Sheath-N Tablet SR
Marketer
Entrust Healthcare Pvt Ltd
Salt Composition
Pregabalin (75mg) + Nortriptyline (10mg)
Overview Sheath-N Tablet SR
Neuropathic pain is effectively managed by the extended-release formulation, Sheath-N Tablet SR, a dual-action analgesic. This medication reduces pain transmission to the brain. Administered orally, Sheath-N Tablet SR can be taken with or without food, ideally before sleep, consistently at the same time daily for optimal blood levels. Follow your physician's prescribed dosage and duration precisely, as it possesses habit-forming properties. Missed doses should be taken immediately upon recall. Complete the entire course of treatment regardless of symptom improvement. Abrupt cessation requires prior consultation with your doctor. Common side effects include constipation, urinary difficulty, weight gain, fatigue, and dry mouth. Dizziness and drowsiness may occur, necessitating caution with activities demanding concentration. Weight gain may be experienced; counter this through regular exercise and a balanced diet. Report any unusual mood swings, behavioral changes, new or worsening depression, or suicidal ideation to your doctor. Prior to commencing treatment, disclose any kidney or liver conditions, and provide a complete list of all current medications, as interactions can affect efficacy. Inform your doctor of pregnancy, pregnancy plans, or breastfeeding.
Uses of Sheath-N Tablet SR
Managing neuropathic pain
Major Benefits of Sheath-N Tablet SR:
Administer this medication precisely as your physician directs, adhering to both the prescribed dosage and treatment period. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Sheath-N SR tablets can be consumed with or without food, although consistent timing is recommended.
Common Side effects of Sheath-N Tablet SR:
- Dryness in mouth
- Increased heart rate
- Sleepiness
- Dizziness
- Tiredness
- Weight gain
- Blurred vision
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Uncoordinated body movements
- Increased appetite
- Increased libido
- Paresthesia (tingling or pricking sensation)
- Vertigo
- Vomiting
- Nausea
- Erectile dysfunction
- Joint pain
- Constipation
- Difficulty in urination
How to use Sheath-N Tablet SR:
Administer this medication according to your physician's prescribed dosage and schedule. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Sheath-N SR tablets can be consumed with or without food, although consistent timing is recommended.
How Sheath-N Tablet SR works:
Sheath-N SR tablets contain pregabalin and nortriptyline, working synergistically to manage neuropathic pain. Pregabalin, an alpha-2-delta calcium channel ligand, reduces pain transmission by modulating nerve cell calcium influx. Nortriptyline, a tricyclic antidepressant, elevates serotonin and norepinephrine levels, thereby inhibiting pain signal propagation within the central nervous system. This dual mechanism effectively alleviates pain originating from nerve damage.
SAFETY ADVICE
AlcoholUNSAFE
Concomitant use of Sheath-N Tablet SR and alcohol may result in increased sleepiness.
PregnancyCONSULT YOUR DOCTOR
The extended-release Sheath-N Tablet may pose risks during pregnancy. While human data is scarce, animal research indicates potential harm to a developing fetus. A physician will assess the advantages against possible dangers prior to prescription. Physician consultation is advised.
Breast feedingCONSULT YOUR DOCTOR
Extended-release Sheath-N tablets are likely not safe for breastfeeding mothers. Preliminary human research indicates potential transfer to breast milk, posing a possible risk to the infant.
DrivingUNSAFE
Driving ability may be impaired by Sheath-N Tablet SR, due to potential side effects impacting alertness.
KidneyCAUTION
Patients with impaired kidney function should exercise caution when using Sheath-N Tablet SR. Dosage modification of Sheath-N Tablet SR might be necessary. Physician consultation is recommended.
LiverSAFE IF PRESCRIBED
Use of Sheath-N Tablet SR in patients with liver impairment appears to pose minimal risk. Current evidence indicates dose modification may be unnecessary, but physician consultation is recommended.
What if you forget to take Sheath-N Tablet SR :
Should you forget a Sheath-N Tablet SR dose, take it immediately. Nevertheless, if your next dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.
Facts to Know About Sheath-N Tablet SR
| Label | Value |
|---|---|
| Developing Habits | No. |
| Type of Therapy | Neuroscience (Central Nervous System) |


