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RIFAKEM-INH 450MG/300MG CAPSULE

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Prescription Required

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Alkem Laboratories Ltd

Salt Composition

Rifampicin (450mg) + Isoniazid (300mg)

Overview RIFAKEM-INH 450MG/300MG CAPSULE

Combiflam-TB 450mg/300mg capsules are prescribed for tuberculosis treatment. This combination medication inhibits the growth of tuberculosis-causing bacteria. Always follow your physician's instructions for dosage and timing. Take the medication on an empty stomach at the same time daily for optimal effectiveness. Exceeding the recommended dose can be harmful. If a dose is missed, take it as soon as possible. Complete the entire course of treatment, even if symptoms improve; premature cessation can reduce its effectiveness. Therapeutic effects may take time to manifest. Consult your doctor if symptoms worsen or fail to improve. Common side effects include nausea, vomiting, fever, dark urine, sweating, increased salivation, etc. Hydration is crucial to manage side effects. Report any worsening side effects immediately. While serious adverse events are uncommon, seek immediate medical attention for allergic reactions (rashes, itching, swelling, breathing difficulties). Inform your doctor of all other medications before starting this treatment. Patients with liver or kidney conditions require careful monitoring and should consult their doctor. Pregnant or breastfeeding individuals should also seek medical advice. Alcohol should be avoided due to potential increased drowsiness. While this medication usually doesn't affect driving ability, avoid driving if drowsiness or dizziness occurs. Maintain adequate rest and a balanced diet for faster recovery. Your doctor may order lab tests to monitor the medication's effects.

Uses of RIFAKEM-INH 450MG/300MG CAPSULE

Managing Tuberculosis (TB) Infection

Major Benefits of RIFAKEM-INH 450MG/300MG CAPSULE:

Follow your doctor's instructions precisely regarding dosage and treatment length for this medication. Consume RIFAKEM-INH 450MG/300MG CAPSULES on an empty stomach. Refrain from consuming tyramine-rich foods, including certain cheeses, smoked seafood, processed meats, and some beers, while taking RIFAKEM-INH 450MG/300MG CAPSULES.

Common Side effects of RIFAKEM-INH 450MG/300MG CAPSULE:

  • Dark colored urine
  • Rash
  • Vomiting
  • Jaundice
  • Fever
  • Increased liver enzymes
  • Nausea
  • Peripheral neuropathy (tingling and numbness of feet and hand)

How to use RIFAKEM-INH 450MG/300MG CAPSULE:

Follow your physician's instructions precisely regarding dosage and treatment length for this medication. RIFAKEM-INH 450MG/300MG CAPSULES should be administered on an empty stomach. Refrain from consuming tyramine-rich foods, including cheeses, cured meats, smoked fish, and certain beers, while taking RIFAKEM-INH 450MG/300MG CAPSULES.

How RIFAKEM-INH 450MG/300MG CAPSULE works:

Rifampicin and isoniazid, combined as RIFAKEM-INH 450MG/300MG capsules, effectively combat tuberculosis (TB). This antibiotic duo functions synergistically: Rifampicin disables a crucial bacterial enzyme (RNA polymerase), halting TB's protein synthesis and replication. Simultaneously, isoniazid interferes with the bacteria's protective cell wall formation. This combined action leads to bacterial destruction and disease eradication.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Concurrent use of RIFAKEM-INH 450MG/300MG CAPSULE and alcohol can lead to adverse reactions including facial flushing, tachycardia, nausea, polydipsia, chest discomfort, and hypotension (a Disulfiram-like effect).

PregnancyPregnancyCONSULT YOUR DOCTOR

Pregnancy use of RIFAKEM-INH 450MG/300MG capsules carries potential risks. While human data is scarce, animal research indicates potential harm to a fetus. Prescription will depend on a risk-benefit assessment by your physician. Seek medical advice before using this medication.

Breast feedingBreast feedingSAFE IF PRESCRIBED

Rifaximin/Isoniazid 450mg/300mg capsules are considered safe for breastfeeding mothers. Research in humans indicates minimal drug transfer to breast milk, posing no discernible risk to the infant.

DrivingDrivingUNSAFE

Taking RIFAKEM-INH 450MG/300MG capsules may induce adverse reactions impacting driving capabilities. These capsules can lead to seizures, psychiatric disorders, and optic neuritis (optic nerve inflammation potentially resulting in visual impairment), all of which could compromise safe driving.

KidneyKidneyCAUTION

Patients with kidney impairment should use Rifakem-INH 450mg/300mg capsules cautiously; dosage modification may be necessary. Physician consultation is advised.

LiverLiverCAUTION

Patients with liver impairment should use Rifakem-INH 450mg/300mg capsules cautiously, potentially requiring dosage modification. Consult a physician for guidance. Rifakem-INH 450mg/300mg capsules are contraindicated in individuals with severe hepatic dysfunction.

What if you forget to take RIFAKEM-INH 450MG/300MG CAPSULE :

Forgo Rifakem-INH 450mg/300mg capsules? Take it immediately if you remember. But, nearing your next scheduled dose? Omit the missed one and resume your usual regimen. Never take a double dose.

Facts to Know About RIFAKEM-INH 450MG/300MG CAPSULE

LabelValue
Addictive None.
Medication Classification Antimicrobial agents

FAQs on RIFAKEM-INH 450MG/300MG CAPSULE

Rifampicin and isoniazid, combined as RIFAKEM-INH 450MG/300MG capsules, treat tuberculosis. Rifampicin disables a crucial bacterial enzyme (RNA polymerase), halting tuberculosis bacteria's protein synthesis and replication. Isoniazid inhibits the formation of the bacteria's protective cell wall. This dual action results in bacterial death and infection resolution.
Complete the prescribed medication regimen. Do not discontinue prematurely, even if symptoms improve. Refrain from alcohol consumption during treatment, as it elevates the risk of liver damage. Report any visual disturbances, appetite loss, fatigue, abdominal pain, nausea, vomiting, jaundice, or dark urine to your physician immediately.
Follow your physician's instructions precisely when administering the 450mg/300mg RIFAKEM-INH capsule. Optimal absorption occurs when taken on an empty stomach, at least an hour before or two hours after eating.
Indeed, the medication RIFAKEM-INH 450MG/300MG CAPSULE may alter the coloration of bodily fluids, including urine, skin, sweat, saliva, tears, and feces, to a brownish-red or orange hue. This discoloration is benign.
Indeed, concurrent use of RIFAKEM-INH 450MG/300MG capsules may reduce the efficacy of oral contraceptives. Therefore, consult your physician regarding alternative birth control options that do not rely on hormonal regulation, including barrier methods like condoms, diaphragms, and spermicides.
Store this medication in its original, tightly sealed container or packaging, following the storage instructions provided on the label. Discard any leftover medication and ensure it remains inaccessible to children, pets, and other individuals.
RIFAKEM-INH 450MG/300MG C...
56
MRP 68
17% off