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Safemin-PGM Tablet SR

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Prescription Required

Marketer

Reward Pharmaceuticals

Salt Composition

Pregabalin (75mg) + Nortriptyline (10mg) + Methylcobalamin (1500mcg)

Overview Safemin-PGM Tablet SR

Neuropathic pain is effectively managed by the sustained-release Safemin-PGM Tablet SR, a combination drug. Its mechanism involves modulating nerve cell calcium channel activity to reduce pain signaling. Concurrently, it elevates brain neurotransmitters, improving mood and safeguarding nerve fibers. Safemin-PGM Tablet SR may be ingested with or without food; however, consistent daily timing ensures stable blood levels. Adhere strictly to your physician's prescribed dosage and duration. Missed doses should be taken immediately upon recollection. Complete the entire course, even with symptom improvement. Abrupt cessation is strongly discouraged, as it can exacerbate symptoms. Common side effects include constipation, weight increase, and xerostomia. Drowsiness and dizziness are possible; avoid activities requiring alertness until the drug's effects are understood. Weight gain may occur; a balanced diet and regular exercise are recommended. Report any unusual mood or behavioral shifts, new or worsening depression, or suicidal ideation to your doctor immediately. Prior to commencing treatment, disclose any kidney or liver conditions, and provide a complete list of current medications, as interactions may compromise efficacy or alter the drug's action. Inform your doctor if you are pregnant, considering pregnancy, or breastfeeding.

Primary Ingredients of Safemin-PGM Tablet SR

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Uses of Safemin-PGM Tablet SR

Managing neuropathic pain

Major Benefits of Safemin-PGM Tablet SR:

Administer this medication precisely as prescribed by your physician, adhering to both the dosage and treatment duration. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Safemin-PGM Tablet SR can be consumed with or without food; however, consistent daily timing is recommended.

Common Side effects of Safemin-PGM Tablet SR:

  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Increased heart rate
  • Difficulty in urination
  • Decreased appetite
  • Nausea
  • Vomiting
  • Constipation
  • Weight gain
  • Dizziness
  • Sleepiness
  • Tiredness
  • Blurred vision
  • Dryness in mouth
  • Uncoordinated body movements
  • Diarrhea
  • Headache

How to use Safemin-PGM Tablet SR:

Administer this medication precisely as your physician directs, adhering to both the prescribed dosage and treatment duration. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Safemin-PGM Tablet SR can be consumed with or without food, though consistent timing is recommended.

How Safemin-PGM Tablet SR works:

Safemin-PGM SR tablets contain Pregabalin, Nortriptyline, and Methylcobalamin, working synergistically to alleviate neuropathic pain. Pregabalin, an alpha-2-delta ligand, reduces pain transmission by modulating nerve cell calcium channels. Nortriptyline, a tricyclic antidepressant, elevates serotonin and noradrenaline levels, thereby inhibiting pain signal transmission to the brain. Methylcobalamin, a B vitamin, promotes myelin production, protecting nerve fibers and aiding in the repair of damaged nerve cells. This combined action provides effective relief from nerve-related pain.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Concurrent use of Safemin-PGM extended-release tablets and alcohol may result in significant sedation.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Safemin-PGM Tablet SR during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to the fetus. A physician will assess the advantages against possible risks prior to prescribing. Seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Prolonged-release Safemin-PGM tablets are likely unsafe for breastfeeding mothers. Available human data indicates potential transfer to breast milk, posing a risk to the infant.

DrivingDrivingUNSAFE

Driving ability may be impaired by Safemin-PGM Tablet SR, due to potential side effects that can reduce alertness.

KidneyKidneyCAUTION

Patients with kidney impairment should use Safemin-PGM Tablet SR cautiously, as dose modification may be necessary. Physician consultation is advised.

LiverLiverSAFE IF PRESCRIBED

Safemin-PGM Tablet SR appears to pose minimal risk for individuals with hepatic impairment. Available evidence indicates dose modification may be unnecessary; however, physician consultation is recommended.

