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Pretual NT 75mg/10mg Tablet

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Perpetual Pharmaceuticals

Salt Composition

Pregabalin (75mg) + Nortriptyline (10mg)

Overview Pretual NT 75mg/10mg Tablet

Combiflam NT 75mg/10mg tablets offer relief from neuropathic pain by interrupting pain signal transmission to the brain. Administered orally, this medication can be taken with or without food, ideally before sleep, at the same time daily for consistent blood levels. Follow your doctor's prescribed dosage and duration precisely, as this medication can be habit-forming. Missed doses should be taken immediately upon recall. Complete the entire course, even with symptom improvement. Discontinue use only under medical supervision. Common side effects include constipation, urination difficulties, weight gain, fatigue, and dry mouth; dizziness and drowsiness may also occur, necessitating caution with activities requiring alertness. Weight gain is possible; maintain a healthy diet and exercise routine to mitigate this. Report any unusual mood or behavioral shifts, new or worsening depression, or suicidal ideation to your doctor immediately. Prior to commencing treatment, disclose any kidney or liver conditions, and provide a complete list of current medications to your doctor, as interactions may affect efficacy or alter the drug's action. Inform your doctor of pregnancy, pregnancy planning, or breastfeeding.

Uses of Pretual NT 75mg/10mg Tablet

Managing neuropathic pain

Major Benefits of Pretual NT 75mg/10mg Tablet:

Follow your doctor's instructions precisely regarding the dosage and treatment length for this medication. Ingest the 75mg/10mg Pretual NT Tablet whole; do not break, crush, or chew it. While it can be taken with or without food, consistent timing is recommended.

Common Side effects of Pretual NT 75mg/10mg Tablet:

  • Dryness in mouth
  • Increased heart rate
  • Sleepiness
  • Dizziness
  • Tiredness
  • Weight gain
  • Blurred vision
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Uncoordinated body movements
  • Increased appetite
  • Increased libido
  • Paresthesia (tingling or pricking sensation)
  • Vertigo
  • Vomiting
  • Nausea
  • Erectile dysfunction
  • Joint pain
  • Constipation
  • Difficulty in urination

How to use Pretual NT 75mg/10mg Tablet:

Follow your doctor's instructions precisely regarding dosage and treatment length for this medication. Ingest the 75mg/10mg Pretual NT Tablet whole; avoid chewing, crushing, or breaking it. While it can be taken with or without food, consistent timing is recommended.

How Pretual NT 75mg/10mg Tablet works:

Pretual NT 75mg/10mg tablets combine pregabalin and nortriptyline to alleviate neuropathic pain. Pregabalin, an alpha-2-delta ligand, reduces pain by adjusting nerve cell calcium channel function. Nortriptyline, a tricyclic antidepressant, elevates serotonin and noradrenaline—neurotransmitters that inhibit pain signal transmission in the brain. This dual action provides effective neuropathic pain relief.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Concurrent use of Pretual NT 75mg/10mg tablets and alcohol may lead to increased sleepiness.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Pretual NT 75mg/10mg Tablet during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to a developing fetus. A physician will assess the advantages against possible risks prior to prescription. Patient consultation with their doctor is advised.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Lactation and the use of Pretual NT 75mg/10mg tablets are likely incompatible. Available human data indicates potential transfer of the medication into breast milk, posing a possible risk to the infant.

DrivingDrivingUNSAFE

Driving ability may be impaired by Pretual NT 75mg/10mg Tablets, due to potential side effects that can reduce alertness.

KidneyKidneyCAUTION

Patients with kidney impairment should use Pretual NT 75mg/10mg tablets cautiously; dosage modification may be necessary. Physician consultation is advised.

LiverLiverSAFE IF PRESCRIBED

The use of Pretual NT 75mg/10mg Tablet in patients with liver impairment is likely safe, with current evidence indicating that dosage modification may be unnecessary. However, physician consultation is recommended.

