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Istamet 50mg/500mg Tablet

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Prescription Required

Marketer

Sun Pharmaceutical Industries Ltd

Salt Composition

Sitagliptin (50mg) + Metformin (500mg)

Overview Istamet 50mg/500mg Tablet

Diabex Duo 50mg/500mg tablets combine two medications to manage elevated blood glucose in type 2 diabetes patients. This dual action helps mitigate serious diabetic complications like renal impairment and vision loss, potentially lowering heart attack and stroke risk. Diabex Duo may be used independently or in conjunction with other anti-diabetic therapies. Optimal results are achieved with a balanced diet and regular physical activity. Dosage is tailored to individual needs, considering current health status, glucose levels, and other medications. Consuming it with food minimizes gastrointestinal upset. Consistent daily dosing at the same time maximizes effectiveness; discontinuation requires physician approval. Adherence to the prescribed diet and exercise plan is crucial for diabetes control, as lifestyle significantly impacts management. Common side effects include nausea, diarrhea, vomiting, stomach discomfort, headache, and pharyngitis. Hypoglycemia is a potential side effect, particularly when used with insulin or sulfonylureas, necessitating awareness of its symptoms and management. This medication isn't universally suitable. Prior to use, inform your doctor of any history of kidney, liver, or heart disease, pancreatic issues, or significant alcohol consumption. Pregnant or lactating individuals require medical consultation. Interactions with other medications are possible; disclose all current medications to ensure safety. Alcohol should be limited due to its hypoglycemic effect. Your doctor will monitor kidney function and blood glucose levels throughout treatment.

Uses of Istamet 50mg/500mg Tablet

Managing type 2 diabetes

Major Benefits of Istamet 50mg/500mg Tablet:

Follow your doctor's instructions precisely regarding dosage and treatment length for this medication. Ingest the 50mg/500mg Istamet tablet whole; avoid crushing, chewing, or breaking it. Administer this medication with a meal.

Common Side effects of Istamet 50mg/500mg Tablet:

  • Decreased appetite
  • Vomiting
  • Upper respiratory tract infection
  • Hypoglycemia (low blood glucose level)
  • Abdominal bloating
  • Nausea
  • Diarrhea

How to use Istamet 50mg/500mg Tablet:

Consume this medication precisely as directed by your physician, adhering to both the prescribed dosage and treatment length. Ingest the entire tablet; do not chew, crush, or fracture it. The Istamet 50mg/500mg Tablet should be administered with a meal.

How Istamet 50mg/500mg Tablet works:

The dual-action tablet, Istamet 50mg/500mg, combines sitagliptin and metformin to manage blood glucose. Sitagliptin boosts insulin production by the pancreas, improves the body's insulin utilization, and diminishes hepatic glucose output. Metformin, a biguanide, reduces liver glucose creation, slows intestinal glucose uptake, and enhances insulin sensitivity. This synergistic action leads to superior glycemic control.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Concurrent use of alcohol and Istamet 50mg/500mg tablets poses a safety risk.

PregnancyPregnancyCONSULT YOUR DOCTOR

Use of Istamet 50mg/500mg tablets during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to a developing fetus. A physician will assess the potential benefits against possible risks prior to prescribing. Always seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Breastfeeding while taking Istamet 50mg/500mg tablets is likely inadvisable. Available human data indicates potential transfer of the medication into breast milk, posing a possible risk to the infant.

DrivingDrivingCAUTION

Impaired driving is possible with excessively low or high blood glucose levels. Refrain from driving if such symptoms arise.

KidneyKidneyCAUTION

Patients with kidney impairment should use Istamet 50mg/500mg tablets cautiously, potentially requiring dosage modification. Severe kidney disease contraindicates Istamet 50mg/500mg tablet use. Consult a physician. Regular kidney function monitoring is recommended during treatment.

LiverLiverUNSAFE

Patients with liver disease should likely avoid using Istamet 50mg/500mg tablets due to potential safety concerns. A physician's consultation is recommended.

