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Istamet XR 500 Tablet

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Prescription Required

Marketer

Sun Pharmaceutical Industries Ltd

Salt Composition

Sitagliptin (100mg) + Metformin (500mg)

Overview Istamet XR 500 Tablet

Diabetam XR 500mg combines two agents to manage elevated blood glucose in type 2 diabetes patients. This dual action mitigates severe diabetic complications like nephropathy and vision impairment, potentially lowering cardiovascular event risk. Diabetam XR 500mg might be used alone or with other antidiabetic therapies; optimal results require adherence to a balanced diet and regular physical activity. Dosage is individualized based on your health status, glycemic control, and concomitant medications. Consuming it with food minimizes gastrointestinal discomfort. Consistent daily dosing at the same time maximizes efficacy; discontinuation should only occur under physician guidance. Continued adherence to your prescribed diet and exercise regimen is crucial for successful diabetes management; lifestyle factors significantly influence glycemic control. Common side effects include nausea, diarrhea, vomiting, dyspepsia, headache, and pharyngitis. Hypoglycemia is possible, especially when combined with insulin or sulfonylureas; learn to identify and manage this complication. This medication isn't universally appropriate. Inform your physician of any pre-existing kidney, liver, or heart conditions, pancreatic issues, or significant alcohol consumption before starting. Pregnant or lactating individuals should seek medical counsel prior to use. Interactions with other medications are possible; disclose all medications to your doctor to ensure safety. Alcohol should be limited due to its hypoglycemic effect. Your doctor will monitor kidney function and blood glucose levels throughout treatment.

Primary Ingredients of Istamet XR 500 Tablet

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Uses of Istamet XR 500 Tablet

Managing type 2 diabetes

Major Benefits of Istamet XR 500 Tablet:

Follow your doctor's instructions or the package insert for proper administration. Take one Istamet XR 500 Tablet with a meal.

Common Side effects of Istamet XR 500 Tablet:

  • Decreased appetite
  • Vomiting
  • Upper respiratory tract infection
  • Hypoglycemia (low blood glucose level)
  • Abdominal bloating
  • Nausea
  • Diarrhea

How to use Istamet XR 500 Tablet:

Follow your doctor's instructions or consult the product label for usage guidelines. Always take Istamet XR 500 Tablets with a meal.

How Istamet XR 500 Tablet works:

Invokana XR 500mg combines sitagliptin and metformin to manage blood glucose. Sitagliptin boosts insulin production, improves insulin utilization, and lessens hepatic glucose output. Metformin, a biguanide, reduces liver glucose production, slows intestinal glucose absorption, and enhances insulin sensitivity. This dual action leads to improved glycemic control.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Combining Istamet XR 500 Tablets with alcohol is inadvisable.

PregnancyPregnancyCONSULT YOUR DOCTOR

Prolonged-release Istamet 500 mg tablets may pose risks during pregnancy. While human data is scarce, animal research indicates potential harm to a fetus. A physician will assess the potential advantages against any possible dangers prior to prescribing. Seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Use of Istamet XR 500 tablets while breastfeeding is likely inadvisable. Available human data indicates potential transfer to breast milk, posing a possible risk to the infant.

DrivingDrivingCAUTION

Driving ability can be impaired by both hypoglycemia and hyperglycemia. Refrain from driving if you experience these conditions.

KidneyKidneyCAUTION

Patients with kidney impairment should use Istamet XR 500mg tablets cautiously, potentially requiring dosage modification. Severe kidney disease contraindicates the use of Istamet XR 500mg tablets. Physician consultation is recommended. Regular kidney function monitoring is advised during treatment.

LiverLiverUNSAFE

Patients with liver impairment should likely avoid Istamet XR 500 mg tablets, as their use may be unsafe. Medical advice is recommended.

What if you forget to take Istamet XR 500 Tablet :

Should you forget a dose of Istamet XR 500 Tablet, take it immediately. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual regimen. Avoid taking a double dose.