What if you forget to take Pretual NT 75mg/10mg Tablet :

Should you forget a dose of Pretual NT 75mg/10mg Tablet, administer it at your earliest convenience. If, however, your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Pretual NT 75mg/10mg Tablet

LabelValue
Developing Habits No.
Type of Therapy Neuroscience (Central Nervous System)

FAQs on Pretual NT 75mg/10mg Tablet

Pretual NT 75mg/10mg tablets combine pregabalin and nortriptyline to treat nerve pain (neuropathic pain). It works by calming overactive or damaged nerves in the brain, reducing pain signals.
Don't discontinue Pretual NT 75mg/10mg Tablet even if your pain subsides. Follow your doctor's instructions. Abrupt cessation may cause withdrawal symptoms including anxiety, insomnia, nausea, pain, and sweating. A gradual dose reduction is recommended before stopping treatment entirely.
Pretual NT 75mg/10mg Tablets may increase appetite, potentially leading to weight gain. Preventing weight gain is simpler than losing it. Maintain a balanced diet with controlled portion sizes, avoiding calorie-dense foods like soft drinks, fried foods, chips, pastries, and sweets. Between meals, opt for fruits, vegetables, and low-calorie snacks instead of junk food. Regular exercise further helps prevent weight gain. Combining healthy eating and regular exercise may help you avoid weight increase.
Pretual NT 75mg/10mg Tablets can cause drowsiness or sudden sleepiness, sometimes without warning. Until you understand the medication's effects on you, refrain from driving, operating machinery, working at heights, or engaging in hazardous activities. Report any such episodes to your doctor.
Pretual NT 75mg/10mg Tablets may impact sexual function in both men and women, potentially causing reduced libido, erectile dysfunction, or difficulty achieving orgasm. Decreased satisfaction and discomfort during intercourse may also occur. Discuss any such issues with your doctor, but do not discontinue the medication without their advice.
Rarely, Pretual NT 75mg/10mg Tablets may cause serious side effects. Seek immediate medical help if you experience: altered body temperature, breathing difficulties, rapid heartbeat, weakness, gait instability, impaired coordination or slowed reflexes, unusual mood or behavioral shifts (including restlessness, anxiety, or agitation), depression, hallucinations, disordered thinking, blurred or double vision, involuntary eye movements (nystagmus), visual disturbances, or signs of frequent infections (fever, chills, sore throat, mouth sores). While infrequent, these side effects require prompt medical attention.
You may notice some improvement with Pretual NT 75mg/10mg Tablet after two weeks, but complete benefit typically takes two to three months, and sometimes longer.
Missed a dose of Pretual NT 75mg/10mg? If it's almost time for your next dose, skip the missed one. Otherwise, take it immediately and resume your regular schedule. Never double up on doses; this can cause harmful side effects. If unsure, contact your doctor for guidance.
Seek immediate medical attention, contacting your doctor or going to the nearest hospital, even without noticeable symptoms. Urgent care may be necessary. Overdose symptoms can include drowsiness, weakness, gait instability, diplopia, slurred speech or diarrhea, confusion, blurred vision, dizziness, fluctuating body temperature, respiratory difficulty, and tachycardia.
Higher doses than recommended won't necessarily improve effectiveness; instead, they risk serious side effects and toxicity. Consult your doctor for reevaluation if your symptoms worsen despite taking the recommended dose.
Pretual NT 75mg/10mg Tablets can affect your alertness and coordination. Avoid driving or operating machinery. Alcohol should be avoided as it may intensify Pretual NT's effects. Grapefruit and grapefruit juice may also interact negatively with this medication. Increased sun sensitivity is possible; wear protective clothing and sunscreen while outdoors.
Regular check-ups with your doctor are recommended while taking Pretual NT 75mg/10mg Tablets. Consult your doctor immediately if your symptoms don't improve with the prescribed dosage or if you experience troublesome side effects impacting your daily life.
