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NG 400mg/10mg Tablet

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Prescription Required

Marketer

Definer Pharmaceuticals Pvt Ltd

Salt Composition

Gabapentin (400mg) + Nortriptyline (10mg)

Overview NG 400mg/10mg Tablet

Combiflam NR 400mg/10mg tablets offer relief from neuropathic pain by interrupting pain signal transmission to the brain. Administered orally, with or without food, ideally at bedtime, consistent daily dosing ensures stable blood levels. Missed doses should be taken immediately upon recall. Complete the prescribed course, even with symptom improvement. Abrupt cessation is discouraged; consult your physician first to avoid potential symptom exacerbation. Common side effects include constipation, urinary difficulty, weight gain, fatigue, and dry mouth. Dizziness and drowsiness may occur; avoid driving or mentally demanding tasks until the medication's effects are understood. Weight gain is possible; regular exercise and a balanced diet can help mitigate this. Report any unusual mood changes, including suicidal ideation, to your doctor immediately. Prior to commencing treatment, disclose any kidney or liver conditions, and provide a complete list of current medications, as interactions can affect efficacy or mechanism. Inform your doctor if you are pregnant, intend to become pregnant, or are breastfeeding.

Primary Ingredients of NG 400mg/10mg Tablet

No text provided to rephrase.

Uses of NG 400mg/10mg Tablet

Managing neuropathic pain

Major Benefits of NG 400mg/10mg Tablet:

Administer this medication precisely as prescribed by your physician, adhering to both the dosage and treatment length. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. The NG 400mg/10mg Tablet can be consumed with or without food, although consistent timing is recommended.

Common Side effects of NG 400mg/10mg Tablet:

  • Dryness in mouth
  • Decreased white blood cell count
  • Peripheral edema
  • Weakness
  • Impotence
  • Indigestion
  • Insomnia (difficulty in sleeping)
  • Tiredness
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Increased heart rate
  • Uncoordinated body movements
  • Constipation
  • Difficulty in urination
  • Weight gain
  • Sleepiness
  • Dizziness
  • Blurred vision

How to use NG 400mg/10mg Tablet:

Administer this medication precisely as your physician directs, adhering to both the prescribed dosage and treatment length. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. NG 400mg/10mg tablets can be consumed with or without food, although consistent timing is recommended.

How NG 400mg/10mg Tablet works:

Each NG 400mg/10mg tablet contains gabapentin and nortriptyline, working synergistically to alleviate neuropathic pain. Gabapentin, an alpha-2-delta calcium channel ligand, reduces pain transmission by modulating nerve cell calcium influx. Nortriptyline, a tricyclic antidepressant, elevates serotonin and noradrenaline levels, thus inhibiting pain signal propagation within the central nervous system. This combined action provides effective relief from nerve damage-related pain.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Concomitant use of NG 400mg/10mg tablets and alcohol may result in pronounced somnolence.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of NG 400mg/10mg tablets during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to a developing fetus. A physician will assess the potential advantages against any possible risks prior to prescribing this medication. Patient consultation with their doctor is advised.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Administration of NG 400mg/10mg tablets while breastfeeding is likely inadvisable. Available human data indicates potential transfer of the medication into breast milk, posing a possible risk to the infant.

DrivingDrivingUNSAFE

Driving ability may be impaired by NG 400mg/10mg Tablets, due to potential side effects that can reduce alertness.

KidneyKidneyCAUTION

Individuals with impaired kidney function should exercise caution when using NG 400mg/10mg tablets. Dosage modification may be necessary. Medical advice is recommended.

LiverLiverCAUTION

Patients with liver impairment should use the 400mg/10mg NG tablet cautiously, potentially requiring dosage modification. Consult a physician before use. Report any jaundice symptoms to your doctor immediately. The 400mg/10mg NG tablet is contraindicated in patients exhibiting severe hepatic dysfunction.

