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Lupisit M 100mg/1000mg Tablet XR

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Prescription Required

Marketer

Lupin Ltd

Salt Composition

Sitagliptin (100mg) + Metformin (1000mg)

Overview Lupisit M 100mg/1000mg Tablet XR

Diabex Duo 100mg/1000mg Extended-Release Tablets combine two active ingredients to manage elevated blood glucose in adults with type 2 diabetes. This dual action helps prevent serious diabetic complications like nephropathy and retinopathy, and may lessen the risk of cardiovascular events. Diabex Duo may be used as monotherapy or in conjunction with other antidiabetic agents. Optimal results are achieved with a balanced diet and regular physical activity. Dosage is individualized, factoring in your health status, blood glucose readings, and other medications. Consuming the tablets with food can minimize gastrointestinal discomfort. Consistent daily dosing at the same time maximizes therapeutic benefit; discontinuation should only occur under medical supervision. Adherence to your prescribed diet and exercise plan is crucial for successful diabetes management. Commonly reported side effects include nausea, vomiting, diarrhea, abdominal discomfort, headache, and pharyngitis. Hypoglycemia is a potential adverse effect, especially when combined with insulin or sulfonylureas; proper recognition and management of this condition are essential. This medication isn't suitable for all patients. Consult your physician prior to use if you have a history of renal, hepatic, or cardiac disease, pancreatic disorders, or significant alcohol consumption. Pregnant or lactating individuals should seek medical advice before initiating treatment. Drug interactions are possible; inform your doctor of all current medications to ensure safe usage. Alcohol should be limited due to its potential to exacerbate hypoglycemia. Your doctor will monitor renal function and blood glucose throughout your treatment.

Uses of Lupisit M 100mg/1000mg Tablet XR

Managing type 2 diabetes

Major Benefits of Lupisit M 100mg/1000mg Tablet XR:

Consume this medication precisely as prescribed by your physician, adhering to both the dosage and treatment length. Ingest the Lupisit M 100mg/1000mg Extended-Release tablet whole; avoid chewing, crushing, or fracturing it. Administration should coincide with a meal.

Common Side effects of Lupisit M 100mg/1000mg Tablet XR:

  • Decreased appetite
  • Vomiting
  • Upper respiratory tract infection
  • Hypoglycemia (low blood glucose level)
  • Abdominal bloating
  • Nausea
  • Diarrhea

How to use Lupisit M 100mg/1000mg Tablet XR:

Follow your doctor's instructions precisely regarding dosage and treatment length for this medication. Ingest the Lupisit M 100mg/1000mg Extended-Release tablet whole; avoid chewing, crushing, or breaking it. Administer this medication with food.

How Lupisit M 100mg/1000mg Tablet XR works:

Lupisit M XR, a 100mg/1000mg tablet, combines sitagliptin and metformin to manage blood glucose. Sitagliptin enhances insulin production by the pancreas, improves insulin utilization, and reduces hepatic glucose output. Metformin, a biguanide, decreases liver glucose production, slows intestinal glucose absorption, and increases insulin sensitivity. This dual action leads to superior glycemic control.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Concurrent use of alcohol and Lupisit M 100mg/1000mg XR tablets is inadvisable.

PregnancyPregnancyCONSULT YOUR DOCTOR

Extended-release Lupisit M 100mg/1000mg tablets might pose risks during pregnancy. While human data is scarce, animal research indicates potential harm to a developing fetus. A physician will assess the advantages against possible hazards prior to prescription. Seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Extended-release Lupisit M 100mg/1000mg tablets are likely unsafe for breastfeeding mothers. Available human data indicate potential transfer to breast milk, posing a risk to the infant.

DrivingDrivingCAUTION

Driving ability can be impaired by both hypoglycemia and hyperglycemia. Refrain from driving if you experience these conditions.

KidneyKidneyCAUTION

Patients with kidney impairment should use Lupisit M 100mg/1000mg Extended-Release Tablets cautiously, potentially requiring dosage modification. Severe kidney disease contraindicates the use of Lupisit M 100mg/1000mg Extended-Release Tablets. Physician consultation is recommended. Regular monitoring of renal function is advised during treatment.

LiverLiverUNSAFE

Extended-release Lupisit M 100mg/1000mg tablets are likely unsuitable for individuals with hepatic impairment and should be avoided. Medical advice is recommended.

