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Imatikast 400mg Tablet

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Aprazer Healthcare Pvt Ltd

Salt Composition

Imatinib mesylate (400mg)

Overview Imatikast 400mg Tablet

Imatinib 400mg tablets are indicated for various cancers. Primarily, it's prescribed for hematologic malignancies such as chronic myeloid leukemia and acute lymphoblastic leukemia, along with gastrointestinal stromal tumors. Its mechanism involves targeting proteins crucial for cancer cell proliferation and metastasis. This medication also treats dermatofibrosarcoma protuberans (a skin tumor) and aggressive systemic mastocytosis (a bone marrow disorder). Administer this medication with food, consistently at the same time daily for optimal efficacy. Continue treatment as directed by your physician; duration is individualized based on response and needs. Incorrect usage or overdose can lead to severe adverse effects. Therapeutic benefits may not be apparent for weeks or months; discontinue only with your doctor's instruction. Common side effects include edema, nausea, vomiting, muscle spasms, musculoskeletal pain, diarrhea, rash, tiredness, and stomach pain. Report any sudden, significant weight gain. Regular blood count and liver function tests may be recommended. Avoid activities requiring alertness if dizziness or blurred vision occur. Inform your healthcare provider of all other medications, as interactions are possible. This medicine is contraindicated during pregnancy and lactation; reliable contraception is essential for both partners throughout the treatment period.

Uses of Imatikast 400mg Tablet

Oncological Care

Major Benefits of Imatikast 400mg Tablet:

Consume this medication precisely as directed by your physician, adhering to the prescribed dosage and treatment period. Ingest the 400mg Imatikast tablet whole; avoid chewing, crushing, or fracturing it. Administer this medication with food.

Common Side effects of Imatikast 400mg Tablet:

  • Edema (swelling)
  • Nausea
  • Vomiting
  • Muscle cramp
  • Musculoskeletal (bone, muscle or joint) pain
  • Diarrhea
  • Rash
  • Fatigue
  • Abdominal pain
  • Bleeding
  • Breathing problems
  • Cough
  • Weight gain
  • Dry eye
  • Dizziness
  • Hemorrhage

How to use Imatikast 400mg Tablet:

Follow your doctor's instructions precisely regarding dosage and treatment length for this medication. Ingest the 400mg Imatikast tablet whole; avoid chewing, crushing, or breaking it. Administer this medicine with food.

How Imatikast 400mg Tablet works:

Imatikast 400mg tablets combat cancer by targeting the bcr-abl tyrosine kinase enzyme. This protein drives the uncontrolled growth of cancerous cells. By inhibiting this enzyme, Imatikast halts the proliferation of bcr-abl-positive cancer cells and triggers their programmed self-destruction (apoptosis), thus controlling or slowing cancer progression.

SAFETY ADVICE

AlcoholAlcoholCONSULT YOUR DOCTOR

Alcohol consumption alongside Imatikast 400mg Tablet may pose unknown risks. Seek medical advice before combining them.

PregnancyPregnancyCONSULT YOUR DOCTOR

Use of Imatikast 400mg tablets is contraindicated during pregnancy due to established harm to the fetus. Nevertheless, a physician might exceptionally prescribe it in critical circumstances where the potential advantages outweigh the risks. Seek medical advice before use.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

The use of Imatikast 400mg tablets while breastfeeding is likely inadvisable. Available human data indicates potential transfer to breast milk, posing a risk to the infant. Nursing mothers should discontinue breastfeeding during treatment and for a further 15 days following cessation of Imatikast.

DrivingDrivingUNSAFE

Driving ability may be impaired by the use of Imatikast 400mg Tablets, due to potential side effects.

KidneyKidneyCAUTION

Patients with kidney impairment should use Imatikast 400mg tablets cautiously, as dose modification may be necessary. Physician consultation is recommended.

LiverLiverCAUTION

Patients with severe hepatic impairment should use Imatikast 400mg tablets cautiously; dosage modification may be necessary. Physician consultation is recommended.

What if you forget to take Imatikast 400mg Tablet :

Omit any missed Imatikast 400mg Tablet dose and resume your usual medication regimen. Avoid taking a double dose.

Facts to Know About Imatikast 400mg Tablet

LabelValue
Pharmaceutical Category Anilide-based benzamide
Potential for Dependence None.
Type of Medication Cancer-fighting drugs
Mechanism of Action Kinase inhibitors targeting tyrosine

FAQs on Imatikast 400mg Tablet

Optimal administration involves ingestion with water and food to minimize esophageal and gastric discomfort. If swallowing the tablets proves difficult, dissolve them in 50 ml of water or apple juice for a 100 mg tablet, or 200 ml for a 400 mg tablet. Stir thoroughly to ensure complete dissolution before immediate consumption.
Taking a 400mg Imatikast tablet might induce dizziness, lightheadedness, or drowsiness. It's crucial to assess your personal reaction to the medication before driving or using equipment.
Adhere strictly to your physician's instructions and attend all scheduled appointments when using Imatikast 400mg Tablets. Consistent monitoring is crucial to assess treatment efficacy. This may involve routine blood work, weight monitoring, and urinalysis to detect potential adverse reactions early. Employ reliable contraception throughout your Imatikast 400mg Tablet treatment. Report any pregnancy immediately to your doctor. Always inform your doctor about your Imatikast 400mg Tablet use before commencing any new medication.
This medication can significantly increase your skin's sensitivity to sun exposure. Sunlight may result in a skin rash, itching, redness, or intense sunburn. While outside, wear protective garments and apply a sunscreen with an SPF of 15 or greater. Report any skin burning to your physician immediately.
Imatikast 400mg Tablet interacts with several medications, such as paracetamol, requiring avoidance of self-medication during treatment. Concurrent use with cyclosporine, dexamethasone, warfarin, antivirals for AIDS, and various drugs treating bacterial infections, high cholesterol, hypertension, cardiovascular disease, and mental health conditions is also contraindicated. Always consult your physician before starting any new medication, disclosing your Imatikast 400mg Tablet regimen.
In numerous instances of chronic myeloid leukemia (CML), the 400mg Imatikast tablet has demonstrated efficacy. Improved survival rates have also been observed following its administration. For a comprehensive assessment, consultation with your CML specialist is recommended. They will consider your overall health, blood work, treatment response, and any co-existing conditions to provide personalized guidance.
Imatikast 400mg Tablet
1,982
MRP 2,300
13% off