What if you forget to take Safemin-PGM Tablet SR :

Should you forget a Safemin-PGM Tablet SR dose, take it immediately. Nevertheless, if your next dose is imminent, omit the missed one and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Safemin-PGM Tablet SR

LabelValue
Developing Habits No.
Treatment Category Neuroscience of the Central Nervous System

FAQs on Safemin-PGM Tablet SR

Safemin-PGM SR tablets combine gabapentin, nortriptyline, and methylcobalamin to treat neuropathic pain. The medication soothes damaged or overly active nerves by affecting the brain, reducing pain signals. It also promotes nerve regeneration.
Don't discontinue Safemin-PGM Tablet SR prematurely, even if your pain subsides. Follow your doctor's instructions. Abrupt cessation may cause withdrawal symptoms including anxiety, insomnia, nausea, pain, and sweating. A gradual dose reduction is recommended before complete discontinuation.
Safemin-PGM SR Tablets may increase appetite, potentially leading to weight gain. Preventing this weight gain is simpler than losing it later. Maintain a healthy, balanced diet without increasing portion sizes. Avoid high-calorie foods like soft drinks, fried foods, chips, cakes, biscuits, and sweets. Between meals, opt for fruits, vegetables, and low-calorie snacks instead of junk food. Regular exercise further helps prevent weight gain. A combination of healthy eating and regular exercise can minimize or prevent weight increase.
Safemin-PGM Tablet SR can cause drowsiness and sudden sleepiness, sometimes without warning. Therefore, avoid potentially hazardous activities like driving, operating machinery, or working at heights, especially when you first start taking this medication. Report any such episodes to your doctor.
Safemin-PGM Tablet SR may impact sexual function in both men and women, potentially causing reduced libido, erectile dysfunction (difficulty achieving or maintaining an erection), anorgasmia (inability to reach orgasm), decreased sexual satisfaction, or discomfort during intercourse. Consult your doctor if you experience these side effects, but do not discontinue Safemin-PGM Tablet SR without medical advice.
Safemin-PGM Tablet SR rarely causes serious side effects. However, seek immediate medical help if you experience: altered body temperature, breathing difficulties, rapid heartbeat, weakness, gait instability, impaired coordination or slowed reflexes, unusual mood or behavioral changes (including restlessness, anxiety, or agitation), depression, hallucinations, disordered thinking, vision problems (blurred vision, double vision, nystagmus), or frequent infections (fever, chills, sore throat, mouth sores). While uncommon, these side effects require prompt medical attention.
You may notice some improvement with Safemin-PGM Tablet SR after two weeks, but complete benefits may take two to three months or longer.
Missed a Safemin-PGM Tablet SR dose? If it's nearly time for your next dose, skip the missed one and continue as usual. Otherwise, take it immediately and resume your regular schedule. Never double the dose; this could cause side effects. If unsure, ask your doctor for guidance.
Seek immediate medical attention, contacting your doctor or going to the nearest hospital, even without noticeable symptoms. Urgent care may be necessary. Overdose symptoms can include drowsiness, weakness, gait instability, diplopia, slurred speech or diarrhea, confusion, blurred vision, dizziness, fluctuating body temperature, respiratory distress, and tachycardia.
Exceeding the recommended dosage won't necessarily improve effectiveness; it could significantly increase the risk of serious side effects and toxicity. If your symptoms worsen despite taking the recommended dose, consult your doctor for reassessment.
Safemin-PGM Tablet SR can affect your alertness and coordination. Avoid driving or operating machinery while taking it. Alcohol consumption should be avoided as it can intensify Safemin-PGM Tablet SR's effects. Grapefruit and grapefruit juice may also interact negatively with this medication. Increased sun sensitivity is possible; protect yourself from the sun with clothing and sunscreen during daytime exposure.
Regular checkups with your doctor are recommended while taking Safemin-PGM Tablet SR. Consult your doctor immediately if your symptoms don't improve with the prescribed dosage, or if side effects interfere with your daily life.
Don't open the tablet packaging until needed. Store unopened tablets in a cool, dry place, away from children. Dispose of unused medication properly to prevent accidental ingestion by children, pets, or others.
Safemin-PGM Tablet SR does expire. Check the package for the expiration date and discard the medication after that date.
Safemin-PGM Tablet SR
172
MRP 199
13% off