What if you forget to take Lupisit M 100mg/1000mg Tablet XR :

Should you forget a Lupisit M 100mg/1000mg Tablet XR dose, ingest it immediately. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Lupisit M 100mg/1000mg Tablet XR

LabelValue
Developing Habits No.
Treatment Category Diabetes Management

FAQs on Lupisit M 100mg/1000mg Tablet XR

Lupisit M 100mg/1000mg XR tablets combine sitagliptin and metformin to manage type 2 diabetes in adults. This medication improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin boosts insulin release by inhibiting DPP-4. This combination is unsuitable for individuals under 18.
Prolonged use of Lupisit M 100mg/1000mg Tablet XR can lead to vitamin B12 deficiency by impairing its absorption. This deficiency, if left untreated, may cause anemia, neurological issues such as tingling, numbness in extremities, weakness, urinary problems, cognitive changes, and ataxia. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Lupisit M 100mg/1000mg Tablet XR may cause common side effects such as hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use can also result in vitamin B12 deficiency.
Lupisit M 100mg/1000mg Tablet XR is contraindicated in patients with known allergies to its components or excipients, and in those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Lupisit M 100mg/1000mg Tablet XR and alcohol is unsafe due to the increased risk of lactic acidosis.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication and keep it out of reach of children, pets, and others.
Metformin, such as in Lupisit M 100mg/1000mg XR, can cause lactic acidosis (MALA), a serious medical condition involving high blood lactic acid levels. This rare side effect is more likely in patients with kidney disease, older adults, or those who consume excessive alcohol. Symptoms include muscle pain or weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and slowed heart rate. If you experience these, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Lupisit M 100mg/1000mg XR tablets combine sitagliptin and metformin to manage type 2 diabetes in adults. This combination improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin increases insulin release by inhibiting DPP-4. This medication is not suitable for individuals under 18.
Lupisit M 100mg/1000mg Tablet XR may cause common side effects such as hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory tract infections. Rare but serious side effects include lactic acidosis. Prolonged use can also result in vitamin B12 deficiency.
Lupisit M 100mg/1000mg Tablet XR is contraindicated in patients with known allergies to its components or excipients, and in those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Lupisit M 100mg/1000mg Tablet XR with alcohol is unsafe and may heighten the risk of lactic acidosis.
Metformin, a component of Lupisit M 100mg/1000mg Tablet XR, can cause lactic acidosis (MALA – Metformin-associated lactic acidosis), a serious medical emergency resulting from excessive blood lactic acid. This rare side effect necessitates avoiding metformin in patients with kidney disease, the elderly, or those who consume excessive alcohol. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If these occur, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Prolonged use of Lupisit M 100mg/1000mg Tablet XR can lead to vitamin B12 deficiency by hindering its absorption. This deficiency may cause anemia, neurological issues (including tingling, numbness in extremities, weakness, and ataxia), and urinary problems, potentially affecting mental state. To mitigate these risks, annual supplemental vitamin B12 is recommended by some researchers.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication; keep it out of reach of children, pets, and others.
Lupisit M 100mg/1000mg XR tablets combine sitagliptin and metformin to treat type 2 diabetes in adults. This combination improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin increases insulin release by inhibiting DPP-4. This medication is not suitable for individuals under 18 years of age.
Lupisit M 100mg/1000mg Tablet XR may cause common side effects such as hypoglycemia, taste changes, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use can also result in vitamin B12 deficiency.
Lupisit M 100mg/1000mg Tablet XR is contraindicated in patients with allergies to its components or excipients, and those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Lupisit M 100mg/1000mg Tablet XR with alcohol is unsafe and may heighten the risk of lactic acidosis.
Lactic acidosis, a serious medical emergency (also known as MALA, or Metformin-associated lactic acidosis), is a potential side effect of Lupisit M 100mg/1000mg Tablet XR. This occurs due to excessive blood lactic acid. Because it's rare, metformin is avoided in patients with kidney disease, the elderly, or those who consume significant alcohol. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and slow heart rate. If experienced, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Prolonged use of Lupisit M 100mg/1000mg Tablet XR can lead to vitamin B12 deficiency by impairing its absorption. This deficiency may cause anemia, nerve damage (manifested as tingling, numbness in extremities, weakness, urinary issues, cognitive changes, and ataxia), if left unaddressed. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Store this medication in its original, tightly closed container, following the storage instructions on the label or packaging. Discard any unused medication and ensure it's inaccessible to children, pets, and others.
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