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Pentanerv-NT Tablet

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Prescription Required

Marketer

Alkem Laboratories Ltd

Salt Composition

Gabapentin (400mg) + Nortriptyline (10mg)

Overview Pentanerv-NT Tablet

Neuropathic pain is addressed by the combination medication Pentanerv-NT, administered orally. Its mechanism involves interrupting pain signal transmission to the brain, thus reducing pain perception. Dosage is typically once daily, preferably at bedtime, with or without food, ensuring consistent blood levels. Missed doses should be taken promptly upon recall; complete the prescribed course regardless of symptom improvement. Abrupt cessation is discouraged; consult your physician before discontinuing to avoid potential symptom exacerbation. Common side effects include constipation, urinary difficulties, weight gain, fatigue, and dry mouth. Dizziness and drowsiness may occur, necessitating caution with activities requiring alertness. Weight gain can be mitigated through diet and exercise. Report any unusual mood shifts immediately, as suicidal ideation is a potential risk. Prior to commencing treatment, disclose any kidney or liver conditions, and provide a complete list of current medications, as interactions may affect efficacy. Pregnancy, pregnancy planning, and breastfeeding should also be reported to your doctor.

Uses of Pentanerv-NT Tablet

Managing neuropathic pain

Major Benefits of Pentanerv-NT Tablet:

Follow your doctor's instructions precisely regarding dosage and treatment length for this medication. Ingest the tablet whole; avoid chewing, crushing, or breaking it. Pentanerv-NT Tablets can be consumed with or without food, although consistent timing is recommended.

Common Side effects of Pentanerv-NT Tablet:

  • Dryness in mouth
  • Decreased white blood cell count
  • Peripheral edema
  • Weakness
  • Impotence
  • Indigestion
  • Insomnia (difficulty in sleeping)
  • Tiredness
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Increased heart rate
  • Uncoordinated body movements
  • Constipation
  • Difficulty in urination
  • Weight gain
  • Sleepiness
  • Dizziness
  • Blurred vision

How to use Pentanerv-NT Tablet:

Consume this medication precisely as your physician directs, adhering to both the prescribed dosage and treatment period. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Pentanerv-NT Tablets can be taken with or without food, however, consistency in timing is recommended.

How Pentanerv-NT Tablet works:

Pentanerv-NT tablets contain gabapentin and nortriptyline, working synergistically to alleviate neuropathic pain. Gabapentin, an alpha-2-delta ligand, reduces pain perception by modulating nerve cell calcium channel function. Nortriptyline, a tricyclic antidepressant, elevates serotonin and noradrenaline, neurotransmitters that inhibit pain signal transmission within the brain. This combined action provides effective relief from nerve damage-related pain.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Concurrent use of Pentanerv-NT tablets and alcohol may result in significant sedation.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Pentanerv-NT Tablets during pregnancy may pose risks. While human research is scant, animal studies indicate potential harm to the fetus. A physician will assess the potential benefits against any risks prior to prescribing. Seek medical advice before using this medication.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Use of Pentanerv-NT tablets while breastfeeding is likely inadvisable. Available human data indicates potential transfer to breast milk, posing a possible risk to the infant.

DrivingDrivingUNSAFE

Driving ability may be impaired by side effects associated with Pentanerv-NT Tablets, due to potential drowsiness.

KidneyKidneyCAUTION

Patients with kidney impairment should use Pentanerv-NT Tablets cautiously; dosage modification may be necessary. Physician consultation is advised.

LiverLiverCAUTION

Patients with liver impairment should exercise caution when using Pentanerv-NT Tablets, potentially requiring dosage modification. Physician consultation is advised. Report any jaundice symptoms to your doctor immediately. Pentanerv-NT Tablets are contraindicated in patients exhibiting severe hepatic dysfunction.

What if you forget to take Pentanerv-NT Tablet :

Should you forget a Pentanerv-NT Tablet dose, administer it promptly. Nevertheless, if your next scheduled dose is imminent, omit the missed one and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Pentanerv-NT Tablet

LabelValue
Addictive None.
Medication Classification Central and peripheral nervous system.

