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PREMAC PLUS 50mg/10mg/1500mcg Tablet

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Prescription Required

Marketer

Antila Lifesciences Pvt Ltd

Salt Composition

Pregabalin (50mg) + Nortriptyline (10mg) + Methylcobalamin (1500mcg)

Overview PREMAC PLUS 50mg/10mg/1500mcg Tablet

Combiflex NR 50mg/10mg/1500mcg tablets alleviate neuropathic pain by modulating nerve cell calcium channel activity. This three-component formulation also boosts brain neurotransmitters, improving mood and safeguarding nerve health. Combiflex NR may be taken with or without food, but consistent daily timing ensures stable blood levels. Always follow your physician's prescribed dosage and duration; if a dose is missed, take it immediately upon recall. Complete the entire course, even with symptom improvement, and avoid abrupt cessation to prevent symptom exacerbation. Common side effects include constipation, weight increase, and dry mouth. Dizziness and drowsiness are possible; avoid driving or mentally demanding tasks until effects are known. Weight gain can occur; a balanced diet and regular exercise are recommended. Report any unusual mood shifts, new or worsening depression, or suicidal ideation to your doctor immediately. Prior to commencing treatment, disclose any kidney or liver conditions, and provide a complete list of all current medications, as interactions may reduce efficacy or alter the drug's action. Inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Primary Ingredients of PREMAC PLUS 50mg/10mg/1500mcg Tablet

There is no text provided to rewrite.

Uses of PREMAC PLUS 50mg/10mg/1500mcg Tablet

Managing Neuropathic Pain

Major Benefits of PREMAC PLUS 50mg/10mg/1500mcg Tablet:

Follow your doctor's instructions precisely regarding dosage and treatment length for this medication. Ingest the PREMAC PLUS 50mg/10mg/1500mcg Tablet whole; do not chew, crush, or divide it. Consumption with or without food is acceptable, although consistent timing is recommended.

Common Side effects of PREMAC PLUS 50mg/10mg/1500mcg Tablet:

  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Increased heart rate
  • Difficulty in urination
  • Decreased appetite
  • Nausea
  • Vomiting
  • Constipation
  • Weight gain
  • Dizziness
  • Sleepiness
  • Tiredness
  • Blurred vision
  • Dryness in mouth
  • Uncoordinated body movements
  • Diarrhea
  • Headache

How to use PREMAC PLUS 50mg/10mg/1500mcg Tablet:

Follow your doctor's instructions precisely regarding dosage and treatment length for this medication. Ingest the PREMAC PLUS 50mg/10mg/1500mcg Tablet whole; avoid crushing, chewing, or breaking it. This medication can be administered with or without food, although consistent timing is recommended.

How PREMAC PLUS 50mg/10mg/1500mcg Tablet works:

PREMAC PLUS 50mg/10mg/1500mcg tablets combine pregabalin, nortriptyline, and methylcobalamin to alleviate neuropathic pain. Pregabalin, an alpha-2-delta ligand, reduces pain by modifying nerve cell calcium channel function. Nortriptyline, a tricyclic antidepressant, elevates serotonin and noradrenaline, neurotransmitters that inhibit pain signal transmission to the brain. Methylcobalamin, a vitamin B12 variant, supports myelin production, protecting nerve fibers and promoting nerve cell repair. This synergistic action provides comprehensive neuropathic pain relief.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Concurrent use of PREMAC PLUS 50mg/10mg/1500mcg tablets and alcohol may lead to increased sleepiness.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of PREMAC PLUS 50mg/10mg/1500mcg Tablets during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to the fetus. A physician will assess the potential advantages against any risks before prescribing. Seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

The use of PREMAC PLUS 50mg/10mg/1500mcg tablets while breastfeeding is likely inadvisable. Scant evidence from human studies indicates potential transfer of the medication into breast milk, posing a risk to the infant.

DrivingDrivingUNSAFE

Driving ability may be impaired by PREMAC PLUS 50mg/10mg/1500mcg Tablet, due to potential side effects that can reduce alertness.

KidneyKidneyCAUTION

Patients with kidney impairment should use PREMAC PLUS 50mg/10mg/1500mcg tablets cautiously, as dose modification may be necessary. Physician consultation is advised.

LiverLiverSAFE IF PRESCRIBED

The use of PREMAC PLUS 50mg/10mg/1500mcg tablets in patients with liver disease is likely safe. Available evidence indicates dose modification may be unnecessary; however, physician consultation is recommended.

