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Matnib 400mg Tablet

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Getwell Pharma (I) Pvt Ltd

Salt Composition

Imatinib mesylate (400mg)

Overview Matnib 400mg Tablet

Imatinib 400mg tablets are indicated for various cancers. Primarily, they treat hematologic malignancies such as chronic myeloid leukemia and acute lymphoblastic leukemia, alongside gastrointestinal stromal tumors. Their mechanism involves targeting specific proteins crucial for cancer cell proliferation and metastasis. This medication also addresses dermatofibrosarcoma protuberans (a skin tumor) and aggressive systemic mastocytosis (a bone marrow disorder). Administer this medication with food, consistently at the same time daily for optimal efficacy. Continue treatment as directed by your physician; treatment length varies based on individual response. Incorrect dosage or overdose can lead to severe adverse effects. Therapeutic benefits may take weeks or months to manifest; discontinue only under medical supervision. Common side effects encompass edema, nausea, vomiting, muscle spasms, musculoskeletal discomfort, diarrhea, skin rashes, tiredness, and stomach pain. Report sudden, significant weight gain. Regular blood count and liver function monitoring may be recommended. Avoid activities demanding alertness if dizziness or blurred vision occur. Inform your healthcare provider of all concurrent medications, as interactions are possible. This medicine is contraindicated during pregnancy and lactation; reliable contraception is crucial for both partners throughout treatment.

Primary Ingredients of Matnib 400mg Tablet

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Uses of Matnib 400mg Tablet

Oncological Management

Major Benefits of Matnib 400mg Tablet:

Consume this medication precisely as directed by your physician, adhering to the prescribed dosage and treatment period. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. It is recommended to take the 400mg Matnib tablet with a meal.

Common Side effects of Matnib 400mg Tablet:

  • Edema (swelling)
  • Nausea
  • Vomiting
  • Muscle cramp
  • Musculoskeletal (bone, muscle or joint) pain
  • Diarrhea
  • Rash
  • Fatigue
  • Abdominal pain
  • Bleeding
  • Breathing problems
  • Cough
  • Weight gain
  • Dry eye
  • Dizziness
  • Hemorrhage

How to use Matnib 400mg Tablet:

Consume this medication precisely as directed by your physician, adhering to the prescribed dosage and timeframe. Ingest the 400mg Matnib tablet whole; avoid chewing, crushing, or fracturing it. It should be taken with a meal.

How Matnib 400mg Tablet works:

Matnib 400mg tablets are used in cancer treatment. They target the bcr-abl tyrosine kinase protein, an enzyme crucial for the uncontrolled growth of specific cancer cells. By inhibiting this enzyme, Matnib prompts programmed cell death (apoptosis) in these cancerous cells, thus curbing or slowing cancer progression.

SAFETY ADVICE

AlcoholAlcoholCONSULT YOUR DOCTOR

Alcohol consumption alongside Matnib 400mg Tablet may pose unknown risks. Physician consultation is advised.

PregnancyPregnancyCONSULT YOUR DOCTOR

Use of Matnib 400mg tablets during pregnancy poses a confirmed risk to the fetus. While generally contraindicated, a physician might exceptionally prescribe it in critical circumstances where the potential advantages outweigh the known hazards. Always seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Use of Matnib 400mg tablets while breastfeeding is likely unsafe. Available human data indicates potential transfer to breast milk, posing a risk to the infant. Breastfeeding should be discontinued during Matnib treatment and for two weeks following cessation.

DrivingDrivingUNSAFE

Taking a 400mg Matnib tablet may impair driving ability due to potential adverse reactions.

KidneyKidneyCAUTION

Patients with kidney impairment should exercise caution when using Matnib 400mg tablets. Dosage modification may be necessary. Physician consultation is recommended.

LiverLiverCAUTION

Patients with severe hepatic impairment should use 400mg Matnib tablets cautiously; dosage modification may be necessary. Physician consultation is advised.

What if you forget to take Matnib 400mg Tablet :

Omit any missed 400mg Matnib Tablet dose and resume your usual medication regimen. Avoid taking a double dose.

Facts to Know About Matnib 400mg Tablet

LabelValue
Chemical Category Benzanilide Derivative
Developing Habits No.
Treatment Category Cancer Medications
Behavior Class TKIs

FAQs on Matnib 400mg Tablet

For optimal absorption and to minimize stomach irritation, take with food and a glass of water. If swallowing the tablet is difficult, dissolve it in 50ml of water or apple juice (for 100mg tablets) or 200ml (for 400mg tablets). Stir well and consume immediately.
Taking Matnib 400mg Tablets may cause dizziness, lightheadedness, or drowsiness. Avoid driving or operating machinery until you understand how this medication affects you.
Follow your doctor's instructions carefully and attend all scheduled appointments while taking Matnib 400mg tablets. Regular monitoring, including blood, urine, and weight checks, is necessary to detect side effects promptly. Use contraception throughout treatment and immediately inform your doctor if pregnancy occurs. Always tell your doctor about Matnib 400mg when starting any new medication.
This medication can increase your sun sensitivity, potentially causing rash, itching, redness, or severe sunburn. Wear protective clothing and a sunscreen with SPF 15 or higher outdoors. Report any skin burning to your doctor.
Matinib 400mg Tablet interacts with many medications, such as paracetamol, cyclosporin, dexamethasone, warfarin, antivirals (for AIDS), and drugs for bacterial infections, high cholesterol, high blood pressure, heart conditions, mental health issues, and depression. Avoid self-medicating while on Matinib 400mg Tablet. Always consult your doctor before taking any other medication and inform them you're using Matinib 400mg Tablet.
Matnib 400mg tablets have shown effectiveness in numerous CML cases, often improving survival rates. However, your doctor is best positioned to determine its suitability for you, considering your individual health status, blood test results, treatment response, and other medical conditions.
Matnib 400mg Tablet
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