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Imat 400 Tablet

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Prescription Required

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Zydus Healthcare Limited

Salt Composition

Imatinib mesylate (400mg)

Overview Imat 400 Tablet

Imatinib 400mg tablets are indicated for various cancers. Primary uses include blood cancers such as chronic myeloid leukemia and acute lymphocytic leukemia, plus gastrointestinal stromal tumors. Its mechanism involves targeting proteins crucial for cancer cell proliferation and metastasis. This medication also treats dermatofibrosarcoma protuberans (a skin tumor) and aggressive systemic mastocytosis (a bone marrow disorder). Administer with food, consistently at the same time daily for optimal efficacy. Treatment duration is individualized based on response and medical need. Incorrect usage or overdose may lead to severe adverse effects. Therapeutic benefits may not be apparent for weeks or months; discontinue only under physician guidance. Common side effects include swelling, nausea, vomiting, muscle spasms, musculoskeletal discomfort, diarrhea, skin rash, tiredness, and stomach pain. Report any sudden, significant weight gain. Regular blood counts and liver function tests are often recommended. Avoid driving or activities demanding concentration if dizziness or blurred vision occur. Inform your healthcare provider of all other medications, as interactions are possible. This medication is contraindicated during pregnancy and breastfeeding; reliable contraception is essential for both partners throughout treatment.

Uses of Imat 400 Tablet

Oncological Management

Major Benefits of Imat 400 Tablet:

Consume this medication precisely as your physician directs, adhering to the prescribed dosage and treatment period. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. The Imat 400 Tablet should be administered with a meal.

Common Side effects of Imat 400 Tablet:

  • Edema (swelling)
  • Nausea
  • Vomiting
  • Muscle cramp
  • Musculoskeletal (bone, muscle or joint) pain
  • Diarrhea
  • Rash
  • Fatigue
  • Abdominal pain
  • Bleeding
  • Breathing problems
  • Cough
  • Weight gain
  • Dry eye
  • Dizziness
  • Hemorrhage

How to use Imat 400 Tablet:

Consume this medication precisely as your physician directs, adhering to both the prescribed dosage and treatment period. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. The Imat 400 Tablet should be administered with a meal.

How Imat 400 Tablet works:

Imatinib 400 mg tablets combat cancer by targeting the bcr-abl tyrosine kinase enzyme. This enzyme drives the uncontrolled growth of cancerous cells. The medication blocks this enzyme's activity, thus preventing cell proliferation and triggering programmed cell death in bcr-abl positive leukemia cells, effectively hindering or slowing cancer progression.

SAFETY ADVICE

AlcoholAlcoholCONSULT YOUR DOCTOR

Alcohol consumption alongside Imat 400 Tablet is not known to be safe. Seek medical advice before combining them.

PregnancyPregnancyCONSULT YOUR DOCTOR

Using Imat 400 Tablet during pregnancy poses a confirmed risk to the fetus. Therefore, its use is inadvisable. Nevertheless, in exceptional, life-threatening circumstances, a physician might prescribe it if the potential advantages outweigh the known hazards. Physician consultation is essential.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Using Imat 400 Tablet while breastfeeding is likely unsafe. Available human data indicates potential transfer to breast milk, posing a risk to the infant. Nursing mothers should discontinue breastfeeding during treatment and for two weeks following cessation.

DrivingDrivingUNSAFE

Driving ability may be impaired by side effects associated with Imat 400 Tablet.

KidneyKidneyCAUTION

Patients with impaired kidney function should use Imat 400 Tablet cautiously. Dosage modification for Imat 400 Tablet might be necessary. Physician consultation is advised.

LiverLiverCAUTION

Patients with severe hepatic impairment should exercise caution when using Imat 400 Tablets. Dosage modification may be necessary; physician consultation is recommended.

What if you forget to take Imat 400 Tablet :

Omit any missed Imat 400 Tablet dose and resume your regular medication schedule; avoid taking a double dose.

Facts to Know About Imat 400 Tablet

LabelValue
Chemical Category Benzanilide Derivative
Developing Habits No.
Treatment Category Cancer Medications
Action Category Kinase inhibitors targeting tyrosine

FAQs on Imat 400 Tablet

For best results, take with food and a glass of water to minimize stomach irritation. If swallowing is difficult, dissolve the tablet in 50ml of water or apple juice (for 100mg tablets) or 200ml (for 400mg tablets). Stir until dissolved and drink immediately.
Imat 400 Tablets may cause dizziness, lightheadedness, or drowsiness. Drive or operate machinery only after assessing your individual response to the medication.
Strictly adhere to your doctor's instructions for Imat 400 Tablet, attending all scheduled appointments. Regular monitoring, including blood tests, weight checks, and urine tests, is crucial to detect potential side effects early. Use contraception throughout treatment; inform your doctor immediately if pregnancy occurs. Always inform your doctor about Imat 400 Tablet use before starting any new medication.
This medication can significantly increase your skin's sun sensitivity, potentially leading to rash, itching, redness, or severe sunburn. Always wear protective clothing and a sunscreen with SPF 15 or higher when outdoors. Report any skin burning to your doctor immediately.
Imat 400 Tablet interacts with several medications, such as paracetamol, cyclosporin, dexamethasone, warfarin, antiviral and antibacterial drugs, and medications for high cholesterol, blood pressure, heart conditions, mental health disorders, and depression. Avoid self-medicating while taking Imat 400 Tablet. Always consult your doctor before starting any new medication, informing them of your Imat 400 Tablet treatment.
Imatinib 400mg tablets have shown effectiveness in numerous chronic myeloid leukemia (CML) cases, often improving survival rates. Your physician, considering your condition, blood work, treatment response, and other health factors, can best advise on its suitability for you.
Imat 400 Tablet
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