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Pemgli-M1 Tablet SR

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Prescription Required

Marketer

Superlative Healthcare

Salt Composition

Glimepiride (1mg) + Metformin (500mg)

Overview Pemgli-M1 Tablet SR

Dia-Comb SR tablets are classified as antidiabetic medications. This dual-action formulation treats type 2 diabetes in adults by regulating blood glucose. Dia-Comb SR should be ingested with meals, consistently at the same time daily for optimal efficacy. Dosage is determined and adjusted by your physician based on your blood sugar response. Continued use is crucial, even with well-managed glucose levels, as abrupt cessation can lead to elevated blood sugar, increasing the risk of complications like kidney impairment, vision loss, neuropathy, and limb amputation. Remember, this medication complements a comprehensive diabetes management plan including diet, exercise, and weight management as directed by your doctor. Lifestyle choices significantly impact diabetes control. Hypoglycemia (low blood sugar) is the most frequent side effect, characterized by symptoms like sweating, dizziness, headache, and tremors. Regular meals and readily available fast-acting glucose sources (e.g., sugary foods, fruit juice) are essential for prevention. Alcohol consumption increases hypoglycemia risk and should be avoided. Additional possible side effects include altered taste, nausea, diarrhea, abdominal discomfort, headache, and upper respiratory infections. Weight gain may occur. This medication is contraindicated in type 1 diabetes, diabetic ketoacidosis, and severe hepatic or renal impairment. Prior heart conditions should be disclosed to your physician before commencing treatment. Pregnant or lactating individuals require medical consultation before use. Regular blood glucose monitoring is necessary, and your doctor may order blood tests to assess blood cell counts and liver function.

Uses of Pemgli-M1 Tablet SR

Managing type 2 diabetes

Major Benefits of Pemgli-M1 Tablet SR:

Follow your doctor's instructions precisely regarding the dosage and treatment length for this medication. Ingest the Pemgli-M1 Tablet SR whole; avoid chewing, crushing, or fracturing it. Administer this medication with food.

Common Side effects of Pemgli-M1 Tablet SR:

  • Headache
  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Diarrhea

How to use Pemgli-M1 Tablet SR:

Consume this medication precisely as your physician directs, adhering to both the prescribed dosage and treatment length. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. It's recommended to take Pemgli-M1 Tablet SR with a meal.

How Pemgli-M1 Tablet SR works:

Pemgli-M1 SR tablets contain glimepiride and metformin, two medications used to manage diabetes. Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin, thus reducing blood sugar. Metformin, a biguanide, acts through multiple mechanisms: decreasing hepatic glucose production, slowing intestinal glucose absorption, and enhancing insulin sensitivity.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Alcohol consumption alongside Pemgli-M1 SR tablets is inadvisable.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Pemgli-M1 Tablet SR during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to a developing fetus. A physician will assess the potential benefits against any risks prior to prescription. Consult your doctor for advice.

Breast feedingBreast feedingUNSAFE

Extended-release Pemgli-M1 tablets are contraindicated for use while breastfeeding due to potential infant toxicity.

DrivingDrivingCAUTION

Driving ability can be impaired by both hypoglycemia and hyperglycemia. Refrain from driving if you experience these blood sugar imbalances.

KidneyKidneyCAUTION

Patients with kidney impairment should use Pemgli-M1 SR tablets cautiously, potentially requiring dosage modification. Severe kidney disease contraindicates Pemgli-M1 SR tablet use. Physician consultation is essential. Regular kidney function monitoring is recommended during treatment.

LiverLiverCAUTION

Individuals with liver impairment should use Pemgli-M1 Tablet SR cautiously, potentially requiring dosage modification. Consult your physician. A reduced initial dose is typically recommended for those with mild to moderate liver disease; the medication is contraindicated in patients with severe hepatic dysfunction.

What if you forget to take Pemgli-M1 Tablet SR :

Should you forget a Pemgli-M1 Tablet SR dose, take it immediately. Nevertheless, if your next dose is imminent, omit the missed dose and resume your usual dosing pattern. Never take a double dose.

Facts to Know About Pemgli-M1 Tablet SR

LabelValue
Developing Habits No.
Treatment Category Diabetes Management

FAQs on Pemgli-M1 Tablet SR

Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication and ensure it's inaccessible to children, pets, and others.
Pemgli-M1 Tablet SR can cause lactic acidosis, a serious medical emergency characterized by excessive blood lactic acid (also known as MALA, or Metformin-associated lactic acidosis). This rare but potentially harmful side effect is more likely in patients with kidney disease, older adults, or those who consume significant amounts of alcohol. Symptoms include muscle pain or weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and slow heart rate. If you experience these, discontinue Pemgli-M1 Tablet SR and seek immediate medical attention.
Pemgli-M1 Tablet SR combines glimepiride and metformin to manage type 2 diabetes mellitus (DM) in adults. This medication improves blood glucose control when used with diet and exercise. Glimepiride enhances insulin release from the pancreas, while metformin reduces liver glucose production and improves insulin sensitivity. It's not suitable for type 1 DM.
Pemgli-M1 Tablet SR may cause common side effects such as low blood sugar (hypoglycemia), altered taste, nausea, stomach pain, diarrhea, and headache. Rare but serious side effects include lactic acidosis. Prolonged use can also result in vitamin B12 deficiency.
Prolonged Pemgli-M1 Tablet SR use can lead to vitamin B12 deficiency by hindering its absorption. This deficiency, if left unaddressed, may result in anemia, neurological issues such as tingling, numbness in extremities, weakness, urinary problems, cognitive changes, and ataxia. To mitigate these risks, supplemental vitamin B12 intake at least annually is recommended by some researchers.
Yes, Pemgli-M1 Tablet SR can lower your blood sugar, potentially causing hypoglycemia. Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, rapid heartbeat, and shakiness or anxiety. This risk increases if you skip meals, drink alcohol, overexert yourself, or take other diabetes medications. Regular blood sugar monitoring is crucial. Always carry a fast-acting sugar source, such as glucose tablets, honey, or fruit juice.
Combining Pemgli-M1 Tablet SR and alcohol is unsafe. Alcohol can further reduce blood sugar, risking hypoglycemia, and increase the likelihood of lactic acidosis.
Pemgli-M1 Tablet SR
42
MRP 51
17% off