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Neotrexate 5mg Tablet

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Glaxo SmithKline Pharmaceuticals Ltd

Salt Composition

Methotrexate (5mg)

Overview Neotrexate 5mg Tablet

Methotrexate 5mg tablets are indicated for treating various cancers, including those affecting the breast, head, neck, lungs, blood, bones, lymphatic system, and uterus. This medication also treats rheumatoid arthritis, severe, unresponsive psoriasis, and Crohn's disease. Methotrexate 5mg tablets may be administered alone or alongside other drugs, strictly as directed by your physician. Overdosage can lead to severe adverse reactions. Therapeutic benefits might not be apparent for weeks or months; discontinue use only under your doctor's instruction. Alcohol should be avoided due to the increased risk of liver injury. Common side effects include mouth sores, hair loss, low blood counts, elevated liver enzymes, nausea, and abdominal discomfort. Your physician may prescribe folic acid to mitigate some of these effects. Report any persistent or worsening side effects; management strategies exist. Methotrexate can impair immune function and potentially impact blood, liver, or kidney health. Your doctor will conduct blood tests, imaging studies, and physical examinations before and throughout treatment to monitor these aspects. Inform your doctor of pre-existing stomach, liver, or kidney issues, and any concurrent medications, particularly those combating infections, before starting treatment. Interactions with numerous other drugs are possible; disclose all medications to your healthcare provider. Methotrexate is contraindicated during pregnancy and breastfeeding due to potential harm to the fetus or infant.

Uses of Neotrexate 5mg Tablet

Cancer, rheumatoid arthritis, psoriasis, and Crohn's disease therapies.

Major Benefits of Neotrexate 5mg Tablet:

Administer this medication precisely as directed by your physician, adhering to the prescribed dosage and treatment schedule. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Neotrexate 5mg Tablets can be consumed with or without food; however, consistent daily timing is recommended.

Common Side effects of Neotrexate 5mg Tablet:

  • Ulcerative stomatitis
  • Nausea
  • Abdominal pain
  • Increased liver enzymes
  • Hair loss
  • Decreased blood cells (red cells, white cells, and platelets)

How to use Neotrexate 5mg Tablet:

Administer this medication precisely as your physician directs, adhering to both the prescribed dosage and treatment duration. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Neotrexate 5mg Tablets can be consumed with or without food, although consistent timing is recommended.

How Neotrexate 5mg Tablet works:

Methotrexate 5mg tablets exert their therapeutic effect by inhibiting dihydrofolate reductase, an enzyme crucial for cell division. This inhibition leads to anti-inflammatory activity and effectively combats cancer cells by disrupting DNA synthesis. In psoriasis, it slows skin cell proliferation and reduces inflammation. Furthermore, in rheumatoid arthritis and Crohn's disease, methotrexate 5mg tablets modulate the immune response, mitigating the self-attacking behavior that causes joint inflammation and bowel damage.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Concurrent alcohol use with Neotrexate 5mg Tablets is contraindicated.

PregnancyPregnancyUNSAFE

Use of Neotrexate 5mg tablets is strongly contraindicated during pregnancy. Pregnant women should consult their physician; research in animal and human studies reveals substantial risks to the fetus.

Breast feedingBreast feedingUNSAFE

Breastfeeding mothers should not use Neotrexate 5mg tablets. Evidence indicates potential infant toxicity from this medication.

DrivingDrivingUNSAFE

Taking a 5mg Neotrexate tablet might cause drowsiness, blurred vision, or dizziness. Refrain from driving if you experience these effects.

KidneyKidneyCAUTION

Methotrexate 5mg tablets require careful administration in individuals with impaired renal function. Dosage modification of Methotrexate 5mg tablets may be necessary. Physician consultation is recommended. Routine monitoring of kidney function is advisable during treatment.

LiverLiverCAUTION

Methotrexate 5mg tablets require careful administration in individuals with hepatic impairment. Dosage modification of Methotrexate 5mg tablets might be necessary. Physician consultation is advised.

What if you forget to take Neotrexate 5mg Tablet :

Should you forget a Neotrexate 5mg Tablet dose, administer it immediately. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Neotrexate 5mg Tablet

LabelValue
Chemical Type Glutamate Derivative
Developing Habits No.
Treatment Category Cancer Therapeutics
Actions Methotrexate: An Antimetabolite

FAQs on Neotrexate 5mg Tablet

Mouth sores and ulcers are possible side effects of Neotrexate 5mg Tablets. Folic acid may lessen these, and your doctor can discuss potential dose reduction to further alleviate the problem.
Neotrexate 5mg Tablets lower the body's folic acid levels, which is crucial for cell production. Supplementing with folic acid may alleviate some common side effects of Neotrexate 5mg Tablets, including mouth sores, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia, and liver issues.
To monitor your response to Neotrexate 5mg Tablet and detect any side effects, your doctor will require regular blood tests. These will assess your liver function and blood counts (white blood cells, red blood cells, and platelets). Further tests may be ordered based on these results.
Neotrexate 5mg Tablets can weaken your immune system, increasing the risk of serious infections, including rare but reported instances of severe lung infections. Use with extreme caution if you have an active infection.
Neotrexate 5mg Tablets can impact fertility in men and women, potentially reducing sperm count in men and causing menstrual irregularities in women. However, these effects are typically reversible upon treatment cessation.
If your husband is taking Neotrexate 5mg Tablets, avoid pregnancy. Furthermore, refrain from conceiving for at least three months after treatment completion to minimize the risk of severe birth defects.
Neotrexate 5mg Tablet
50
MRP 58
13% off