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Shilstine 50mg Injection

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Prescription Required

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Shilpa Medicare Ltd

Salt Composition

Calcium Leucovorin (50mg)

Overview Shilstine 50mg Injection

Leucovorin 50mg Injection counteracts the adverse consequences of methotrexate, a cancer treatment drug. It also serves as an antidote for methotrexate overdose. Administered intravenously at a slow rate under medical supervision, dosage and frequency are determined by your physician based on your specific condition and may vary. Strict adherence to your doctor's instructions is vital, as incorrect usage or overdosage can lead to severe adverse reactions. Injection site inflammation (pain, swelling, redness) is a frequent side effect; report any concerning symptoms to your doctor for potential mitigation strategies. Regular blood tests are necessary to monitor blood cell counts and methotrexate serum levels. Prior to treatment, disclose any history of seizures, liver or kidney dysfunction, or current use of anti-infective medications. Inform your healthcare provider of all medications, particularly phenytoin (if used for seizures), as drug interactions are possible. Pregnant or breastfeeding individuals should consult their physician before commencing treatment to ensure safety.

Primary Ingredients of Shilstine 50mg Injection

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Uses of Shilstine 50mg Injection

Mitigating Methotrexate-Related Adverse Events

Major Benefits of Shilstine 50mg Injection:

This medication will be administered by your physician or registered nurse; self-medication is strictly prohibited.

Common Side effects of Shilstine 50mg Injection:

  • Injection site reactions (pain, swelling, redness)

How to use Shilstine 50mg Injection:

This medication will be administered by your healthcare provider; please do not attempt self-medication.

How Shilstine 50mg Injection works:

Vitamine B-based Shilstine 50mg Injection safeguards healthy cells from methotrexate's (antineoplastic agent) toxicity, enabling selective cancer cell destruction.

SAFETY ADVICE

AlcoholAlcoholCONSULT YOUR DOCTOR

The safety of combining Shilstine 50mg Injection with alcohol is undetermined. Seek medical advice before doing so.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Shilstine 50mg Injection during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to the fetus. A physician will assess the potential advantages against any possible dangers prior to prescribing. Seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Data on the compatibility of Shilstine 50mg Injection with breastfeeding is currently unavailable. Seek professional medical advice.

DrivingDrivingSAFE

Administering Shilstine 50mg Injection typically does not impair driving ability.

KidneyKidneyCONSULT YOUR DOCTOR

Data regarding Shilstine 50mg Injection's use in individuals with renal impairment is scarce. Physician consultation is advised.

LiverLiverCONSULT YOUR DOCTOR

Data regarding Shilstine 50mg Injection's use in individuals with hepatic impairment is scarce. Physician consultation is advised.

What if you forget to take Shilstine 50mg Injection :

Should you forget a Shilstine 50mg Injection, administer it immediately. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Shilstine 50mg Injection

LabelValue
Chemical Type Glutamate Derivatives
Developing Habits No.
Treatment Category KINSHIP
Behavioral Class Methotrexate as a cytoprotective agent

FAQs on Shilstine 50mg Injection

Shilstine 50mg Injection counteracts methotrexate's adverse effects during cancer treatment, manages methotrexate overdose, and treats megaloblastic anemia stemming from folic acid deficiency when oral medication is impractical.
Anemia is a condition where the blood carries less oxygen than normal due to a reduced number of red blood cells. Megaloblastic anemia, a type of anemia, features abnormally large red blood cells and a lower-than-normal cell count, typically stemming from vitamin B12 or folic acid deficiency. How quickly does a 50mg Shilstine injection take effect?
Shilstine 50mg Injection typically begins working within five minutes, although the onset may differ based on individual factors and the administered dose.
To determine the correct Shilstine 50mg Injection dosage and treatment length, your doctor will order blood tests. These include serum methotrexate levels (if you're taking methotrexate or have overdosed), a complete blood count to check for megaloblastic anemia, and calcium levels to prevent hypercalcemia, as Shilstine 50mg Injection contains calcium.
Ensure adequate hydration (urine output >2500 mL/day) by increasing oral or IV fluids 12 hours pre- and 36 hours post-methotrexate infusion. Monitor urine alkalinization (pH >7.0) prior to infusion to optimize excretion. Avoid acidic foods, drinks, and medications during treatment. Measure serum methotrexate levels at 24, 48, and 72 hours post-infusion.
Shilstine 50mg Injection
229
MRP 265
13% off