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Matibenz 400 Tablet

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Prescription Required

Marketer

Admac Pharma Ltd

Salt Composition

Imatinib mesylate (400mg)

Overview Matibenz 400 Tablet

Imatinib 400mg tablets are indicated for various cancers. Primarily, they treat hematologic malignancies such as chronic myeloid leukemia and acute lymphoblastic leukemia, alongside gastrointestinal stromal tumors. Its mechanism involves targeting proteins crucial to cancer cell proliferation and metastasis. This medication is also employed in dermatofibrosarcoma protuberans and aggressive systemic mastocytosis. Administer with food, consistently at the same time daily for optimal efficacy. Treatment duration is individualized based on response and need; adherence to the prescribed regimen is vital. Incorrect usage or overdose can result in severe adverse effects. While benefits may take weeks or months to manifest, discontinuation should only occur under physician guidance. Common side effects include swelling, nausea, vomiting, muscle spasms, musculoskeletal discomfort, diarrhea, skin rashes, tiredness, and stomach pain. Report unexplained rapid weight increase immediately. Regular blood count and liver function monitoring may be recommended. Avoid activities requiring alertness if dizziness or blurred vision arise. Inform your healthcare provider of all other medications as interactions are possible. This medication is contraindicated during pregnancy and lactation; effective contraception for both partners is essential throughout treatment.

Uses of Matibenz 400 Tablet

Oncological Management

Major Benefits of Matibenz 400 Tablet:

Consume this medication precisely as prescribed by your physician, adhering to the specified dosage and treatment period. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. It is recommended to take Matibenz 400 Tablet with a meal.

Common Side effects of Matibenz 400 Tablet:

  • Edema (swelling)
  • Nausea
  • Vomiting
  • Muscle cramp
  • Musculoskeletal (bone, muscle or joint) pain
  • Diarrhea
  • Rash
  • Fatigue
  • Abdominal pain
  • Bleeding
  • Breathing problems
  • Cough
  • Weight gain
  • Dry eye
  • Dizziness
  • Hemorrhage

How to use Matibenz 400 Tablet:

Consume this medication precisely as prescribed by your physician, adhering to the advised dosage and treatment period. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Matibenz 400 Tablets should be administered with a meal.

How Matibenz 400 Tablet works:

Matibenz 400 tablets are an anticancer drug targeting the bcr-abl tyrosine kinase enzyme. This enzyme drives the uncontrolled growth of cancerous cells. By inhibiting its activity, Matibenz 400 promotes programmed cell death (apoptosis) in bcr-abl-positive cancer cells, thereby hindering or slowing cancer progression.

SAFETY ADVICE

AlcoholAlcoholCONSULT YOUR DOCTOR

The interaction of alcohol with Matibenz 400 Tablet is undetermined. Seek medical advice before combining them.

PregnancyPregnancyCONSULT YOUR DOCTOR

Using Matibenz 400 Tablets during pregnancy poses a confirmed risk to the fetus. Prescribing may occur exceptionally in life-threatening cases where benefits outweigh potential harm, at the physician's discretion. Always seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

The use of Matibenz 400 Tablets during breastfeeding is likely inadvisable. Available human data indicates potential transfer of the medication into breast milk, posing a risk to the infant. Nursing mothers should discontinue breastfeeding for the duration of Matibenz 400 Tablet use and for a further 15 days following cessation.

DrivingDrivingUNSAFE

Driving ability may be impaired by the side effects of Matibenz 400 Tablets.

KidneyKidneyCAUTION

Patients with kidney impairment should use Matibenz 400 Tablets cautiously, potentially requiring a modified dosage. Physician consultation is advised.

LiverLiverCAUTION

Patients with significant hepatic impairment should use Matibenz 400 Tablets cautiously; dosage modification may be necessary. Physician consultation is advised.

What if you forget to take Matibenz 400 Tablet :

Omit any missed Matibenz 400 Tablet dose and resume your regular medication regimen. Avoid taking a double dose.

Facts to Know About Matibenz 400 Tablet

LabelValue
Chemical Category Benzanilide Derivative
Developing Habits No.
Treatment Category Cancer Medications
Actions Kinase inhibitors targeting tyrosine

FAQs on Matibenz 400 Tablet

For optimal absorption and to minimize stomach irritation, take with food and a glass of water. If swallowing is difficult, dissolve the tablet in 50ml of water or apple juice (for 100mg tablets) or 200ml (for 400mg tablets). Stir until dissolved and consume immediately.
Taking Matibenz 400 Tablets may cause dizziness, lightheadedness, or drowsiness. Avoid driving or operating machinery until you understand how this medication affects you.
Strictly follow your doctor's instructions and attend all scheduled appointments while taking Matibenz 400 Tablets. Regular monitoring, including blood tests, weight checks, and urine tests, is necessary to detect any side effects promptly. Use contraception throughout treatment and immediately inform your doctor if pregnancy occurs. Always inform your doctor about Matibenz 400 Tablet use before starting any new medication.
This medication can significantly increase your skin's sun sensitivity, potentially leading to rash, itching, redness, or severe sunburn. Always wear protective clothing and a sunscreen with SPF 15 or higher when outdoors. Report any burning sensation to your doctor immediately.
Matibenz 400 Tablet interacts with several medications, such as paracetamol, cyclosporin, dexamethasone, warfarin, antiviral drugs (including those for AIDS), and medications for bacterial infections, high cholesterol, high blood pressure, heart conditions, mental disorders, and depression. Avoid self-medicating while taking Matibenz 400 Tablet. Always consult your doctor before starting any new medication, informing them of your Matibenz 400 Tablet treatment.
Matibenz 400 tablets have shown effectiveness in treating many chronic myeloid leukemia (CML) cases, often improving survival rates. However, your doctor should determine its suitability for you, considering your condition, blood test results, treatment response, and overall health.
Matibenz 400 Tablet
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