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Nuprime G 400mg/10mg Tablet

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Prescription Required

Marketer

Zivago Pharma Private Limited

Salt Composition

Gabapentin (400mg) + Nortriptyline (10mg)

Overview Nuprime G 400mg/10mg Tablet

Combiflex-NP 400mg/10mg tablets offer relief from neuropathic pain by interrupting pain signal transmission to the brain. Administered orally, this medication can be taken with or without food, ideally at bedtime for consistent blood levels. If a dose is missed, take it immediately upon recollection. Complete the prescribed course, even with symptom improvement. Abrupt cessation should be avoided without consulting a physician, as it could exacerbate symptoms. Potential side effects include constipation, urinary difficulties, weight gain, fatigue, and dry mouth. Dizziness and drowsiness may occur; avoid driving or mentally demanding tasks until the drug's effects are understood. Weight gain is possible; counter this through regular exercise and a balanced diet. Report any unusual mood shifts to your doctor promptly, as suicidal thoughts may arise. Prior to commencing treatment, disclose any kidney or liver conditions, and all other medications being used, as interactions may reduce efficacy or alter the drug's action. Notify your physician if pregnant, planning pregnancy, or breastfeeding.

Uses of Nuprime G 400mg/10mg Tablet

Managing neuropathic pain

Major Benefits of Nuprime G 400mg/10mg Tablet:

Follow your doctor's instructions precisely regarding dosage and treatment length for Nuprime G 400mg/10mg Tablets. Ingest the tablets whole; avoid chewing, crushing, or breaking them. While consumption with or without food is acceptable, consistent daily timing is recommended.

Common Side effects of Nuprime G 400mg/10mg Tablet:

  • Dryness in mouth
  • Decreased white blood cell count
  • Peripheral edema
  • Weakness
  • Impotence
  • Indigestion
  • Insomnia (difficulty in sleeping)
  • Tiredness
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Increased heart rate
  • Uncoordinated body movements
  • Constipation
  • Difficulty in urination
  • Weight gain
  • Sleepiness
  • Dizziness
  • Blurred vision

How to use Nuprime G 400mg/10mg Tablet:

Consume this medication precisely as prescribed by your physician, adhering to both the dosage and treatment period. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Nuprime G 400mg/10mg Tablets can be administered with or without food, however, consistent timing is recommended.

How Nuprime G 400mg/10mg Tablet works:

Nuprime G 400mg/10mg tablets contain gabapentin and nortriptyline, working synergistically to alleviate neuropathic pain. Gabapentin, an alpha-2-delta ligand, reduces pain transmission by modulating nerve cell calcium channels. Nortriptyline, a tricyclic antidepressant, elevates serotonin and noradrenaline levels, thereby inhibiting pain signal propagation within the brain. This dual action effectively targets nerve damage-related pain.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Concomitant use of Nuprime G 400mg/10mg tablets and alcohol may result in pronounced somnolence.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Nuprime G 400mg/10mg tablets during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to the fetus. A physician will assess the potential advantages against any risks prior to prescribing this medication. Seek medical advice before taking this drug.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Limited evidence indicates that Nuprime G 400mg/10mg Tablet may pose a risk to breastfeeding infants due to potential transfer into breast milk. Therefore, its use during lactation is likely inadvisable.

DrivingDrivingUNSAFE

Driving ability may be impaired by Nuprime G 400mg/10mg Tablet, due to potential side effects that can reduce alertness.

KidneyKidneyCAUTION

Patients with kidney impairment should use Nuprime G 400mg/10mg tablets cautiously, as dosage modification may be necessary. Physician consultation is advised.

LiverLiverCAUTION

Patients with liver impairment should use the 400mg/10mg Nuprime G tablet cautiously, potentially requiring dosage modification. Consult your physician. Report any jaundice symptoms to your doctor immediately while using this medication. Nuprime G 400mg/10mg tablets are contraindicated in patients with severe hepatic dysfunction.