What if you forget to take PREMAC PLUS 50mg/10mg/1500mcg Tablet :

Should you forget a dose of PREMAC PLUS 50mg/10mg/1500mcg Tablet, administer it at your earliest convenience. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About PREMAC PLUS 50mg/10mg/1500mcg Tablet

LabelValue
Potential for Dependence None.
Medication Classification Nervous system medication

FAQs on PREMAC PLUS 50mg/10mg/1500mcg Tablet

PREMAC PLUS 50mg/10mg/1500mcg tablets contain gabapentin, nortriptyline, and methylcobalamin. This combination medication treats neuropathic pain by modulating the activity of damaged or overly sensitive nerves within the brain, thus reducing pain perception. It further aids in the repair of damaged nerves.
Discontinuing PREMAC PLUS 50mg/10mg/1500mcg Tablet, even with pain relief, is inadvisable. Follow your physician's instructions for its use. Abrupt cessation may result in withdrawal effects including anxiety, insomnia, nausea, pain recurrence, and diaphoresis. A gradual dose reduction is recommended prior to complete discontinuation.
Taking PREMAC PLUS 50mg/10mg/1500mcg Tablets may increase appetite, leading to potential weight gain. Managing weight gain is simpler than subsequent weight loss. Maintain a nutritious, balanced diet without enlarging portions. Limit high-calorie foods like soda, fried foods, potato chips, pastries, cookies, and candy. Between meals, choose fruits, vegetables, and low-calorie options instead of unhealthy snacks. Regular physical activity aids in preventing weight gain. Consistent healthy eating and exercise may prevent any weight increase.
Taking PREMAC PLUS 50mg/10mg/1500mcg Tablets can cause drowsiness or sudden sleep onset during routine tasks. This sleepiness may occur without warning. Therefore, refrain from driving, operating equipment, working at heights, or engaging in risky activities, especially when starting treatment, until you understand the medication's effects on you. Report any such incidents to your physician while using this medication.
PREMAC PLUS 50mg/10mg/1500mcg Tablets may impact sexual function in both genders. Reduced libido, erectile dysfunction (difficulty achieving or sustaining an erection), and anorgasmia are frequently reported. Decreased sexual satisfaction and discomfort during intercourse are also possible side effects. Consult your physician if such issues arise; however, do not discontinue PREMAC PLUS 50mg/10mg/1500mcg Tablets without medical advice.
Infrequent and rare adverse reactions have been associated with PREMAC PLUS 50mg/10mg/1500mcg Tablet. Seek immediate medical advice if you experience: altered body temperature, respiratory distress, rapid heartbeat, fatigue, gait instability, impaired motor control or sluggish reflexes, atypical mood or behavior (including agitation, anxiety, or euphoria), depressive symptoms, hallucinations, delusional thinking, visual disturbances (blurriness or diplopia), involuntary eye movements, visual impairment, or symptoms suggestive of recurrent infections like pyrexia, rigors, pharyngitis, or oral ulcers. While uncommon, these reactions warrant prompt medical intervention.
The onset of effects from PREMAC PLUS 50mg/10mg/1500mcg Tablet may begin within two weeks. Complete therapeutic effects, however, might require two to three months or longer.
Should you miss a dose of PREMAC PLUS 50mg/10mg/1500mcg Tablet, and your next dose is nearly due, omit the missed dose and continue with your regular schedule. If your next dose is not imminent, take the missed dose immediately upon remembering, then resume your usual medication regimen. Avoid doubling up on doses to compensate for a missed one; this could heighten the risk of adverse reactions. For any uncertainty regarding missed doses, seek advice from your healthcare provider.
If this occurs, promptly contact your physician or proceed to the closest emergency room. Seek medical assistance regardless of the presence or absence of adverse effects. Immediate intervention may be necessary. Overdose symptoms can manifest as lethargy, fatigue, gait instability, diplopia, dysarthria, diarrhea, disorientation, blurred vision, vertigo, fluctuating body temperature, respiratory distress, and tachycardia.
Increasing the prescribed dosage won't necessarily improve results; in fact, it could heighten the risk of severe adverse reactions and harmful effects. If your symptoms worsen despite adhering to the recommended dosage, seek medical advice for reassessment.
Taking PREMAC PLUS 50mg/10mg/1500mcg Tablets may reduce alertness and impair cognitive function. Exercise caution when operating machinery or engaging in activities demanding concentration. Alcohol consumption should be avoided during treatment with PREMAC PLUS 50mg/10mg/1500mcg Tablets due to the potential for intensified effects and increased risk. Grapefruit and grapefruit juice can interact negatively, potentially causing adverse reactions; therefore, their consumption should be avoided. Increased sun sensitivity is a potential side effect; minimize sun exposure and use protective clothing and sunscreen when outdoors during daylight hours.
Scheduled check-ups with your physician are recommended following commencement of PREMAC PLUS 50mg/10mg/1500mcg Tablet therapy. Consult your doctor immediately if your symptoms fail to improve with the prescribed dose of PREMAC PLUS 50mg/10mg/1500mcg Tablet, or if you encounter adverse effects impacting your daily life.
Protect your medication by keeping it in its original packaging until needed. Store the tablets in a cool, dry location, inaccessible to children. Proper disposal of any leftover medication is crucial to prevent accidental ingestion by children, pets, or others.
PREMAC PLUS 50mg/10mg/1500mcg Tablets have an expiration date. Confirm the expiration date printed on the product packaging. Discard PREMAC PLUS 50mg/10mg/1500mcg Tablets after this date.
PREMAC PLUS 50mg/10mg/150...
111
MRP 136
18% off