Facts to Know About Istamet XR 500 Tablet

LabelValue
Developing Habits No.
Treatment Category Diabetes Management

FAQs on Istamet XR 500 Tablet

Istamet XR 500 Tablet combines sitagliptin and metformin to treat type 2 diabetes mellitus in adults. It improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin increases insulin release by inhibiting DPP-4. This combination is not for use in individuals under 18.
Prolonged Istamet XR 500 Tablet use can lead to vitamin B12 deficiency by hindering its absorption. This deficiency, if left untreated, may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, and balance problems), urinary issues, and cognitive changes. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Istamet XR 500 Tablet may cause common side effects such as hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infection. Rare but serious side effects include lactic acidosis. Prolonged use may result in vitamin B12 deficiency.
Istamet XR 500 Tablet is contraindicated in patients with hypersensitivity to its components or excipients, and those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining alcohol and Istamet XR 500 Tablets is unsafe and may heighten the risk of lactic acidosis.
Store this medication in its original, tightly closed container, following the storage instructions on the label or packaging. Discard any unused medication and ensure it's inaccessible to children, pets, and others.
Lactic acidosis, a serious medical emergency (also known as MALA, or Metformin-associated lactic acidosis), is a potential side effect of Istamet XR 500 Tablet (containing metformin). This rare complication arises from excessive blood lactic acid and is more likely in patients with kidney disease, older adults, or those who consume large amounts of alcohol. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If these occur, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Istamet XR 500 Tablet combines sitagliptin and metformin to treat type 2 diabetes in adults. It helps control blood sugar when used with diet and exercise. Metformin reduces liver glucose production and improves insulin sensitivity, while sitagliptin boosts insulin release by inhibiting DPP-4. This medication is not suitable for individuals under 18.
Istamet XR 500 Tablet may cause common side effects such as low blood sugar (hypoglycemia), altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use may also result in vitamin B12 deficiency.
Istamet XR 500 Tablet is contraindicated in patients with known allergies to its components or excipients, and in those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Istamet XR 500 Tablet and alcohol is unsafe and may raise your risk of lactic acidosis.
Lactic acidosis, a serious medical emergency (also known as MALA, or Metformin-associated lactic acidosis), is a potential side effect of Istamet XR 500 Tablet (containing metformin). This rare complication, more likely in patients with kidney disease, advanced age, or high alcohol consumption, is characterized by elevated blood lactic acid levels. Symptoms can include muscle pain or weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If you experience these symptoms, discontinue Sitagliptin + Metformin immediately and seek medical attention.
Prolonged use of Istamet XR 500 Tablets can lead to vitamin B12 deficiency by hindering its absorption. This deficiency may cause anemia and neurological issues, including numbness and tingling in the extremities, weakness, urinary difficulties, cognitive changes, and balance problems (ataxia). To mitigate these risks, annual supplemental vitamin B12 is recommended by some researchers.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication and keep it out of reach of children, pets, and others.
Istamet XR 500 Tablet combines sitagliptin and metformin to manage type 2 diabetes in adults. It enhances blood glucose control when used with diet and exercise. Metformin reduces liver glucose production and improves insulin sensitivity, while sitagliptin boosts insulin release by inhibiting DPP-4. This medication is not suitable for individuals under 18.
Istamet XR 500 Tablet may cause common side effects such as hypoglycemia (low blood sugar), altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use can also result in vitamin B12 deficiency.
Istamet XR 500 Tablets are contraindicated in patients with known allergies to any ingredient. Avoid use in patients with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Istamet XR 500 Tablet and alcohol is unsafe and may heighten the risk of lactic acidosis.
Lactic acidosis, a serious medical emergency (also known as MALA, or Metformin-associated lactic acidosis), is a potential side effect of Istamet XR 500 Tablet (containing metformin). This rare complication is characterized by elevated blood lactic acid levels and is more likely in patients with kidney disease, older individuals, or those who consume excessive alcohol. Symptoms can include muscle pain or weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If you experience these symptoms, discontinue Sitagliptin + Metformin immediately and seek immediate medical attention.
Prolonged use of Istamet XR 500 Tablets can lead to vitamin B12 deficiency by hindering its absorption in the stomach. This deficiency may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, urinary issues, cognitive changes, and ataxia), if left unaddressed. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Store this medication in its original, tightly closed container, following the storage instructions on the packaging. Discard any unused medication and ensure it's inaccessible to children, pets, and others.
Istamet XR 500 Tablet
124
MRP 144
13% off