What if you forget to take Nuprime G 400mg/10mg Tablet :

Should you forget a Nuprime G 400mg/10mg Tablet dose, administer it promptly. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Nuprime G 400mg/10mg Tablet

LabelValue
Developing Good Habits No.
Treatment Category Neuroscience (Central Nervous System)

FAQs on Nuprime G 400mg/10mg Tablet

Nuprime G 400mg/10mg tablets combine gabapentin and nortriptyline to treat neuropathic pain. It works by calming overactive or damaged nerves in the brain, reducing pain sensations.
Don't discontinue Nuprime G 400mg/10mg Tablet even if your pain subsides. Follow your doctor's instructions. Abrupt cessation may cause withdrawal symptoms including anxiety, insomnia, nausea, pain, and sweating. A gradual dose reduction is recommended before stopping the medication entirely.
Nuprime G 400mg/10mg Tablets may increase appetite, potentially leading to weight gain. Preventing this weight gain is simpler than losing it later. Maintain a healthy, balanced diet without larger portions. Avoid high-calorie foods like soft drinks, fried foods, chips, cakes, biscuits, and sweets. Between meals, choose fruits, vegetables, and low-calorie options instead of junk food. Regular exercise further helps prevent weight gain. Combining healthy eating and regular exercise may prevent any weight increase.
Nuprime G 400mg/10mg Tablet may impact sexual function in both men and women, potentially causing reduced libido, erectile dysfunction (difficulty achieving or maintaining an erection), and difficulty reaching orgasm. Decreased sexual satisfaction and discomfort during intercourse may also occur. Report any such issues to your doctor, but do not discontinue Nuprime G 400mg/10mg Tablet without medical advice.
Nuprime G 400mg/10mg Tablet rarely causes serious side effects. However, seek immediate medical attention if you experience: altered body temperature, breathing difficulties, rapid heartbeat, weakness, gait instability, impaired coordination or slowed reflexes, unusual mood or behavior changes (including restlessness, anxiety, or agitation), depression, hallucinations, irrational thoughts, blurred or double vision, involuntary eye movements, vision problems, or signs of frequent infections (fever, chills, sore throat, or mouth sores). While infrequent, these side effects require prompt medical care.
You may notice initial improvements with Nuprime G 400mg/10mg tablets within two weeks, but full benefits typically appear after two to three months. Some individuals may require a longer treatment period.
Missed a dose of Nuprime G 400mg/10mg? If it's almost time for your next dose, skip the missed one and continue as usual. Otherwise, take it immediately and resume your regular schedule. Never double up on doses; this can cause harmful side effects. If unsure, consult your doctor.
Seek immediate medical attention, contacting your doctor or going to the nearest hospital, even without noticeable symptoms. Urgent care may be necessary. Overdosing on this medication can cause drowsiness, weakness, gait instability, diplopia, slurred speech, diarrhea, confusion, blurred vision, dizziness, fluctuating body temperature, respiratory distress, and tachycardia.
Nuprime G 400mg/10mg Tablets may affect your alertness and coordination. Avoid driving or operating machinery while taking this medication. Alcohol consumption should be avoided as it can intensify the drug's effects. Grapefruit and grapefruit juice may interact negatively; avoid them. Increased sun sensitivity is possible; wear protective clothing and sunscreen when outdoors.
Regular checkups with your doctor are recommended while taking Nuprime G 400mg/10mg Tablet. Consult your doctor immediately if your symptoms don't improve with the prescribed dosage, or if you experience persistent side effects impacting your daily life.
Nuprime G 400mg/10mg Tablets can cause drowsiness and sudden sleep onset, sometimes without warning. Avoid potentially hazardous activities like driving, operating machinery, or working at heights, especially initially, until you understand the medication's effects on you. Report any such sleep episodes to your doctor.
Exceeding the recommended dosage won't necessarily improve results; it could instead lead to severe side effects and toxicity. If your symptoms worsen despite taking the prescribed dose, seek medical advice.
Leave tablets in their packaging until needed. Store in a cool, dry place, safely out of reach and sight of children. Dispose of unused medication properly to prevent accidental ingestion by children, pets, or others.
Nuprime G 400mg/10mg Tabl...
15
MRP 17
11% off