Search Icon

AUM Pharmacy

Hi there!

Hello, Login
All Categories
VisaVisaVisa
fallback

Isorif 450mg/300mg Tablet

Prescription Icon
Prescription Required

Marketer

Dyochem Laboratories

Salt Composition

Rifampicin (450mg) + Isoniazid (300mg)

Overview Isorif 450mg/300mg Tablet

Rifampicin and Isoniazid 450mg/300mg tablets combat tuberculosis by inhibiting the growth of causative bacteria. This prescription medication requires adherence to your doctor's instructions, ideally taken on an empty stomach at the same time daily for optimal results. Exceeding the prescribed dosage can be harmful. Missed doses should be taken promptly upon recollection. Complete the full course of treatment, even with symptom improvement; premature cessation can reduce effectiveness. Therapeutic effects may take time to manifest. Consult your physician if symptoms worsen or fail to improve. Common side effects include nausea, vomiting, fever, darkened urine, sweating, increased salivation, etc. Hydration is crucial to manage these. Report any worsening side effects immediately. Although rare, serious adverse reactions are possible. Seek immediate medical attention for allergic reactions (rashes, itching, swelling, difficulty breathing). Inform your doctor about all current medications. Individuals with liver or kidney disease should exercise caution and seek medical advice before use. Pregnant or breastfeeding women must consult their doctor. Alcohol consumption should be avoided due to potential increased drowsiness. While generally non-impairing, driving should be avoided if drowsiness or dizziness occurs. Adequate rest and a nutritious diet are recommended for faster recovery. Your doctor may order blood tests and other diagnostic procedures to monitor treatment progress.

Uses of Isorif 450mg/300mg Tablet

Managing Tuberculosis (TB) Infection

Major Benefits of Isorif 450mg/300mg Tablet:

Consume this medication precisely as prescribed by your physician, adhering to both the dosage and treatment length. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. The Isorif 450mg/300mg Tablet should be taken on an empty stomach. Refrain from consuming tyramine-rich foods, including cheese, cured meats, smoked fish, and certain beers, while taking Isorif 450mg/300mg Tablets.

Common Side effects of Isorif 450mg/300mg Tablet:

  • Dark colored urine
  • Rash
  • Vomiting
  • Jaundice
  • Fever
  • Increased liver enzymes
  • Nausea
  • Peripheral neuropathy (tingling and numbness of feet and hand)

How to use Isorif 450mg/300mg Tablet:

Administer this medication precisely as your physician directs, adhering to both the prescribed dosage and treatment period. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Consume Isorif 450mg/300mg tablets on an empty stomach. Refrain from consuming Isorif 450mg/300mg tablets concurrently with tyramine-rich foods, including cheeses, cured meats, smoked fish, and certain beers.

How Isorif 450mg/300mg Tablet works:

Isorif 450mg/300mg tablets combine rifampicin and isoniazid, two antibiotics effective against tuberculosis (TB). Rifampicin's mechanism involves disabling a crucial bacterial enzyme (RNA polymerase), halting TB bacteria protein synthesis and replication. Isoniazid concurrently disrupts the bacteria's protective cell wall formation. This dual action leads to bacterial death and disease resolution.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Ingesting alcohol concurrently with Isorif 450mg/300mg Tablet can trigger adverse effects including facial flushing, rapid heartbeat, queasiness, dehydration, pectoral pain, and hypotension (a Disulfiram-like reaction).

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Isorif 450mg/300mg tablets during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to the fetus. A physician will assess the potential advantages against any possible dangers prior to prescription. Seek medical advice.

Breast feedingBreast feedingSAFE IF PRESCRIBED

Breastfeeding mothers can generally use Isorif 450mg/300mg tablets safely. Research in humans indicates minimal drug transfer to breast milk, posing no known risk to the infant.

DrivingDrivingUNSAFE

Driving ability may be impaired by side effects of Isorif 450mg/300mg Tablets, which can include seizures, psychiatric disorders, and optic neuritis (inflammation of the optic nerve potentially resulting in vision loss).

KidneyKidneyCAUTION

Patients with kidney impairment should use Isorif 450mg/300mg Tablets cautiously, as dose modification may be necessary. Physician consultation is advised.

LiverLiverCAUTION

Patients with liver impairment should use Isorif 450mg/300mg tablets cautiously, potentially requiring dosage modification. Physician consultation is advised. Isorif 450mg/300mg tablets are contraindicated in individuals with severe hepatic dysfunction.

What if you forget to take Isorif 450mg/300mg Tablet :

Should you forget to take your Isorif 450mg/300mg Tablet, administer it immediately. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Isorif 450mg/300mg Tablet

LabelValue
Developing Habits No.
Treatment Category Antimicrobials

FAQs on Isorif 450mg/300mg Tablet

Isorif 450mg/300mg tablets combine rifampicin and isoniazid to treat tuberculosis. Rifampicin disables a crucial bacterial enzyme (RNA polymerase), halting protein synthesis and bacterial reproduction. Isoniazid prevents the tuberculosis bacteria from building a protective shell. This dual action eradicates the infection.
Follow your prescribed medication regimen precisely; do not discontinue it prematurely, even if you feel better. Refrain from alcohol consumption during treatment, as it may increase liver damage risk. Report any vision changes, appetite loss, fatigue, abdominal pain, nausea, vomiting, jaundice (yellow skin or eyes), or dark urine to your doctor immediately.
Follow your doctor's instructions precisely when taking Isorif 450mg/300mg Tablets. For best results, take the tablet on an empty stomach, either one hour before or two hours after eating.
Yes, Isorif 450mg/300mg tablets may temporarily turn your urine, skin, sweat, saliva, tears, and feces brownish-red or orange. This is harmless.
Isorif 450mg/300mg tablets can reduce the effectiveness of birth control pills. Therefore, discuss alternative, non-hormonal birth control options with your doctor, such as condoms, diaphragms, or spermicides.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication and keep it out of reach of children, pets, and others.
Isorif 450mg/300mg Tablet
44
MRP 53
16% off