What if you forget to take Istamet 50mg/500mg Tablet :

Should you forget to take your Istamet 50mg/500mg Tablet, administer it at your earliest convenience. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Istamet 50mg/500mg Tablet

LabelValue
Developing Habits No.
Type of Therapy Diabetes Management

FAQs on Istamet 50mg/500mg Tablet

Istamet 50mg/500mg tablets combine sitagliptin and metformin to treat type 2 diabetes in adults. This combination improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin increases insulin release by inhibiting DPP-4. It's not suitable for individuals under 18.
Prolonged Istamet 50mg/500mg Tablet use can lead to vitamin B12 deficiency by hindering its absorption. This deficiency, if left untreated, may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, and balance problems), urinary issues, and cognitive changes. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Istamet 50mg/500mg tablets may cause common side effects such as hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use can also result in vitamin B12 deficiency.
Patients with known allergies to Istamet 50mg/500mg Tablet components or excipients, or those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis should not use this medication.
Combining alcohol and Istamet 50mg/500mg tablets is unsafe and may heighten the risk of lactic acidosis.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication and keep it out of reach of children, pets, and others.
Lactic acidosis, a serious medical emergency (also known as MALA, or Metformin-associated lactic acidosis), is a possible side effect of Istamet 50mg/500mg Tablet. This is due to a buildup of lactic acid in the blood and is rare, but avoided in patients with kidney disease, the elderly, or those who consume excessive alcohol. Symptoms can include muscle pain or weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If you experience these, discontinue Istamet and seek immediate medical attention.
Istamet 50mg/500mg tablets combine sitagliptin and metformin to treat type 2 diabetes in adults. This combination improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin increases insulin release by inhibiting DPP-4. It's not suitable for individuals under 18.
Istamet 50mg/500mg Tablets may cause common side effects such as hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory tract infections. Rare but serious side effects include lactic acidosis. Prolonged use may result in vitamin B12 deficiency.
Patients with known allergies to Istamet 50mg/500mg Tablet components or excipients, or those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis should not use this medication.
Combining alcohol and Istamet 50mg/500mg tablets is unsafe due to the increased risk of lactic acidosis.
Lactic acidosis, a serious medical emergency (also known as MALA, or Metformin-associated lactic acidosis), is a potential side effect of Istamet 50mg/500mg tablets. This condition, caused by excessive blood lactic acid, is rare but warrants caution, especially for older adults, those with kidney problems, or heavy alcohol consumers. Symptoms can include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If you experience any of these, discontinue Istamet and seek immediate medical attention.
Prolonged Istamet 50mg/500mg Tablet use can lead to vitamin B12 deficiency by hindering its absorption. This deficiency may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, urinary issues, cognitive changes, and ataxia), if left unaddressed. Preventive measures may include annual supplemental vitamin B12 intake.
Store this medication in its original, tightly closed container, as directed on the label. Discard any unused medication and keep it out of reach of children, pets, and others.
Istamet 50mg/500mg tablets combine sitagliptin and metformin to treat type 2 diabetes in adults. This combination improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin increases insulin release by inhibiting DPP-4. It's not suitable for individuals under 18.
Istamet 50mg/500mg tablets may cause common side effects such as hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use may also result in vitamin B12 deficiency.
Patients allergic to Istamet 50mg/500mg Tablet components or excipients, or with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis should not use this medication.
Combining alcohol and Istamet 50mg/500mg tablets is unsafe and may heighten the risk of lactic acidosis.
Lactic acidosis, a serious medical emergency characterized by excessive blood lactic acid (also known as Metformin-associated lactic acidosis or MALA), is a potential side effect of Istamet 50mg/500mg Tablet. This rare complication is more likely in patients with kidney disease, older adults, or those who consume large amounts of alcohol, and should be avoided in these populations. Symptoms include muscle pain or weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If these symptoms occur, discontinue Istamet and seek immediate medical attention.
Prolonged use of Istamet 50mg/500mg tablets can lead to vitamin B12 deficiency by hindering its absorption. This deficiency may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, and balance problems), urinary issues, and cognitive changes. To mitigate these risks, annual supplemental vitamin B12 is recommended by some researchers.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication and ensure it's inaccessible to children, pets, and others.
Istamet 50mg/500mg Tablet
134
MRP 156
14% off