Don't open the tablet packaging until needed. Store tablets in a cool, dry place, away from children. Dispose of unused medication properly to prevent accidental ingestion by children, pets, or others.
Pretual NT 75mg/10mg tablets combine pregabalin and nortriptyline to treat neuropathic pain. It soothes damaged or overly active nerves, reducing pain signals to the brain.
Don't discontinue Pretual NT 75mg/10mg Tablet even if your pain subsides. Follow your doctor's instructions. Abrupt cessation may cause withdrawal symptoms including anxiety, insomnia, nausea, pain, and sweating. A gradual dose reduction is recommended before complete discontinuation.
Pretual NT 75mg/10mg Tablets may increase appetite, potentially leading to weight gain. Preventing weight gain is simpler than losing it. Maintain a healthy, balanced diet without larger portions. Avoid high-calorie foods like soft drinks, fried foods, chips, sweets, and baked goods. Between meals, choose fruits, vegetables, and low-calorie options instead of junk food. Regular exercise also helps prevent weight gain. Consistent healthy eating and regular exercise can minimize weight increase.
Pretual NT 75mg/10mg Tablets can cause drowsiness or sudden sleep onset, sometimes without warning. Therefore, avoid driving, operating machinery, working at heights, or engaging in hazardous activities, especially initially, until you understand the medication's effects on you. Report any such episodes to your doctor.
Pretual NT 75mg/10mg Tablets may impact sexual function in both men and women, potentially causing reduced libido, erectile dysfunction, difficulty achieving orgasm, decreased satisfaction, or discomfort during intercourse. Discuss any such issues with your doctor, but do not discontinue the medication without their advice.
While rare, Pretual NT 75mg/10mg Tablet can cause serious side effects. Seek immediate medical help if you experience: altered body temperature, breathing difficulties, rapid heartbeat, weakness, gait instability, impaired coordination or slowed reflexes, unusual mood or behavioral changes (including restlessness, anxiety, or agitation), depression, hallucinations, delusional thinking, vision problems (blurred, double vision, involuntary eye movements), impaired vision, or signs of frequent infection (fever, chills, sore throat, mouth sores). These side effects, though infrequent, require prompt medical attention.
You may notice initial improvements with Pretual NT 75mg/10mg Tablets within two weeks, though the full benefit usually takes two to three months to become apparent. Some individuals may require even longer.
Missed a dose of Pretual NT 75mg/10mg Tablet? If it's almost time for your next dose, skip the missed one and continue as usual. Otherwise, take it immediately and resume your regular schedule. Never double the dose; this can cause harmful side effects. If uncertain, contact your doctor for guidance.
Seek immediate medical attention, contacting your doctor or going to the nearest emergency room, even without noticeable symptoms. Urgent care may be necessary. Overdose symptoms can include drowsiness, weakness, unsteady gait, double vision, slurred speech, diarrhea, confusion, blurred vision, dizziness, fluctuating body temperature, breathing difficulties, and rapid heartbeat.
Increasing your dosage beyond what's recommended won't necessarily improve results; it could actually lead to severe side effects or toxicity. If your symptoms worsen despite taking the prescribed dose, seek medical advice.
Pretual NT 75mg/10mg Tablets may affect your alertness and coordination. Avoid driving or operating machinery while taking this medication. Alcohol consumption should be avoided as it can intensify Pretual NT's effects. Grapefruit and grapefruit juice may interact negatively; therefore, avoid them. Increased sun sensitivity is a potential side effect; wear protective clothing and sunscreen when outdoors.
Regular check-ups with your doctor are recommended while taking Pretual NT 75mg/10mg Tablets. Consult your doctor immediately if your symptoms don't improve with the prescribed dosage, or if you experience persistent side effects impacting your daily life.
Keep your tablets in their packaging until needed. Store in a cool, dry place, away from children. Dispose of unused medication properly to prevent accidental ingestion by children, pets, or others.
