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Griknil-M1 Tablet SR

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Prescription Required

Marketer

Aplonis Healthcare

Salt Composition

Glimepiride (1mg) + Metformin (500mg)

Overview Griknil-M1 Tablet SR

Diabex Duo SR tablets are a dual-action antidiabetic medication prescribed for adult patients with type 2 diabetes. This formulation combines two active ingredients to effectively manage blood glucose levels. Diabex Duo SR should be ingested with food, consistently at the same time daily for optimal efficacy. Dosage is determined by your physician and may be adjusted based on blood sugar monitoring. Continuous use is crucial, even with controlled blood sugar, as abrupt cessation can lead to elevated glucose levels, potentially causing kidney complications, vision impairment, neuropathy, and limb loss. This medication forms part of a comprehensive treatment plan, encompassing dietary modifications, regular exercise, and weight management as directed by your healthcare provider. Lifestyle choices significantly impact diabetes control. Hypoglycemia (low blood sugar) is the most frequent adverse effect. Learn to identify its symptoms, including sweating, lightheadedness, headache, and trembling, and know how to treat it promptly. Maintain regular mealtimes and carry a fast-acting glucose source like candy or juice. Alcohol consumption elevates hypoglycemia risk and should be minimized. Additional possible side effects include altered taste perception, nausea, diarrhea, abdominal discomfort, headache, and upper respiratory infections. Weight gain may occur in some patients. This medication is contraindicated in patients with type 1 diabetes, diabetic ketoacidosis, or severe hepatic or renal impairment. Individuals with a history of cardiovascular disease should inform their doctor before commencing treatment. Pregnant or lactating women require medical consultation prior to use. Regular blood glucose monitoring is essential, and your doctor may order blood tests to assess blood cell counts and liver function.

Uses of Griknil-M1 Tablet SR

Managing type 2 diabetes

Major Benefits of Griknil-M1 Tablet SR:

Consume this medication according to your physician's prescribed dosage and schedule. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Griknil-M1 Tablet SR should be administered with a meal.

Common Side effects of Griknil-M1 Tablet SR:

  • Headache
  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Diarrhea

How to use Griknil-M1 Tablet SR:

Consume this medication precisely as directed by your physician, adhering to the prescribed dosage and treatment period. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Griknil-M1 SR tablets should be administered with a meal.

How Griknil-M1 Tablet SR works:

Griknil-M1 SR tablets contain a dual-action antidiabetic formulation: glimepiride and metformin. Glimepiride, a sulfonylurea, enhances pancreatic insulin secretion, thus reducing blood sugar. Metformin, a biguanide, acts by decreasing hepatic glucose production, slowing intestinal glucose uptake, and improving insulin responsiveness.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Concurrent use of Griknil-M1 Tablet SR and alcohol is inadvisable.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Griknil-M1 Tablet SR during pregnancy may pose risks. While human research is scarce, animal studies indicate potential harm to the fetus. A physician will assess the potential advantages against the risks before recommending its use. Medical advice is recommended.

Breast feedingBreast feedingUNSAFE

Extended-release Griknil-M1 tablets are contraindicated for breastfeeding mothers due to the potential for infant toxicity.

DrivingDrivingCAUTION

Driving ability can be impaired by both hypoglycemia and hyperglycemia. Refrain from driving if you experience these conditions.

KidneyKidneyCAUTION

Patients with kidney impairment should use Griknil-M1 Tablet SR cautiously, potentially requiring dosage modification. Physician consultation is advised. Griknil-M1 Tablet SR is contraindicated in patients with severe renal dysfunction. Regular kidney function assessments are recommended during treatment.

LiverLiverCAUTION

Exercise caution when prescribing Griknil-M1 SR tablets to individuals with hepatic impairment; dosage modification may be necessary. Physician consultation is advised. For patients exhibiting mild to moderate liver dysfunction, initiate Griknil-M1 SR tablet therapy at a reduced dosage; the medication is contraindicated in those with severe liver disease.

What if you forget to take Griknil-M1 Tablet SR :

Should you forget a Griknil-M1 Tablet SR dose, take it immediately. If your next dose is nearly due, however, omit the missed dose and resume your usual regimen. Never take a double dose.

Facts to Know About Griknil-M1 Tablet SR

LabelValue
Potential for Dependence None.
Type of Medication Medication for diabetes

FAQs on Griknil-M1 Tablet SR

Retain this medication within its original, securely sealed container. Follow the storage guidelines provided on the packaging or label. Discard any remaining medication. Prevent access by children, pets, and others.
Indeed, Griknil-M1 Tablet SR carries a risk of inducing lactic acidosis, a serious medical condition characterized by excessive lactic acid in the bloodstream. Also termed Metformin-associated lactic acidosis (MALA), this is an infrequent adverse reaction linked to metformin use. Consequently, it poses a significant risk to individuals with pre-existing kidney impairment, the elderly, or those who consume substantial quantities of alcohol. Lactic acidosis symptoms can manifest as muscle aches or weakness, vertigo, fatigue, cold extremities, dyspnea, nausea, emesis, abdominal discomfort, or bradycardia. Should these symptoms arise, discontinue Griknil-M1 Tablet SR and seek immediate medical attention.
Glimepiride and Metformin, combined as Griknil-M1 Tablet SR, manage type 2 diabetes mellitus (DM) in adults. This medication enhances blood sugar control when coupled with a suitable diet and physical activity. Glimepiride functions by stimulating the pancreas to release more insulin, thus reducing blood glucose. Metformin acts by decreasing hepatic glucose production and increasing insulin responsiveness. This formulation is unsuitable for type 1 DM.
Griknil-M1 SR tablets may cause common side effects including low blood sugar (hypoglycemia), taste disturbances, nausea, abdominal pain, diarrhea, and headache. Rare but serious adverse reactions such as lactic acidosis are also possible. Prolonged use may result in vitamin B12 deficiency.
Prolonged Griknil-M1 Tablet SR use can indeed lead to Vitamin B12 deficiency by hindering its gastric absorption. This deficiency, if left unaddressed, may manifest as anemia, neurological issues including paresthesia in the extremities, generalized weakness, urinary dysfunction, cognitive impairment, and ataxia. Preventive measures, proposed by some studies, involve supplemental Vitamin B12 at least annually.
Griknil-M1 Tablet SR can indeed lower blood glucose levels, resulting in hypoglycemia. Low blood sugar manifests as nausea, headache, irritability, hunger pangs, sweating, dizziness, tachycardia, and feelings of anxiety or tremors. This risk increases with skipped or delayed meals, alcohol consumption, excessive physical activity, or concurrent use of other antidiabetic medications. Therefore, consistent blood glucose monitoring is crucial. Carrying a readily available fast-acting sugar source, such as glucose tablets, honey, or fruit juice, is recommended.
Combining Griknil-M1 Tablet SR and alcohol is unsafe due to the risk of dangerously low blood sugar (hypoglycemia). This combination also raises the likelihood of lactic acidosis.
Griknil-M1 Tablet SR
44
MRP 53
16% off