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Pregavex Trio Tablet SR

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Prescription Required

Marketer

Thrivex Lifesciences Pvt. Ltd.

Salt Composition

Pregabalin (75mg) + Nortriptyline (10mg) + Methylcobalamin (1500mcg)

Overview Pregavex Trio Tablet SR

Neuropathic pain relief is provided by the sustained-release Pregavex Trio Tablet, a multi-component medication. Its mechanism involves modulating nerve cell calcium channel activity to reduce pain signals. Concurrently, it elevates levels of brain neurotransmitters that stabilize mood and safeguard nerve tissue. Pregavex Trio Tablet SR may be administered with or without food, but consistent daily timing ensures therapeutic drug levels. Adhere strictly to your physician's prescribed dosage and duration. Missed doses should be taken immediately upon recollection. Complete the entire course of treatment, even with symptom improvement. Abrupt cessation is discouraged due to potential symptom exacerbation. Common adverse effects include constipation, weight increase, and xerostomia. Drowsiness and dizziness may occur; avoid activities requiring alertness until the drug's impact is known. Weight gain can be mitigated through a balanced diet and regular physical activity. Report any unusual mood shifts, behavioral changes, new or worsening depression, or suicidal ideation to your doctor immediately. Prior to commencing treatment, disclose any kidney or liver conditions, and provide a comprehensive list of all other medications being taken, as interactions may affect efficacy or mechanism. Notify your doctor if you are pregnant, considering pregnancy, or breastfeeding.

Primary Ingredients of Pregavex Trio Tablet SR

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Uses of Pregavex Trio Tablet SR

Managing neuropathic pain

Major Benefits of Pregavex Trio Tablet SR:

Administer this medication precisely as prescribed by your physician, adhering to both the dosage and treatment schedule. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Pregavex Trio Tablet SR can be consumed with or without food, although consistent timing is recommended.

Common Side effects of Pregavex Trio Tablet SR:

  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Increased heart rate
  • Difficulty in urination
  • Decreased appetite
  • Nausea
  • Vomiting
  • Constipation
  • Weight gain
  • Dizziness
  • Sleepiness
  • Tiredness
  • Blurred vision
  • Dryness in mouth
  • Uncoordinated body movements
  • Diarrhea
  • Headache

How to use Pregavex Trio Tablet SR:

Administer this medication precisely as your physician directs, adhering to both the prescribed dosage and treatment length. Ingest the tablet whole; avoid chewing, crushing, or breaking it. Pregavex Trio Tablet SR can be consumed with or without food, although consistent timing is recommended.

How Pregavex Trio Tablet SR works:

Pregavex Trio SR tablets contain pregabalin, nortriptyline, and methylcobalamin, working synergistically to alleviate neuropathic pain. Pregabalin, an alpha-2-delta calcium channel ligand, reduces pain transmission by modulating nerve cell calcium influx. Nortriptyline, a tricyclic antidepressant, elevates serotonin and noradrenaline levels, thus inhibiting pain signal transmission within the central nervous system. Methylcobalamin, a vitamin B12 derivative, promotes myelin sheath regeneration, protecting and repairing damaged nerve fibers. This combined action provides effective relief from nerve-related pain.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Concurrent use of Pregavex Trio Tablet SR and alcohol may result in significant somnolence.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Pregavex Trio Tablet SR during pregnancy may pose risks. While human data is scarce, animal studies indicate potential harm to the fetus. A physician will assess the advantages against possible dangers prior to prescription. Seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

The extended-release Pregavex Trio Tablet is likely unsafe for breastfeeding mothers. Available human data indicates potential transfer to breast milk, posing a possible risk to the infant.

DrivingDrivingUNSAFE

Driving ability may be impaired by Pregavex Trio Tablet SR due to potential side effects that can reduce alertness.

KidneyKidneyCAUTION

Patients with kidney impairment should exercise caution when using Pregavex Trio Tablet SR. A modified dosage of Pregavex Trio Tablet SR might be necessary. Physician consultation is advised.

LiverLiverSAFE IF PRESCRIBED

The use of Pregavex Trio Tablet SR in individuals with hepatic impairment is likely safe. Current evidence indicates dose modification may not be necessary, however, physician consultation is recommended.

