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Metraff-G1 Tablet SR

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Prescription Required

Marketer

Raffles Pharmaceuticals

Salt Composition

Glimepiride (1mg) + Metformin (500mg)

Overview Metraff-G1 Tablet SR

GlucoDuo SR tablets are classified as antidiabetic medications, a dual-drug formulation for managing type 2 diabetes in adults. They help regulate blood glucose. GlucoDuo SR should be ingested with food, consistently at the same time daily for optimal efficacy. Dosage is determined by your physician and may be adjusted based on blood sugar monitoring. Continue using this medication even if feeling well or experiencing controlled blood sugar; abrupt cessation, without physician consultation, risks elevated blood glucose, potentially leading to kidney complications, vision impairment, neuropathy, and limb loss. This medication is part of a comprehensive diabetes management plan encompassing a balanced diet, regular physical activity, and weight management, as directed by your doctor. Lifestyle choices significantly impact diabetes control. Hypoglycemia (low blood sugar) is a common side effect; recognize symptoms like sweating, dizziness, headache, and trembling, and have a readily available fast-acting glucose source (e.g., sugary snacks, juice). Alcohol consumption increases hypoglycemia risk and should be limited. Other potential side effects include altered taste, nausea, diarrhea, abdominal discomfort, headache, and upper respiratory infections. Weight gain may occur. This medication is contraindicated in type 1 diabetes, diabetic ketoacidosis, or severe liver/kidney disease. Inform your physician of any prior heart conditions before commencing treatment; it may be unsuitable. Pregnant or breastfeeding individuals should seek medical advice prior to use. Regular blood glucose monitoring is essential, and your doctor may order blood tests to assess blood cell counts and liver function.

Primary Ingredients of Metraff-G1 Tablet SR

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Uses of Metraff-G1 Tablet SR

Managing type 2 diabetes

Major Benefits of Metraff-G1 Tablet SR:

Follow your physician's instructions precisely regarding dosage and treatment length for this medication. Ingest the Metraff-G1 SR tablet whole; avoid chewing, crushing, or breaking it. Administer this medicine with a meal.

Common Side effects of Metraff-G1 Tablet SR:

  • Headache
  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Diarrhea

How to use Metraff-G1 Tablet SR:

Consume this medication precisely as prescribed by your physician, adhering to the specified dosage and treatment period. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. It's recommended to take Metraff-G1 Tablet SR with a meal.

How Metraff-G1 Tablet SR works:

Metformin and glimepiride, combined as Metraff-G1 SR tablets, offer a dual approach to diabetes management. Glimepiride, a sulfonylurea, stimulates pancreatic insulin secretion to reduce blood sugar. Metformin, a biguanide, acts through multiple mechanisms: decreasing hepatic glucose production, slowing intestinal glucose absorption, and enhancing insulin sensitivity.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Combining Metraff-G1 Tablet SR and alcohol is unsafe.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Metraff-G1 SR tablets during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to the unborn child. A physician will assess the potential advantages against any risks prior to prescribing. Physician consultation is advised.

Breast feedingBreast feedingUNSAFE

Sustained-release Metraff-G1 tablets are contraindicated for breastfeeding mothers. Evidence indicates potential infant toxicity from this medication.

DrivingDrivingCAUTION

Driving may be impaired by excessively low or high blood sugar levels. Refrain from driving if such symptoms arise.

KidneyKidneyCAUTION

Exercise caution when prescribing Metraff-G1 SR tablets to individuals with kidney impairment; dosage modification may be necessary. Physician consultation is recommended. Metraff-G1 SR tablets are contraindicated in patients exhibiting severe kidney dysfunction. Routine monitoring of renal function is advised during treatment.

LiverLiverCAUTION

Patients with liver impairment should use Metraff-G1 SR tablets cautiously, potentially requiring dosage modification. Consult a physician. A reduced initial dose is typically prescribed for individuals with mild to moderate liver disease; Metraff-G1 SR tablets are contraindicated in those with severe hepatic dysfunction.

What if you forget to take Metraff-G1 Tablet SR :

Should you forget a dose of Metraff-G1 SR Tablet, take it immediately if feasible. If your next dose is imminent, however, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Metraff-G1 Tablet SR

LabelValue
Developing Habits No.
Treatment Category Diabetes Management

FAQs on Metraff-G1 Tablet SR

Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication; keep it out of reach of children, pets, and others.
Metraff-G1 Tablet SR can cause lactic acidosis, a serious medical emergency characterized by high blood lactic acid levels (also known as MALA—Metformin-associated lactic acidosis). This rare but potentially harmful side effect is more likely in patients with kidney disease, older adults, or those who consume excessive alcohol. Symptoms include muscle pain or weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If you experience these, discontinue Metraff-G1 Tablet SR and seek immediate medical attention.
Metraff-G1 SR tablets combine glimepiride and metformin to manage type 2 diabetes mellitus in adults. This combination improves blood glucose control when used with diet and exercise. Glimepiride stimulates insulin release from the pancreas, while metformin reduces liver glucose production and enhances insulin sensitivity. It's not suitable for type 1 diabetes.
Metraff-G1 Tablet SR may cause common side effects such as low blood sugar (hypoglycemia), altered taste, nausea, stomach pain, diarrhea, and headache. Rare but serious side effects include lactic acidosis. Prolonged use can also result in vitamin B12 deficiency.
Prolonged Metraff-G1 Tablet SR use can lead to Vitamin B12 deficiency by interfering with its stomach absorption. This deficiency may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, and ataxia), urinary issues, and cognitive changes. To mitigate these risks, annual supplemental Vitamin B12 is recommended by some researchers.
Metraff-G1 Tablet SR can cause low blood sugar (hypoglycemia), manifesting as nausea, headache, irritability, hunger, sweating, dizziness, rapid heartbeat, anxiety, or shakiness. This risk increases with missed meals, alcohol consumption, excessive exercise, or concurrent use of other antidiabetic medications. Therefore, regular blood sugar monitoring is crucial. Always carry a fast-acting sugar source, such as glucose tablets, honey, or fruit juice.
Combining Metraff-G1 Tablet SR and alcohol is unsafe due to the risk of dangerously low blood sugar (hypoglycemia) and increased lactic acidosis.
Metraff-G1 Tablet SR
44
MRP 51
13% off