What if you forget to take NG 400mg/10mg Tablet :

Should you forget to take your NG 400mg/10mg Tablet, administer it immediately upon remembrance. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About NG 400mg/10mg Tablet

LabelValue
Developing Habits No.
Treatment Category Neuroscience

FAQs on NG 400mg/10mg Tablet

NG 400mg/10mg tablets combine gabapentin and nortriptyline to treat neuropathic pain. This medication soothes damaged or overly active nerves, reducing pain signals to the brain.
Don't discontinue NG 400mg/10mg Tablet even if your pain subsides. Follow your doctor's instructions. Abruptly stopping the medication can cause withdrawal symptoms including anxiety, insomnia, nausea, pain, and sweating. A gradual dose reduction is recommended before complete cessation.
Taking NG 400mg/10mg tablets may increase appetite, potentially leading to weight gain. Preventing this weight gain is simpler than losing it later. Maintain a balanced diet without larger portions. Avoid high-calorie foods like soft drinks, fried foods, chips, pastries, and sweets. Between meals, choose fruits, vegetables, and low-calorie options instead of junk food. Regular exercise further aids in preventing weight gain. Combining healthy eating and regular exercise may prevent any weight increase.
NG 400mg/10mg Tablets may impact sexual function in both men and women, potentially causing reduced libido, erectile dysfunction, difficulty achieving orgasm, decreased satisfaction, and discomfort during intercourse. If you experience these side effects, consult your doctor, but do not discontinue the medication without their advice.
While rare, serious side effects from NG 400mg/10mg tablets can occur. Seek immediate medical attention if you experience: altered body temperature, breathing difficulties, rapid heartbeat, weakness, gait instability, impaired coordination or slowed reflexes, unusual mood or behavior changes (including restlessness, anxiety, or agitation), depression, hallucinations, irrational thoughts, blurred or double vision, involuntary eye movements (nystagmus), vision problems, or signs of frequent infections (fever, chills, sore throat, mouth sores). These side effects, though infrequent, require prompt medical care.
You may notice initial improvements with NG 400mg/10mg tablets within two weeks, but complete effectiveness typically takes two to three months. Some individuals may require more time.
Missed a dose of your NG 400mg/10mg Tablet? If it's almost time for your next dose, skip the missed one. Otherwise, take it immediately and resume your regular schedule. Never double up on doses to compensate; this increases the risk of side effects. If unsure, consult your doctor.
If this occurs, get immediate medical help—either contact your doctor or go to the nearest emergency room. This is crucial even without symptoms. Overdosing can cause drowsiness, weakness, unsteady gait, double vision, slurred speech, diarrhea, confusion, blurred vision, dizziness, fluctuating body temperature, breathing difficulties, and rapid heartbeat.
NG 400mg/10mg Tablets can affect your alertness and coordination. Avoid driving or operating machinery. Refrain from alcohol consumption while taking this medication; it can heighten its effects. Grapefruit and grapefruit juice may interact negatively. Sunlight sensitivity is increased; wear protective clothing and sunscreen when outdoors.
Regular check-ups with your doctor are recommended while taking NG 400mg/10mg Tablets. Contact your doctor immediately if your symptoms don't improve with the prescribed dosage, or if you experience persistent side effects impacting your daily life.
NG 400mg/10mg Tablets can cause drowsiness and sudden sleepiness, potentially without warning. Therefore, avoid driving, operating machinery, working at heights, or engaging in hazardous activities, especially initially, until you understand the medication's effects on you. Report any such episodes to your doctor.
Exceeding the recommended dosage won't necessarily improve effectiveness; it could instead lead to serious side effects and toxicity. If your symptoms worsen despite taking the prescribed dose, consult your doctor for further assessment.
Leave tablets in their packaging until needed. Store in a cool, dry place, away from children's sight and reach. Dispose of unused medication properly to prevent accidental ingestion by children, pets, or others.
NG 400mg/10mg Tablet
176
MRP 215
18% off