What if you forget to take Pregavex Trio Tablet SR :

Should you forget a Pregavex Trio Tablet SR dose, administer it at your earliest convenience. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing pattern. Avoid taking a double dose.

Facts to Know About Pregavex Trio Tablet SR

LabelValue
Developing Habits No.
Type of Therapy Neuroscience of the Central Nervous System

FAQs on Pregavex Trio Tablet SR

Pregavex Trio SR tablets combine gabapentin, nortriptyline, and methylcobalamin to treat neuropathic pain. It soothes damaged or overactive nerves, reducing pain signals to the brain, and promotes nerve regeneration.
Don't discontinue Pregavex Trio Tablet SR prematurely, even if your pain subsides. Follow your doctor's instructions. Abrupt cessation may cause withdrawal symptoms including anxiety, insomnia, nausea, pain, and sweating. A gradual dose reduction is recommended before complete discontinuation.
Pregavex Trio Tablet SR may increase appetite, potentially leading to weight gain. Preventing this weight gain is simpler than losing it later. Maintain a balanced diet with controlled portion sizes, avoiding high-calorie foods like sugary drinks, fried foods, chips, and sweets. Between meals, choose fruits, vegetables, and low-calorie snacks instead of junk food. Regular exercise further helps prevent weight gain. Combining healthy eating and regular exercise may avoid weight gain altogether.
Pregavex Trio Tablet SR may cause drowsiness or sudden sleepiness, sometimes without warning. Until you understand its effects, avoid driving, operating machinery, working at heights, or other hazardous activities. Report any such episodes to your doctor.
Pregavex Trio Tablet SR may impact sexual function in both men and women, potentially causing reduced libido, erectile dysfunction (difficulty achieving or maintaining an erection), and anorgasmia (inability to achieve orgasm). Decreased sexual satisfaction and discomfort during intercourse are also possible. If these occur, consult your doctor, but do not discontinue Pregavex Trio Tablet SR without medical advice.
Pregavex Trio Tablet SR rarely causes serious side effects. Seek immediate medical help if you experience: altered body temperature, breathing difficulties, rapid heartbeat, weakness, gait instability, poor coordination, slowed reflexes, unusual mood or behavior shifts (restlessness, anxiety, or agitation), depression, hallucinations, disordered thinking, blurred or double vision, involuntary eye movements (nystagmus), visual disturbances, or signs of infection (fever, chills, sore throat, mouth sores). While infrequent, these side effects require prompt medical attention.
Pregavex Trio Tablet SR may show initial improvements within two weeks, but complete benefits may take two to three months or longer.
Missed a Pregavex Trio Tablet SR dose? If it's nearly time for your next dose, skip the missed one. Otherwise, take it immediately and resume your regular schedule. Never double the dose; this could cause side effects. If unsure, contact your doctor for guidance.
Seek immediate medical attention—contact your doctor or go to the nearest emergency room—even without noticeable symptoms. Urgent care may be necessary. Overdose symptoms can include drowsiness, weakness, gait instability, diplopia, slurred speech or diarrhea, confusion, blurred vision, dizziness, fluctuating body temperature, respiratory distress, and tachycardia.
Increased dosage beyond the recommended amount won't necessarily improve effectiveness; it could instead lead to severe side effects and toxicity. If your symptoms worsen despite taking the prescribed dose, seek medical advice.
Pregavex Trio Tablet SR can affect your alertness and coordination. Avoid driving or operating machinery. Refrain from alcohol consumption while using this medication as it can intensify its effects. Grapefruit and grapefruit juice may interact negatively; therefore, avoid them. Increased sun sensitivity is a potential side effect; wear protective clothing and sunscreen when outdoors.
Regular check-ups with your doctor are recommended while taking Pregavex Trio Tablet SR. If your symptoms don't improve with the prescribed dosage, or if side effects interfere with your daily life, consult your doctor immediately.
Don't open the tablet pack until needed. Store the pack in a cool, dry place, away from children. Dispose of unused medication properly to prevent accidental ingestion by children, pets, or others.
Pregavex Trio Tablet SR does have an expiration date. Check the packaging for this date and do not use the medication after it expires.
Pregavex Trio Tablet SR
186
MRP 215
13% off