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ISOCIN 450MG/300MG TABLET

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Prescription Required

Marketer

Zee Laboratories

Salt Composition

Rifampicin (450mg) + Isoniazid (300mg)

Overview ISOCIN 450MG/300MG TABLET

Combiflox 450mg/300mg tablets combat tuberculosis by inhibiting the growth of causative bacteria. This prescription medication, taken as directed by your physician, should be ingested on an empty stomach at a consistent time for optimal effectiveness. Exceeding the prescribed dosage can be harmful. Missed doses should be taken as soon as remembered. Complete the entire course of treatment, even with symptom improvement, as premature cessation may reduce efficacy. Therapeutic effects may take time to manifest. Consult your doctor if symptoms worsen or fail to improve. Common side effects include nausea, vomiting, fever, dark urine, sweating, increased salivation, etc. Hydration is crucial to manage these effects; consult your doctor if they worsen. Serious side effects are uncommon. Seek immediate medical attention for allergic reactions (rash, itching, swelling, shortness of breath). Inform your doctor about all other medications before starting this treatment. Patients with liver or kidney issues require careful monitoring and consultation. Pregnant or breastfeeding women should consult their doctor. Alcohol should be avoided due to potential drowsiness. While generally not impairing driving ability, avoid driving if drowsiness or dizziness occurs. Adequate rest and a healthy diet promote faster recovery. Your doctor may order tests to monitor the medicine's effects.

Uses of ISOCIN 450MG/300MG TABLET

Managing Tuberculosis (TB)

Major Benefits of ISOCIN 450MG/300MG TABLET:

Follow your doctor's instructions precisely regarding dosage and treatment length for this medication. Ingest the ISOCIN 450MG/300MG TABLET whole; do not break, crush, or chew it. Administer this tablet on an empty stomach. Refrain from consuming tyramine-rich foods, including aged cheese, cured meats, smoked fish, and certain beers, while taking ISOCIN 450MG/300MG TABLET.

Common Side effects of ISOCIN 450MG/300MG TABLET:

  • Dark colored urine
  • Rash
  • Vomiting
  • Jaundice
  • Fever
  • Increased liver enzymes
  • Nausea
  • Peripheral neuropathy (tingling and numbness of feet and hand)

How to use ISOCIN 450MG/300MG TABLET:

Administer this medication precisely as your physician directs, adhering to the prescribed dosage and treatment length. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Consume ISOCIN 450MG/300MG TABLETS on an empty stomach. Refrain from consuming ISOCIN 450MG/300MG TABLETS alongside foods high in tyramine, including certain cheeses, smoked seafood, various meats, and some beers.

How ISOCIN 450MG/300MG TABLET works:

Each ISOCIN 450MG/300MG tablet combines rifampicin and isoniazid, two antibiotics effective against tuberculosis (TB). Rifampicin disables a crucial bacterial enzyme (RNA polymerase), halting TB bacteria's protein synthesis and reproduction. Isoniazid simultaneously disrupts the bacteria's protective shell. This dual action ensures bacterial elimination and infection resolution.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Concurrent use of ISOCIN 450MG/300MG TABLET and alcohol can trigger adverse reactions including facial flushing, tachycardia, nausea, thirst, chest discomfort, and hypotension (a disulfiram-like effect).

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of ISOCIN 450MG/300MG TABLET during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to the fetus. A physician will assess the potential advantages against possible risks prior to prescribing. Seek medical advice before taking this medication.

Breast feedingBreast feedingSAFE IF PRESCRIBED

Lactating individuals may safely use ISOCIN 450MG/300MG TABLETS. Research in humans indicates negligible transfer of the medication into breast milk, posing no apparent risk to the infant.

DrivingDrivingUNSAFE

Taking ISOCIN 450MG/300MG TABLETS may induce adverse reactions that impair driving capabilities. These reactions can include seizures, psychiatric disturbances, and optic neuritis (optic nerve inflammation potentially leading to vision loss), all of which could affect your ability to drive safely.

KidneyKidneyCAUTION

Patients with kidney impairment should use ISOCIN 450MG/300MG TABLETS cautiously. Dosage modification may be necessary; physician consultation is advised.

LiverLiverCAUTION

Patients with liver impairment should use ISOCIN 450MG/300MG TABLETS cautiously, potentially requiring dosage modification. Physician consultation is advised. ISOCIN 450MG/300MG TABLETS are contraindicated in individuals with severe hepatic dysfunction.

What if you forget to take ISOCIN 450MG/300MG TABLET :

Should you forget to take your ISOCIN 450MG/300MG TABLET, administer it promptly. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About ISOCIN 450MG/300MG TABLET

LabelValue
Developing Good Habits No.
Treatment Category Infectious Disease Treatments

FAQs on ISOCIN 450MG/300MG TABLET

ISOCIN 450MG/300MG TABLETS combine rifampicin and isoniazid to treat tuberculosis. Rifampicin disables a vital bacterial enzyme (RNA polymerase), halting protein synthesis and bacterial reproduction. Isoniazid prevents the tuberculosis bacteria from building a protective shell. This combined action kills the bacteria and eliminates the infection.
Follow your prescribed medication regimen precisely; don't discontinue it prematurely, even if you feel improved. Refrain from alcohol consumption during treatment, as it elevates the risk of liver damage. Report any vision changes, appetite loss, fatigue, abdominal pain, nausea or vomiting, jaundice (yellowing of skin or eyes), or dark urine to your doctor immediately.
Follow your doctor's instructions precisely when taking ISOCIN 450MG/300MG TABLETS. For best results, take them on an empty stomach, one hour before or two hours after eating.
Yes, ISOCIN 450MG/300MG tablets may temporarily turn your urine, skin, sweat, saliva, tears, and feces brownish-red or orange. This is harmless.
Yes, ISOCIN 450MG/300MG TABLETS can reduce the effectiveness of birth control pills. Therefore, discuss alternative, non-hormonal birth control options like condoms, diaphragms, and spermicides with your doctor.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication and keep it out of reach of children, pets, and others.
ISOCIN 450MG/300MG TABLET
49
MRP 57
14% off