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Natfost 500mg Injection

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Prescription Required

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Natco Pharma Ltd

Salt Composition

Amifostine (500mg)

Overview Natfost 500mg Injection

Amifostine 500mg Injection combats oral dryness following head and neck radiotherapy, mitigating cisplatin chemotherapy's nephrotoxicity. Administered intravenously under medical guidance, dosage and frequency are individualized based on treatment needs and may vary. Strict adherence to prescribed instructions is vital; improper use or overdose risks severe complications. Therapeutic effects might not be immediately apparent, requiring weeks or months; discontinuation should only occur under physician direction. Common side effects include nausea, vomiting, hypotension, somnolence, vertigo, and flushing; persistent or bothersome symptoms warrant medical consultation. Adequate hydration prior to administration is recommended. Blood pressure monitoring precedes, and continues every five minutes during, intravenous infusion. Prior to treatment, disclose any cardiac conditions (e.g., arrhythmias, heart failure) or concomitant medications, particularly anti-infectives, as drug interactions are possible. Complete medication disclosure to your healthcare provider is crucial.

Uses of Natfost 500mg Injection

Managing Oral Xerostomia Following Head and Neck Cancer Radiotherapy

Major Benefits of Natfost 500mg Injection:

This medication will be administered by your healthcare provider. Self-medication is strictly prohibited.

Common Side effects of Natfost 500mg Injection:

  • Nausea
  • Vomiting
  • Decreased blood pressure
  • Hiccup
  • Sleepiness
  • Dizziness
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Fever
  • Chills

How to use Natfost 500mg Injection:

This medication will be administered by your healthcare provider. Self-medication is strongly discouraged.

How Natfost 500mg Injection works:

Natfost 500mg Injection neutralizes damaging byproducts generated by cisplatin chemotherapy or radiotherapy, thereby protecting tissue.

SAFETY ADVICE

AlcoholAlcoholCONSULT YOUR DOCTOR

Alcohol consumption alongside Natfost 500mg Injection may pose unknown risks. Seek medical advice before combining them.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Natfost 500mg Injection during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to the fetus. A physician will assess the potential advantages against any possible risks prior to prescribing. Consult your physician for advice.

Breast feedingBreast feedingSAFE IF PRESCRIBED

Administration of Natfost 500mg Injection while breastfeeding appears to pose minimal risk. Available human data indicate negligible infant hazard.

DrivingDrivingCONSULT YOUR DOCTOR

The effect of Natfost 500mg Injection on driving ability is unknown. Refrain from driving if you experience symptoms impairing concentration or reaction time.

KidneyKidneySAFE IF PRESCRIBED

Administering Natfost 500mg Injection to individuals with renal impairment is likely safe. Preliminary evidence indicates dose modification may be unnecessary; however, physician consultation is recommended.

LiverLiverCONSULT YOUR DOCTOR

Data regarding the administration of Natfost 500mg Injection to individuals with hepatic impairment is scarce. Physician consultation is advised.

What if you forget to take Natfost 500mg Injection :

NA

Facts to Know About Natfost 500mg Injection

LabelValue
Chemical Category Phosphorylated aminothiol
Developing Habits No.
Type of Therapy KINSHIP
Behavioral Class Protecting Kidney and Salivary Gland Cells

FAQs on Natfost 500mg Injection

Yes, it's FDA-approved.
Natfost 500mg Injection protects kidneys from cisplatin-induced damage in advanced ovarian cancer patients and prevents dry mouth during head and neck radiotherapy.
Natfost 500mg Injection safeguards healthy cells from chemotherapy and radiation damage. It achieves this by generating a thiol compound that neutralizes cisplatin's harmful byproducts, without hindering cisplatin's therapeutic effect.
Natfost 500mg Injection
77
MRP 93
17% off