheless, it offers a viable non-surgical option for some gallstone patients.
Golbi SR 450 Tablets work by concentrating in the liver's bile, inhibiting cholesterol synthesis and secretion, and lowering bile cholesterol levels. The drug also reduces intestinal absorption of bile salts and cholesterol. This decreased bile cholesterol saturation facilitates gallstone dissolution, shrinking them and potentially eliminating them. Furthermore, increased bile flow protects liver cells by reducing elevated liver enzyme levels.
Weight gain is a possible, though uncommon, side effect of Golbi SR 450 Tablet. It's more likely in patients with liver disease causing bile stasis, preventing bile flow to the intestines. However, individual responses vary, so consult your doctor about any weight gain.
To maximize the effectiveness of Golbi SR 450 Tablet, avoid antacids, cholestyramine, colestipol, oral contraceptives, estrogenic hormones, and clofibrate without first discussing it with your doctor. These medications can reduce Golbi SR 450 Tablet's efficacy or increase the risk of gallstones. Your doctor can advise on appropriate timing if you must take these medications concurrently.
Golbi SR 450 Tablet
704
MRP 857
17% off