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Imatinib 400 Tablet

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Sun Pharmaceutical Industries Ltd

Salt Composition

Imatinib mesylate (400mg)

Overview Imatinib 400 Tablet

Gleevec 400mg tablets combat various cancers, primarily blood cancers like chronic myeloid leukemia and acute lymphoblastic leukemia, as well as gastrointestinal stromal tumors. Its mechanism involves targeting specific proteins crucial to cancerous cell proliferation and metastasis. This medication also treats dermatofibrosarcoma protuberans (a skin tumor) and aggressive systemic mastocytosis (a bone marrow disorder). Administer with food, consistently at the same time daily for optimal efficacy. Continue treatment as directed by your physician; duration depends on individual needs and response. Incorrect usage or overdose can lead to severe adverse effects. Therapeutic benefits may take weeks or months to manifest; discontinue only under physician guidance. Common side effects include swelling, nausea, vomiting, muscle spasms, musculoskeletal pain, diarrhea, skin rashes, tiredness, and stomach pain. Report unexplained rapid weight gain to your doctor. Regular blood counts and liver function tests may be recommended. Avoid activities requiring alertness if dizziness or blurred vision occur. Inform your healthcare provider of all other medications being taken, as interactions are possible. This medication is contraindicated during pregnancy and breastfeeding; effective contraception is crucial for both partners during treatment.

Uses of Imatinib 400 Tablet

Oncological Management

Major Benefits of Imatinib 400 Tablet:

Follow your doctor's instructions precisely regarding the dosage and treatment length for this medication. Ingest the Imatinib 400mg tablet whole; avoid chewing, crushing, or breaking it. Administer this medication with a meal.

Common Side effects of Imatinib 400 Tablet:

  • Edema (swelling)
  • Nausea
  • Vomiting
  • Muscle cramp
  • Musculoskeletal (bone, muscle or joint) pain
  • Diarrhea
  • Rash
  • Fatigue
  • Abdominal pain
  • Bleeding
  • Breathing problems
  • Cough
  • Weight gain
  • Dry eye
  • Dizziness
  • Hemorrhage

How to use Imatinib 400 Tablet:

Consume this medication precisely as your physician directs, adhering to both the prescribed dosage and duration. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. The Imatinib 400mg tablet should be administered with food.

How Imatinib 400 Tablet works:

Imatinib 400 mg tablets combat cancer by targeting the bcr-abl tyrosine kinase enzyme. This protein drives uncontrolled cancer cell growth, but imatinib blocks its activity. Consequently, the drug suppresses the multiplication of bcr-abl-positive cancer cells and triggers their programmed self-destruction (apoptosis), thus hindering or halting cancer progression.

SAFETY ADVICE

AlcoholAlcoholCONSULT YOUR DOCTOR

The interaction of alcohol with Imatinib 400 Tablet is unknown; seek medical advice before combining them.

PregnancyPregnancyCONSULT YOUR DOCTOR

Using Imatinib 400mg tablets during pregnancy poses a confirmed risk to the fetus. Nevertheless, in exceptional life-threatening circumstances, a physician might prescribe it if the potential benefits outweigh the known hazards. Always seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Breastfeeding while taking Imatinib 400mg tablets is likely unsafe. Available data in humans indicates potential drug transfer to breast milk, posing a risk to the infant. Nursing mothers should discontinue breastfeeding during treatment and for a fortnight following cessation of Imatinib.

DrivingDrivingUNSAFE

Driving ability may be impaired by side effects associated with Imatinib 400 mg tablets.

KidneyKidneyCAUTION

Patients with kidney impairment should use Imatinib 400 mg tablets cautiously; dosage modification may be necessary. Physician consultation is advised.

LiverLiverCAUTION

Patients with severe hepatic impairment should use Imatinib 400 mg tablets cautiously. Dosage modification may be necessary; physician consultation is advised.

What if you forget to take Imatinib 400 Tablet :

Omit any missed Imatinib 400 Tablet dose and resume your usual medication regimen. Avoid taking a double dose.

Facts to Know About Imatinib 400 Tablet

LabelValue
Chemical Category Benzanilide Derivative
Developing Habits No.
Treatment Category Cancer Medications
Behavior Class TKIs (tyrosine kinase inhibitors)

FAQs on Imatinib 400 Tablet

For best results, take with food and a glass of water to minimize stomach and esophageal irritation. If swallowing is difficult, dissolve the tablet in 50ml of water or apple juice (for 100mg tablets) or 200ml (for 400mg tablets). Stir until dissolved and drink immediately.
Imatinib 400 mg tablets can cause dizziness, lightheadedness, or drowsiness. Drive or operate machinery only after assessing your response to this medication.
Strictly adhere to your doctor's instructions and attend all scheduled appointments while taking Imatinib 400mg tablets. Regular monitoring, including blood, urine, and weight checks, is crucial to detect and manage potential side effects promptly. Use contraception throughout treatment and immediately inform your doctor if pregnancy occurs. Always inform your doctor of any new medications you intend to start while taking Imatinib 400mg tablets.
This medication can significantly increase your skin's sun sensitivity, potentially leading to rash, itching, redness, or severe sunburn. Always wear protective clothing and a sunscreen with SPF 15 or higher when outdoors. Report any skin burning to your doctor immediately.
Imatinib 400 Tablet interacts with many medications, such as paracetamol, cyclosporin, dexamethasone, warfarin, antivirals (for AIDS), and drugs for bacterial infections, high cholesterol, high blood pressure, heart conditions, mental health disorders, and depression. Avoid self-medicating while taking Imatinib 400 Tablet. Always consult your doctor before starting any new medication and inform them you're using Imatinib 400 Tablet.
Imatinib 400mg tablets have shown effectiveness in numerous chronic myeloid leukemia (CML) cases, often improving survival rates. Your physician, considering your condition, blood work, treatment response, and other health factors, can best determine its suitability for you.
Imatinib 400 Tablet
1,033
MRP 1,199
13% off