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Siaglide-M 50/500 Tablet PR

Prescription Icon
Prescription Required

Marketer

Abbott

Salt Composition

Sitagliptin (50mg) + Metformin (500mg)

Overview Siaglide-M 50/500 Tablet PR

Diabex Duo 50/500 tablets are a dual-action medication managing elevated blood glucose in type 2 diabetes. This helps mitigate serious diabetic complications like renal impairment and vision loss, potentially lowering stroke and heart attack risk. Diabex Duo 50/500 may be used independently or in conjunction with other antidiabetic therapies. Optimal results require adherence to a balanced diet and regular physical activity. Dosage is personalized, based on your health status, glucose levels, and other medications. Consuming it with food minimizes gastrointestinal distress. Consistent daily intake, at the same time, maximizes effectiveness; discontinue only under physician guidance. Maintaining your prescribed diet and exercise plan is crucial for diabetes control; lifestyle significantly impacts management. Common side effects include nausea, vomiting, diarrhea, stomach upset, headache, and pharyngitis. Hypoglycemia is a potential adverse effect, especially when combined with insulin or sulfonylureas; learn its signs and treatment. This medication isn't universally suitable. Inform your physician of any pre-existing kidney, liver, heart, or pancreatic conditions, or significant alcohol consumption before initiating treatment. Pregnant or lactating individuals require medical consultation prior to use. Interactions with other medications are possible; disclose all medications to your doctor to ensure safety. Alcohol should be limited due to its hypoglycemic effect. Your doctor will monitor kidney function and blood sugar levels throughout your treatment.

Uses of Siaglide-M 50/500 Tablet PR

Managing type 2 diabetes

Major Benefits of Siaglide-M 50/500 Tablet PR:

Follow your physician's instructions or consult the product label for dosage guidance. Administer Siaglide-M 50/500 Tablet PR with a meal.

Common Side effects of Siaglide-M 50/500 Tablet PR:

  • Decreased appetite
  • Vomiting
  • Upper respiratory tract infection
  • Hypoglycemia (low blood glucose level)
  • Abdominal bloating
  • Nausea
  • Diarrhea

How to use Siaglide-M 50/500 Tablet PR:

Follow your doctor's instructions or consult the product information leaflet for guidance. Administer Siaglide-M 50/500 Tablet PR with a meal.

How Siaglide-M 50/500 Tablet PR works:

Siaglide-M 50/500 PR tablets combine sitagliptin and metformin to manage blood glucose. Sitagliptin enhances insulin production by the pancreas, improves insulin utilization, and decreases hepatic glucose output. Metformin, a biguanide, reduces liver glucose production, slows intestinal glucose absorption, and increases insulin sensitivity. This dual action results in superior glycemic control.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Consuming alcohol concurrently with Siaglide-M 50/500 Tablet PR is inadvisable.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Siaglide-M 50/500 Tablet PR during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to the fetus. A physician will assess the potential advantages against any possible risks prior to prescribing. Seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

The use of Siaglide-M 50/500 Tablet PR while breastfeeding is likely inadvisable. Available human data indicates potential transfer of the medication into breast milk, posing a possible risk to the infant.

DrivingDrivingCAUTION

Driving ability can be impaired by both hypoglycemia and hyperglycemia. Refrain from driving if you experience these conditions.

KidneyKidneyCAUTION

Patients with kidney impairment should use Siaglide-M 50/500 Tablet PR cautiously, potentially requiring dosage modification. Severe kidney disease contraindicates its use. Physician consultation is recommended. Kidney function should be regularly monitored during treatment with this medication.

LiverLiverUNSAFE

The use of Siaglide-M 50/500 Tablet PR is likely inadvisable for individuals with hepatic impairment and should be omitted. Seek medical counsel.