Pretual NT 75mg/10mg tablets combine Pregabalin and Nortriptyline to treat nerve pain (neuropathic pain). It works by calming overactive or damaged nerves in the brain, reducing pain signals.
Don't discontinue Pretual NT 75mg/10mg Tablet even if your pain subsides. Follow your doctor's instructions. Abrupt cessation may cause withdrawal symptoms including anxiety, insomnia, nausea, pain, and sweating. A gradual dose reduction is recommended before stopping the medication entirely.
Pretual NT 75mg/10mg Tablets may increase appetite, potentially leading to weight gain. Preventing weight gain is simpler than losing it. Maintain a healthy, balanced diet without increasing portion sizes. Avoid high-calorie foods like soft drinks, fried foods, chips, pastries, and sweets. Between meals, choose fruits, vegetables, and low-calorie options instead of junk food. Regular exercise also helps prevent weight gain. Combining healthy eating and regular exercise may prevent any weight increase.
Drowsiness and sudden sleep onset are possible side effects of Pretual NT 75mg/10mg Tablet. These episodes may occur without warning. Refrain from driving, operating machinery, working at heights, or engaging in hazardous activities, especially initially, until you understand the medication's effects on you. Report any such incidents to your doctor.
Pretual NT 75mg/10mg Tablets may impact sexual function in both men and women, potentially causing reduced libido, erectile dysfunction (difficulty achieving or maintaining an erection), anorgasmia (inability to reach orgasm), decreased satisfaction, or discomfort during intercourse. Discuss any such issues with your doctor, but do not discontinue use without their advice.
Rarely, Pretual NT 75mg/10mg Tablets may cause serious side effects. Seek immediate medical help if you experience: altered body temperature, breathing difficulties, rapid heartbeat, weakness, gait instability, impaired coordination or slowed reflexes, unusual mood or behavior changes (agitation, anxiety, euphoria), depression, hallucinations, delusional thinking, visual disturbances (blurred vision, double vision, nystagmus), impaired vision, or signs of infection (fever, chills, sore throat, mouth sores). While infrequent, these necessitate prompt medical attention.
You may notice some improvement with Pretual NT 75mg/10mg Tablet within two weeks, but the full effects usually appear after two to three months. For some individuals, it may take longer.
Missed a dose of Pretual NT 75mg/10mg Tablet? If it's almost time for your next dose, skip the missed one and continue as usual. Otherwise, take it immediately and resume your regular schedule. Never double up on doses to compensate; this can lead to harmful side effects. If unsure, seek your doctor's advice.
Seek immediate medical attention, contacting your doctor or going to the nearest hospital's emergency room, even without noticeable symptoms. Urgent care may be necessary. Overdose symptoms can include drowsiness, weakness, gait instability, diplopia, slurred speech or diarrhea, confusion, blurred vision, dizziness, fluctuating body temperature, respiratory distress, and tachycardia.
Higher doses don't necessarily mean better results; they can actually increase the risk of serious side effects. If your symptoms worsen despite taking the recommended dose, consult your doctor.
Pretual NT 75mg/10mg Tablets may affect your alertness and coordination. Avoid driving or operating machinery. Do not consume alcohol while taking this medication as it can intensify its effects. Grapefruit and grapefruit juice may interact negatively; avoid them. Increased sun sensitivity is possible; wear protective clothing and sunscreen when outdoors.
Regular check-ups with your doctor are recommended while taking Pretual NT 75mg/10mg Tablets. Consult your doctor immediately if your symptoms don't improve with the prescribed dosage or if you experience persistent side effects impacting your daily life.
Don't open the tablet package until you're ready to take your medication. Store the package in a cool, dry place, out of children's reach. Dispose of unused medication properly to prevent accidental ingestion by children, pets, or others.
Pretual NT 75mg/10mg Tabl...
125
MRP 152
17% off