Mesacol 1g Suppository
Marketer
Sun Pharmaceutical Industries Ltd
Salt Composition
Mesalazine (1gm)
Overview Mesacol 1g Suppository
Rectal administration of a 1-gram Mesacol suppository offers anti-inflammatory relief for ulcerative colitis, particularly proctitis (rectal inflammation). This medication targets bowel inflammation, alleviating symptoms like diarrhea, rectal bleeding, and abdominal pain. Administered rectally only—never orally—it requires medical supervision. Remain recumbent for at least 15 minutes post-insertion. Dosage is determined by your physician and must be followed precisely; discontinue only under their guidance, as premature cessation may exacerbate symptoms. Common side effects include rectal irritation, skin rash, pruritus, and pyrexia. Report persistent or worsening side effects to your doctor; management strategies may be available. Prior to initiating treatment, inform your doctor of any kidney or liver impairment, gastrointestinal obstructions, or pregnancy/breastfeeding status. Age may also influence treatment suitability. Always disclose all other medications you are using, as interactions are possible. Pre- and post-treatment kidney and liver function tests may be required.
Uses of Mesacol 1g Suppository
Managing ulcerative colitis
Major Benefits of Mesacol 1g Suppository:
Discard the suppository's packaging prior to administration. Remain recumbent for approximately fifteen minutes following insertion to prevent premature expulsion.
Common Side effects of Mesacol 1g Suppository:
- Rectal discomfort
- Flatulence
- Headache
- Vomiting
- Diarrhea
- Nausea
- Abdominal pain
- Rash
How to use Mesacol 1g Suppository:
Discard the suppository's packaging prior to administration. Remain recumbent for approximately 15 minutes post-insertion to prevent premature expulsion.
How Mesacol 1g Suppository works:
Rectal administration of a 1g Mesacol suppository, an aminosalicylate, delivers targeted anti-inflammatory action to the lower gastrointestinal tract (colon and rectum). This localized effect rapidly alleviates ulcerative colitis flare-ups by inhibiting the inflammatory prostaglandins responsible for ulceration, bleeding, and associated pain.
SAFETY ADVICE
AlcoholNone
No known drug interactions.
PregnancyCONSULT YOUR DOCTOR
The use of Mesacol 1g suppositories during pregnancy may pose risks. While human research is scant, animal studies indicate potential harm to the fetus. A physician will assess the potential advantages against any possible risks prior to prescribing. Physician consultation is recommended.
Breast feedingCONSULT YOUR DOCTOR
Using Mesacol 1g suppositories while breastfeeding is likely inadvisable. Available human data indicates potential transfer of the medication into breast milk, posing a risk to the infant. Mothers using Mesacol 1g suppositories should carefully observe their baby for any signs of diarrhea.
DrivingNone
No known drug interactions.
KidneyCAUTION
Individuals with impaired kidney function should use Mesacol 1g suppositories cautiously, potentially requiring dosage modification. Medical advice is necessary. Mesacol 1g suppositories are contraindicated in patients with severely compromised kidney function.
LiverCAUTION
Patients with hepatic impairment should use 1-gram Mesacol suppositories cautiously. Dosage modification may be necessary; physician consultation is advised.
What if you forget to take Mesacol 1g Suppository :
Should you forget a Mesacol 1g Suppository, administer it at your earliest convenience. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.
Facts to Know About Mesacol 1g Suppository
| Label | Value |
|---|---|
| Chemical Category | Salicylic Acid Derivative |
| Developing Habits | No. |
| Treatment Category | Gastrointestinal system |
| Actions | Mesalamine (5-ASA) |