What if you forget to take Siaglide-M 50/500 Tablet PR :

Should you forget a Siaglide-M 50/500 Tablet PR dose, administer it promptly. Nevertheless, if your next scheduled dose is imminent, omit the missed one and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Siaglide-M 50/500 Tablet PR

LabelValue
Developing Habits No.
Treatment Category Diabetes Management

FAQs on Siaglide-M 50/500 Tablet PR

Siaglide-M 50/500 Tablet PR combines sitagliptin and metformin to manage type 2 diabetes in adults. This combination improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin boosts insulin release by inhibiting DPP-4. This medication is not suitable for individuals under 18.
Prolonged use of Siaglide-M 50/500 Tablet PR can lead to vitamin B12 deficiency by hindering its absorption in the stomach. This deficiency may cause anemia, nerve damage (manifested as tingling, numbness in extremities, weakness, and urinary issues), and cognitive changes (including balance problems). To mitigate these risks, annual supplemental vitamin B12 is recommended by some researchers.
Siaglide-M 50/500 Tablet PR may cause common side effects such as hypoglycemia, taste changes, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use can also result in vitamin B12 deficiency.
Siaglide-M 50/500 Tablet PR is contraindicated in patients with allergies to its components or excipients, and those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Siaglide-M 50/500 Tablet PR with alcohol is unsafe and may heighten the risk of lactic acidosis.
Store this medication in its original, tightly closed container, following the storage instructions on the label or packaging. Discard any unused medication and keep it out of reach of children, pets, and others.
Sitagliptin/metformin (Siaglide-M 50/500 Tablet PR) can cause lactic acidosis (MALA, or metformin-associated lactic acidosis), a serious medical emergency resulting from excessive blood lactic acid. This rare side effect necessitates avoiding this medication in patients with kidney disease, the elderly, or those who consume significant alcohol. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If you experience these, discontinue Sitagliptin/metformin immediately and seek medical attention.
Siaglide-M 50/500 Tablet PR combines sitagliptin and metformin to treat type 2 diabetes mellitus in adults. This medication improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin increases insulin release by inhibiting DPP-4. It's not suitable for individuals under 18.
Siaglide-M 50/500 Tablet PR may cause common side effects such as hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory tract infections. Rare but serious side effects include lactic acidosis. Prolonged use may also result in vitamin B12 deficiency.
Siaglide-M 50/500 Tablet PR is contraindicated in patients with known allergies to its components or excipients, and in those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Siaglide-M 50/500 Tablet PR with alcohol is unsafe and may heighten the risk of lactic acidosis.
Sitagliptin/Metformin (Siaglide-M 50/500 Tablet PR) can cause lactic acidosis (MALA, Metformin-associated lactic acidosis), a serious medical emergency resulting from excessive blood lactic acid. This rare side effect necessitates caution in patients with kidney disease, the elderly, or those consuming significant alcohol. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If these occur, discontinue Sitagliptin/Metformin and seek immediate medical attention.
Prolonged Siaglide-M 50/500 Tablet PR use can lead to vitamin B12 deficiency by impairing its absorption. This deficiency, if left untreated, may result in anemia, neurological issues such as tingling, numbness in extremities, weakness, urinary problems, cognitive changes, and ataxia. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication and ensure it's inaccessible to children, pets, and others.
Siaglide-M 50/500 Tablet PR combines sitagliptin and metformin to treat type 2 diabetes in adults. This combination improves blood glucose control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin increases insulin release by inhibiting DPP-4. This medication is not suitable for individuals under 18.
Siaglide-M 50/500 Tablet PR may cause common side effects such as hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use may result in vitamin B12 deficiency.
Siaglide-M 50/500 Tablet PR is contraindicated in patients with allergies to its components or excipients, and in those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Siaglide-M 50/500 Tablet PR with alcohol is unsafe and may heighten the risk of lactic acidosis.
Sitagliptin/metformin (Siaglide-M 50/500 Tablet PR) can cause lactic acidosis (MALA, Metformin-associated lactic acidosis), a serious medical emergency resulting from excessive blood lactic acid. This rare side effect necessitates avoidance in patients with kidney disease, the elderly, or those consuming significant alcohol. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If experienced, discontinue Sitagliptin/metformin and seek immediate medical attention.
Prolonged use of Siaglide-M 50/500 Tablet PR can lead to vitamin B12 deficiency by hindering its absorption. This deficiency may cause anemia and neurological issues, including numbness and tingling in the extremities, weakness, urinary problems, cognitive changes, and balance difficulties (ataxia). To mitigate these risks, supplemental vitamin B12 is recommended at least annually, according to some research.
Store this medication in its original, tightly closed container, as directed on the label. Discard any unused medication; keep it out of reach of children, pets, and others.
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