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Leevarin 50 Injection

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Prescription Required

Marketer

Admac Pharma Ltd

Salt Composition

Calcium Leucovorin (10mg/ml)

Overview Leevarin 50 Injection

Leucovorin 50 mg Injection counteracts the adverse effects of methotrexate, a chemotherapy drug. It also serves as an antidote for methotrexate overdoses. Administered intravenously at a slow rate under medical supervision, the dosage and frequency are determined by your physician based on your specific condition and may be adjusted. Strict adherence to your doctor's instructions is crucial; improper usage or excessive dosage can lead to severe complications. Injection site reactions, including pain, swelling, and redness, are common. Report any bothersome or severe reactions to your physician; management strategies exist to mitigate these effects. Regular blood tests monitor blood cell counts and serum methotrexate levels. Prior to treatment, disclose any history of seizures, liver or kidney disease, or current use of infection-fighting medications. Inform your healthcare provider about all medications you are taking, especially anticonvulsants like phenytoin, as drug interactions are possible. If pregnant or breastfeeding, consult your doctor to ensure the safety of Leucovorin 50 mg Injection.

Primary Ingredients of Leevarin 50 Injection

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Uses of Leevarin 50 Injection

Mitigating Methotrexate's Adverse Reactions

Major Benefits of Leevarin 50 Injection:

This medication will be administered by your physician or registered nurse; self-medication is strictly prohibited.

Common Side effects of Leevarin 50 Injection:

  • Injection site reactions (pain, swelling, redness)

How to use Leevarin 50 Injection:

This medication will be administered by your healthcare provider. Self-medication is strictly prohibited.

How Leevarin 50 Injection works:

Leevarin 50 Injection, a vitamin B derivative, safeguards healthy cells from methotrexate's toxicity, enabling the anticancer drug to selectively target and eliminate cancerous cells.

SAFETY ADVICE

AlcoholAlcoholCONSULT YOUR DOCTOR

Alcohol consumption alongside Leevarin 50 Injection may be unsafe; seek medical advice before combining them.

PregnancyPregnancyCONSULT YOUR DOCTOR

Administering Leevarin 50 Injection during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to the fetus. A physician will assess the advantages against possible hazards prior to prescribing. Seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Data on Leevarin 50 Injection use while breastfeeding is lacking. Seek medical advice from your physician.

DrivingDrivingSAFE

Driving ability is typically unaffected by Leevarin 50 Injection.

KidneyKidneyCONSULT YOUR DOCTOR

Data regarding Leevarin 50 Injection's use in patients exhibiting renal impairment is scarce. Physician consultation is advised.

LiverLiverCONSULT YOUR DOCTOR

Data regarding Leevarin 50 Injection use in individuals with hepatic impairment is scarce. Physician consultation is advised.

What if you forget to take Leevarin 50 Injection :

Should you forget a Leevarin 50 Injection, administer it at your earliest convenience. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Leevarin 50 Injection

LabelValue
Chemical Category Glutamate Derivatives
Developing Habits No.
Type of Therapy KINSHIP
Actions Methotrexate as a cytoprotective agent

FAQs on Leevarin 50 Injection

Leevarin 50 Injection counteracts methotrexate's harmful side effects during cancer treatment. It also treats methotrexate overdose and similar medication overdoses. Furthermore, it addresses megaloblastic anemia resulting from folic acid deficiency where oral medication is unsuitable.
Anemia is a condition where insufficient oxygen-carrying red blood cells reduce oxygen delivery to tissues and organs. Megaloblastic anemia, a type of anemia, features abnormally large, yet fewer, red blood cells, typically caused by vitamin B12 or folic acid deficiency. How quickly does Leevarin 50 Injection take effect?
Leevarin 50 Injection typically begins working within five minutes, although the onset of action can vary depending on factors such as dosage and individual patient response.
To determine the appropriate Leevarin 50 Injection dosage and treatment length, your doctor will order blood tests. These will include serum methotrexate levels (if you're receiving methotrexate chemotherapy or have overdosed) and a complete blood count to monitor red blood cell levels (especially if megaloblastic anemia is a concern). Calcium level monitoring will also be done to prevent hypercalcemia, as Leevarin 50 Injection contains calcium.
Maintain adult urine output above 2500 mL daily by increasing oral or intravenous fluids for 48 hours, starting 12 hours prior to methotrexate infusion. Ensure urinary pH remains above 7.0 before, and throughout, methotrexate administration by avoiding acidic foods, drinks, and medications. Monitor blood methotrexate levels at 24, 48, and 72 hours post-infusion.
Leevarin 50 Injection
258
MRP 299
13% off