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Istamet XR 500 Tablet

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Prescription Required

Marketer

Sun Pharmaceutical Industries Ltd

Salt Composition

Sitagliptin (100mg) + Metformin (500mg)

Overview Istamet XR 500 Tablet

Diabex Duo 500mg extended-release tablets combine two medications to manage elevated blood glucose in type 2 diabetes patients. This dual action helps prevent serious diabetic complications like vision loss and kidney disease, potentially lowering heart attack and stroke risk. Diabex Duo 500mg may be used alone or in conjunction with other diabetes treatments. Optimal results are achieved with a balanced diet and regular physical activity. Dosage is personalized based on your health, blood sugar readings, and current medications. Taking it with food minimizes stomach upset. Consistent daily dosing at the same time maximizes effectiveness; discontinuation should only occur under medical supervision. Adherence to your doctor's dietary and exercise plan is crucial for effective diabetes management; lifestyle significantly impacts control. Common side effects include nausea, diarrhea, vomiting, stomach discomfort, headache, and sore throat. Low blood sugar (hypoglycemia) is possible, especially with insulin or sulfonylurea use; learn to recognize and treat it. This medication isn't for everyone. Inform your doctor about any pre-existing kidney, liver, or heart conditions, pancreatic issues, or excessive alcohol consumption before starting treatment. Pregnant or breastfeeding individuals should also seek medical advice. Interactions with other medications are possible; disclose all current medications to your doctor for safety. Alcohol should be limited due to its blood sugar-lowering effect. Your doctor will monitor your kidney function and blood glucose levels throughout treatment.

Uses of Istamet XR 500 Tablet

Managing type 2 diabetes

Major Benefits of Istamet XR 500 Tablet:

Follow your doctor's instructions precisely regarding the dosage and treatment length for this medication. Swallow the Istamet XR 500 Tablet whole; avoid chewing, crushing, or breaking it. Administer this medication with food.

Common Side effects of Istamet XR 500 Tablet:

  • Decreased appetite
  • Vomiting
  • Upper respiratory tract infection
  • Hypoglycemia (low blood glucose level)
  • Abdominal bloating
  • Nausea
  • Diarrhea

How to use Istamet XR 500 Tablet:

Consume this medication according to your physician's prescribed dosage and schedule. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Administer Istamet XR 500 Tablet with a meal.

How Istamet XR 500 Tablet works:

Istamet XR 500 Tablets contain sitagliptin and metformin, working synergistically to manage blood glucose. Sitagliptin enhances insulin production by the pancreas, improves insulin utilization, and decreases hepatic glucose output. Metformin, a biguanide, reduces liver glucose production, slows intestinal glucose absorption, and enhances insulin sensitivity. This dual action leads to improved glycemic control.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Consuming alcohol alongside Istamet XR 500 Tablet is inadvisable.

PregnancyPregnancyCONSULT YOUR DOCTOR

Extended-release Isometheptene 500 mg tablets may pose risks during pregnancy. While human data is scarce, animal research indicates potential harm to the fetus. A physician will assess the advantages against possible hazards prior to prescribing. Seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Use of Istamet XR 500 Tablet while breastfeeding is likely inadvisable. Available human data indicate potential transfer of the medication into breast milk, posing a possible risk to the infant.

DrivingDrivingCAUTION

Driving ability can be impaired by both hypoglycemia and hyperglycemia. Refrain from driving if you experience these conditions.

KidneyKidneyCAUTION

Patients with kidney impairment should use Istamet XR 500 Tablets cautiously, potentially requiring dosage modification. Severe kidney disease contraindicates Istamet XR 500 Tablet use. Regular kidney function monitoring is recommended during treatment. Physician consultation is advised.

LiverLiverUNSAFE

Patients with liver conditions should likely avoid Istamet XR 500 Tablets due to potential safety concerns. Medical advice is recommended.