FAQs on Pentanerv-NT Tablet

Gabapentin and Nortriptyline, combined as Pentanerv-NT Tablets, offer relief from neuropathic pain. The medication works by modulating the activity of damaged or hypersensitive nerves within the central nervous system, thus reducing pain perception.
Discontinuing Pentanerv-NT Tablet prematurely, even with pain relief, is inadvisable. Follow your physician's instructions for its continued use. Abrupt cessation may lead to withdrawal effects including agitation, insomnia, nausea, pain recurrence, and diaphoresis. A gradual dosage reduction is recommended prior to complete discontinuation.
Pentanerv-NT Tablets may increase appetite, potentially leading to weight gain. Weight management is simpler than weight loss. Maintain a nutritious, balanced diet without enlarging meal portions. Restrict high-calorie foods like sugary drinks, fried foods, processed snacks, and desserts. Between meals, choose fruits, vegetables, and low-calorie options instead of junk food. Regular physical activity aids in preventing weight gain. Consistent healthy eating and exercise may prevent any weight increase.
Pentanerv-NT Tablets may impact sexual function in both genders. Reported issues include reduced libido, erectile dysfunction (difficulty achieving or sustaining an erection), and anorgasmia. Decreased sexual satisfaction and discomfort during intercourse may also occur. Consult your physician if these effects arise, but continue taking Pentanerv-NT Tablets unless otherwise advised.
Pentanerv-NT Tablet rarely causes severe adverse reactions. Seek immediate medical advice if you experience: altered body temperature, respiratory distress, rapid heartbeat, fatigue, gait instability, impaired coordination or slowed reflexes, atypical mood or behavior shifts (including agitation, anxiety, or euphoria), depressive symptoms, hallucinations, illogical thought processes, visual disturbances (blurred or double vision), involuntary eye movements, vision impairment, or indicators of recurrent infections like fever, intense chills, pharyngitis, or oral ulcers. While infrequent, these side effects necessitate prompt medical care.
Patients may experience initial improvements with Pentanerv-NT Tablets within two weeks, though complete therapeutic effects typically manifest within two to three months. Some individuals may require a longer treatment duration to achieve optimal results.
Should you miss a scheduled Pentanerv-NT Tablet dose, and your next dose is imminent, omit the missed dose and continue with your regular schedule. If your next dose is not soon, take the missed dose immediately upon recollection, then resume your usual dosing pattern. Never double the dose to compensate for a missed one; this raises the likelihood of adverse reactions from an overdose. For any uncertainty regarding Pentanerv-NT Tablet administration, consult your physician.
If this occurs, promptly contact your physician or proceed directly to the nearest emergency room. Seek medical assistance regardless of the presence or absence of symptoms. An overdose might manifest as drowsiness, weakness, gait instability, diplopia, dysarthria, diarrhea, disorientation, blurred vision, vertigo, fluctuating body temperature, respiratory distress, and tachycardia.
Using Pentanerv-NT Tablets may affect cognitive function and reaction time. Exercise caution when operating machinery or engaging in activities demanding alertness. Alcohol consumption should be avoided during treatment with Pentanerv-NT Tablets due to the potential for intensified effects. Grapefruit and its juice may interact negatively with this medication, leading to adverse reactions. Limit sun exposure and avoid tanning beds; Pentanerv-NT Tablets increase sun sensitivity. Wear protective clothing and sunscreen when outside during daylight hours.
Regular check-ups with your physician are recommended following commencement of Pentanerv-NT Tablet therapy. Consult your doctor immediately if your symptoms fail to improve with the prescribed Pentanerv-NT Tablet dosage, or if persistent adverse effects interfere with your daily life.
Pentanerv-NT Tablets can induce drowsiness and may lead to unexpected sleep onset during routine tasks. This sudden sleepiness may occur without prior warning signs like drowsiness. Refrain from driving, operating equipment, working at heights, or engaging in hazardous activities, especially initially, until the medication's effects are understood. Report any such sleep episodes to your physician while using this medication.
Increasing the prescribed dosage won't necessarily improve results; in fact, it could heighten the risk of severe adverse reactions and harmful effects. If your symptoms worsen despite taking the recommended amount, seek medical advice for reassessment.
Retain medication within its original packaging until needed. Store in a cool, dry location. Keep the medication out of children's view and reach. Proper disposal of any remaining medicine is crucial to prevent accidental ingestion by children, pets, or others.
Pentanerv-NT Tablet
367
MRP 447
17% off