What if you forget to take Istamet XR 500 Tablet :

Should you forget to take your Istamet XR 500 Tablet, ingest it immediately upon remembrance. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Istamet XR 500 Tablet

LabelValue
Developing Habits No.
Type of Treatment Diabetes Management

FAQs on Istamet XR 500 Tablet

Istamet XR 500 Tablet combines sitagliptin and metformin to manage type 2 diabetes in adults. This combination improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin increases insulin release by inhibiting DPP-4. It's not suitable for individuals under 18.
Prolonged Istamet XR 500 Tablet use can lead to vitamin B12 deficiency by hindering its absorption. This deficiency may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, and balance problems), urinary issues, and cognitive changes. To mitigate these risks, annual supplemental vitamin B12 is recommended by some researchers.
Istamet XR 500 Tablet may cause common side effects such as hypoglycemia, taste changes, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use can also result in vitamin B12 deficiency.
Istamet XR 500 Tablets are contraindicated in patients with known allergies to any ingredient or excipient. This medication should also be avoided in patients with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Istamet XR 500 Tablet and alcohol is unsafe due to the increased risk of lactic acidosis.
Store this medication in its original, tightly closed container, as directed on the label or packaging. Discard any unused medication and keep it out of reach of children, pets, and others.
Metformin, including Istamet XR 500 Tablet, can cause lactic acidosis, a serious medical emergency characterized by excessive blood lactic acid (also known as MALA). This rare side effect is more likely in patients with kidney disease, older adults, or those who consume large amounts of alcohol. Symptoms may include muscle pain or weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If you experience these, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Istamet XR 500 Tablet combines sitagliptin and metformin to treat type 2 diabetes mellitus in adults. This combination improves blood glucose control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin increases insulin release by inhibiting DPP-4. It's not suitable for individuals under 18.
Istamet XR 500 Tablet may cause common side effects such as hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory tract infections. Rare but serious side effects include lactic acidosis. Prolonged use may also result in vitamin B12 deficiency.
Istamet XR 500 Tablets are contraindicated in patients with known allergies to any ingredient or excipient. Avoid use in patients with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Istamet XR 500 Tablet with alcohol is unsafe and may raise your risk of lactic acidosis.
Lactic acidosis, a serious medical emergency (also known as MALA, or Metformin-associated lactic acidosis), is a potential side effect of Istamet XR 500 Tablet. This occurs due to excessive lactic acid buildup in the blood. Because it's rare, metformin is avoided in patients with kidney disease, the elderly, and heavy alcohol users. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If you experience these, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Prolonged Istamet XR 500 Tablet use can lead to vitamin B12 deficiency by hindering its absorption. This deficiency, if left untreated, may cause anemia, nerve damage (manifesting as numbness, tingling in extremities, weakness, and balance problems), urinary issues, and cognitive changes. To mitigate these risks, supplemental vitamin B12 is recommended at least annually by some researchers.
Store this medication in its original, tightly closed container, following the storage instructions on the label or packaging. Discard any unused medication and keep it out of reach of children, pets, and others.
Istamet XR 500 Tablet combines sitagliptin and metformin to manage type 2 diabetes in adults. This combination improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin increases insulin release by inhibiting DPP-4. It's not suitable for individuals under 18.
Istamet XR 500 Tablet may cause common side effects including hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory tract infections. Rare but serious side effects such as lactic acidosis may occur. Prolonged use can also result in vitamin B12 deficiency.
Patients with known allergies to Istamet XR 500 Tablet components or excipients, or those experiencing severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis, should not use this medication.
Combining Istamet XR 500 Tablet with alcohol is unsafe and may raise your risk of lactic acidosis.
Metformin, such as in Istamet XR 500 Tablet, can rarely cause lactic acidosis (MALA), a serious medical emergency resulting from excessive blood lactic acid. This risk is higher in patients with kidney disease, older adults, and heavy alcohol users, hence metformin is avoided in these groups. Symptoms include muscle pain or weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If you experience these, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Prolonged use of Istamet XR 500 Tablets can lead to vitamin B12 deficiency by hindering its absorption. This deficiency, if left untreated, may cause anemia, neurological issues like numbness and tingling in the extremities, weakness, urinary problems, cognitive changes, and balance difficulties (ataxia). To mitigate this risk, supplemental vitamin B12 is recommended annually by some researchers.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication and ensure it's inaccessible to children, pets, and others.
Istamet XR 500 Tablet
124
MRP 144
13% off